
Location of Illinois in the U.S. map
This is a list of notable individuals who come from the state of Illinois, a state within the larger United States of America.
A
Aa–Ag
- Emma Abbott (1850–91), opera soprano. Born and raised in Illinois until age 16; funeral held in Illinois, but interred in Massachusetts.[1]
 - David Abidor (born 1992), soccer player
 - Margaret Abbott (1878–1955), first modern-era Olympic United States female champion. Lived during her teens and learned her Olympic sport of golf in Illinois.[2]
 - Robert Sengstacke Abbott (1868–1940), African-American lawyer, newspaper publisher and editor. Studied law and had his newspaper career in Chicago.[3]
 - Jessica Abel (1969–living), comic book writer and artist. Born and educated in Illinois.[4]
 - Gertrude Abercrombie (1909–77), surrealist painter. Lived most of her life in Chicago and known for her association with the city.[5]
 - Max Abramovitz (1908–2004), architect. Born and college-educated in Illinois.[6]
 - Ben Abruzzo (1930–85), balloonist. Born and college-educated in Illinois.[7]
 - Tony Accardo (1906–1992), organized crime figure. Born and lived entire life in Chicago metropolitan area.[8]
 - Barbara Acklin (1943–98), singer. Came to Illinois aged five and resided until her death.[9]
 - Ron Acks (1944–living), NFL linebacker 1968–76. Acks was born, attended high school and college in Illinois.[10]
 - Valdas Adamkus (1926–living), president of Lithuania 1998–2009. Lived in Illinois for a number of years after emigrating to the United States from Lithuania, getting a college degree and entering Chicago politics.[11]
 - Mike Adamle, NFL and Northwestern running back, TV personality
 - Berle Adams (1917–2009), founder of Mercury Records. Born and lived first thirty years in Illinois.[12]
 - Franklin P. Adams (1881–1960), writer, member of Algonquin Round Table. Described as "a native of Chicago", he found fame and lived most of his life in New York.[13]
 - John Hicks Adams (1820–78), gunslinger, Wild West lawman. Born and attended college in Illinois.[14]
 - Katrina Adams (1968–living), president of United States Tennis Association. Born and educated in Illinois.[15]
 - Robert McCormick Adams Jr., anthropologist, secretary of Smithsonian Institution
 - Jane Addams, social worker, teacher, Nobel Peace Prize recipient
 - George Ade, author and cartoonist (born in Indiana)
 - Paul Adelstein, actor, Prison Break, Private Practice
 - Victor Adeyanju, NFL defensive end 2006–10
 - Dankmar Adler, architect (born in Germany)
 - David Adler, architect (born in Wisconsin)
 - Lou Adler, music producer in Rock and Roll Hall of Fame
 - Max Adler, founder of Adler Planetarium
 - Scott Adsit, actor, writer, improvisational comedian, 30 Rock, Big Hero 6
 - John Agar, actor, Sands of Iwo Jima, She Wore a Yellow Ribbon, husband of Shirley Temple
 - Alex Agase, football player for Cleveland Browns; head coach of Northwestern, Purdue
 - Lou Agase, football player for Illinois, coach of CFL's Toronto Argonauts
 - Milton Ager, composer, "Ain't She Sweet", "Happy Days Are Here Again"
 - Benjamin Agosto, ice dancer, 2006 Turin Olympics silver medalist
 - Mark Aguirre, forward for DePaul, NBA's Dallas Mavericks and Detroit Pistons; top pick of 1981 NBA draft
 
Ah–Am
- Gene Ahern, cartoonist
 - Joe Aiello, organized crime figure (born in Sicily)
 - Joseph Aiuppa, organized crime figure
 - Stan Albeck, basketball head coach, Bradley, Cleveland Cavaliers, San Antonio Spurs, Chicago Bulls
 - Abraham Adrian Albert, mathematician
 - Eddie Albert, Oscar-nominated actor, Green Acres, Switch, Oklahoma!, Roman Holiday, The Heartbreak Kid, The Longest Yard
 - Frankie Albert, quarterback and head coach for San Francisco 49ers, College Football Hall of Famer
 - Bruce Alberts, biochemist, original author of Molecular Biology of the Cell
 - Steve Albini, musician, producer
 - Ted Albrecht, offensive tackle for Purdue and Chicago Bears
 - James L. Alcorn, governor and U.S. Senator of Mississippi
 - Jody Alderson, swimmer, 1952 Olympic bronze medalist
 - Dorothy Aldis, children's author
 - J. Frank Aldrich, 19th Century U.S. Representative (born in Wisconsin)
 - Gus Alex, organized crime figure
 - Dan Alexander, football player, 2000 Alamo Bowl MVP
 - Houston Alexander, mixed martial artist
 - Linsey Alexander, blues musician (born in Mississippi)
 - Lorez Alexandria, jazz and gospel singer
 - Nelson Algren, author, The Man with the Golden Arm, A Walk on the Wild Side (born in Michigan)
 - Saul Alinsky, founder of modern community organizing and writer
 - Paul Alivisatos, president, University of Chicago
 - Brian Allard, MLB pitcher 1979–81
 - Jeff Allen, NFL offensive guard 2012-19
 - Joan Allen, Oscar-nominated actress, The Bourne Ultimatum, The Contender, The Upside of Anger, Nixon, Face/Off
 - Karen Allen, actress, Indiana Jones and the Kingdom of the Crystal Skull, Raiders of the Lost Ark, Animal House, Scrooged
 - Leo E. Allen, 14-term U.S. Representative
 - Leslie Allen, auto racer, ninth in 1930 Indianapolis 500
 - Rex Allen Jr., country singer, narrator of film Me, Myself and Irene
 - Ronnie Allen, professional pool player
 - Sandy Allen, tallest U.S. woman
 - Steve Allen, TV personality, actor, author, songwriter, first host of The Tonight Show (born in New York)
 - Tony Allen, NBA forward 2004-18, member of 2008 champion Boston Celtics
 - William J. Allen, judge, U.S. Representative (born in Tennessee)
 - Justin Allgaier, auto racer, 2008 ARCA RE/MAX Series champion
 - Fran Allison, radio-TV personality, Kukla, Fran and Ollie (born in Iowa)
 - Luther Allison, blues musician (born in Arkansas)
 - Samuel Allison, prominent physicist who worked on Manhattan Project
 - Arthur Allyn Jr., co-owner of Chicago White Sox in 1960s
 - John Allyn, owner of White Sox 1961–75
 - Alfred S. Alschuler, architect
 - Mike Alstott, fullback for Tampa Bay Buccaneers 1996–2007, Super Bowl XXXVII champion
 - Jonathan Alter, journalist and author
 - Michael J. Alter, real estate developer, owner of WNBA's Chicago Sky
 - John Peter Altgeld, Governor of Illinois 1893–97 (born in Germany)
 - Dave Altizer, MLB infielder 1906–11
 - Scott Altman, astronaut, four Space Shuttle missions
 - John Altschuler, screenwriter, Blades of Glory, Silicon Valley
 - Anita Alvarez, Cook County State's Attorney 2008-16
 - John Alvin, actor, The Beast with Five Fingers, Objective, Burma!
 - A.A. Ames, four-term mayor of Minneapolis
 - Edward Ames, founder, McKendree University (born in Ohio)
 - Knowlton Ames, college football player and coach
 - Rosemary Ames, actress, Our Little Girl, Pursued
 - Stephen E. Ambrose, author, historian, Band of Brothers
 - The American Breed, band, "Bend Me, Shape Me"
 - Warren Amling, Ohio State athlete in College Football Hall of Fame
 - Albert Ammons, jazz musician
 - Gene Ammons, jazz musician
 - Morey Amsterdam, actor and comedian, The Dick Van Dyke Show
 
An–Ar
- Merry Anders, actress, The Dalton Girls, Hear Me Good, Tickle Me
 - Arthur E. Andersen, founder of accounting firm
 - Alexandria Anderson, NCAA champion sprinter
 - Andree Anderson, ice dancer, member of Figure Skating Hall of Fame
 - Craig Anderson, NHL goaltender 2002-23
 - Gillian Anderson, Emmy Award-winning actress, The X-Files, The House of Mirth, Bleak House, Hannibal
 - J. J. Anderson, forward for Bradley and Utah Jazz
 - John B. Anderson, politician, U.S. Representative 1961–81, U.S. presidential candidate
 - Ken Anderson, NFL quarterback 1971–86, four-time Pro Bowl selection
 - Kevin Anderson, actor, Sleeping with the Enemy, Miles from Home, Hoffa
 - Kurt Anderson, football player and coach
 - Laurie Anderson, performance artist and musician
 - Les Anderson, auto racer, 11th in 1947 Indy 500
 - Margaret C. Anderson, editor and publisher (born in Indiana)
 - Nick Anderson, NBA and Illinois guard, first Orlando Magic draft pick
 - Philip Warren Anderson, Nobel Prize-winning physicist
 - Ray Anderson, musician
 - Robert Orville Anderson, founder of ARCO oil company
 - Sherwood Anderson, novelist (born in Ohio)
 - Walter Stratton Anderson, naval vice admiral, battleship commander
 - Fern Andra, circus performer, actress, director
 - Emil Andres, auto racer, drove in nine Indianapolis 500s
 - Bruce Andrews, poet
 - Stanley Andrews, actor, Death Valley Days
 - Ethel Percy Andrus, founder of AARP
 - Elmer Angsman, running back for Notre Dame, Chicago Cardinals
 - John Ankerberg, Christian evangelist, TV presenter
 - Morris Ankrum, actor
 - Ann-Margret, Oscar-nominated actress, Bye Bye Birdie, Viva Las Vegas, Carnal Knowledge, The Cincinnati Kid, Tommy (born in Sweden)
 - Beulah Annan, inspiration for "Roxie Hart" in play and film Chicago
 - Moses Annenberg, newspaper publisher (born in Prussia)
 - Frank Annunzio, politician (Democrat), 13-term U.S. Representative
 - Cap Anson, Hall of Fame infielder for Chicago White Stockings (born in Iowa)
 - Bessie Anthony, golfer, U.S. Women's Amateur champion
 - Luis Aparicio, Hall of Fame infielder for Chicago White Sox (born in Venezuela)
 - Clarence Applegran, basketball coach, Kentucky 1924–25
 - Amy Applegren, pro baseball player
 - Arthur I. Appleton, businessman, thoroughbred owner
 - Luke Appling, Hall of Fame infielder for White Sox (born in North Carolina)
 - Lee Archambault, astronaut
 - Robert Ardrey, playwright and screenwriter, Khartoum, The Three Musketeers
 - Leslie C. Arends, politician (Republican), U.S. Representative 1943–74, Majority and Minority Whip
 - Mark Arie, two gold medals in shooting at 1920 Olympics
 - Hub Arkush, publisher of Pro Football Weekly
 - Andrew Watson Armour III, meat-packing executive, philanthropist
 - Philip Danforth Armour, businessman, founder of Armour and Company (born in New York)
 - Terron Armstead, NFL offensive lineman
 - Matthew John Armstrong, actor, Heroes
 - Otis Armstrong, running back for Denver Broncos 1973–80
 - Billy Arnold, auto racer, won 1930 Indianapolis 500
 - Billy Boy Arnold, blues musician
 - Isaac N. Arnold, U.S. Representative, author (born in New York)
 - Cliff Arquette, comedian and actor (born in Ohio)
 - Lewis Arquette, actor, Sherlock Hound, Camp Candy, The Waltons
 - Patricia Arquette, Oscar and Emmy-winning actress, Boyhood, Medium, True Romance, CSI: Cyber
 - Gerry Arrigo, MLB pitcher 1961–70
 
As–Az
- Jon Asamoah, NFL offensive lineman 2010-15
 - Diandra Asbaty, bowler
 - Tom Ashbrook, NPR personality
 - John Ashcroft, politician (Republican), U.S. Attorney General 2001–05, Missouri senator and governor
 - Darryl Ashmore, NFL tackle 1992–2002
 - James N. Ashmore, basketball coach, North Carolina, Iowa, Washington State, DePauw
 - Ed Asner, Emmy-winning actor, The Mary Tyler Moore Show, Up, Elf (born in Missouri)
 - Mary Astor, Oscar-winning actress, The Maltese Falcon, Dodsworth, Meet Me in St. Louis, The Great Lie
 - Joe Astroth, MLB catcher 1945–56
 - Ira Aten, lawman, Texas Ranger
 - Doug Atkins, defensive end for Chicago Bears 1955–66, Hall of Fame (born in Tennessee)
 - Smith D. Atkins, editor, Civil War colonel (born in New York)
 - Edith Atwater, actress, True Grit, Family Plot, The Body Snatcher
 - Richard and Florence Atwater, co-authors of Mr. Popper's Penguins
 - Steve Atwater, NFL safety 1989-99, twice Super Bowl champion with Denver Broncos
 - James T. Aubrey Jr., television executive, president of CBS
 - David Auburn, playwright, Proof
 - Jean M. Auel, author, The Clan of the Cave Bear
 - James Augustine, center for Illinois' 2005 NCAA basketball runners-up
 - Jeff Austin, mandolinist, singer
 - Lovie Austin, jazz musician (born in Tennessee)
 - Jason Avant, NFL wide receiver
 - Charles Avery, silent film actor, Keystone Kops
 - Sewell Avery, chairman of Montgomery Ward, first president of Museum of Science and Industry (born in Michigan)
 - John Avildsen, Oscar-winning film director, Rocky, Save the Tiger, Lean on Me, The Karate Kid
 - David Axelrod, political advisor to Presidents Bill Clinton and Barack Obama, author, TV commentator
 - Brendon Ayanbadejo, NFL linebacker 1999–2012
 - Marion Aye, silent-film actress
 - David Ayer, screenwriter and director, Training Day, End of Watch, Fury
 - Edward E. Ayer, benefactor and first president of Field Museum of Natural History (born in Massachusetts)
 - Harriet Hubbard Ayer, 19th Century cosmetics maven, journalist
 - Bill Ayers, founder and member of Weather Underground
 - Reiko Aylesworth, actress, Michelle Dessler on 24
 - Agnes Ayres, silent-film actress
 - Irving Azoff, music executive, head of Ticketmaster, Live Nation Entertainment
 
B
Ba–Bd
- Richard Bach, author, Jonathan Livingston Seagull
 - Charlie Bachman, football coach, Kansas State, Florida, Michigan State
 - Bill Bachrach, Olympic swim coach
 - Henry Bacon, architect of the Lincoln Memorial
 - Mary Bacon, jockey
 - Benjamin F. Bailar, United States Postmaster General 1975–78
 - Amari Bailey (born 2004), NBA basketball player[16]
 - Chantal Bailey, Olympic speed skater
 - Cory Bailey, MLB pitcher 1993–2002
 - Willis J. Bailey, Governor of Kansas 1903–05
 - Barbara Bain, actress, Mission: Impossible
 - Harold Baines, Hall of Fame outfielder, coach for Chicago White Sox (born in Maryland)
 - Butch Baird, pro golfer
 - Leah Baird, silent-film actress
 - David J. Baker, judge, U.S. Senator for 29 days (born in Connecticut)
 - David J. Baker Jr., 19th Century judge
 - Edward Dickinson Baker, U.S. Representative of Illinois, U.S. Senator of Oregon (born in England)
 - Jehu Baker, 19th Century politician, U.S. Representative (born in Kentucky)
 - Ralph Baker, Northwestern halfback in College Football Hall of Fame
 - LaVern Baker, singer in Rock and Roll Hall of Fame
 - Two Ton Baker, entertainer, radio-TV personality
 - A. J. Balaban, theater owner and showman
 - Barney Balaban, Hollywood studio chief
 - Bob Balaban, actor, Gosford Park, Close Encounters of the Third Kind, Catch-22, Waiting for Guffman
 - Frank Balasz, NFL running back 1939–45
 - Marcelo Balboa, pro soccer player
 - H.C. Baldridge, Governor of Idaho 1927–31
 - Adam Baldwin, actor, voice actor, blogger, Chuck, Full Metal Jacket, Serenity, My Bodyguard
 - Kate Baldwin, actress, singer
 - Rosecrans Baldwin, novelist, essayist
 - George Ball, diplomat, adviser to JFK and LBJ, U.S. Ambassador to United Nations
 - Carl Ballantine, magician, comedian, actor, McHale's Navy
 - Edwin Balmer, editor of Redbook magazine
 - Eddie Bane, MLB pitcher and executive
 - Ted Banker, NFL lineman 1983–91
 - Ernie Banks, 19-year infielder for Chicago Cubs, in Baseball Hall of Fame (born in Texas)
 - Kelcie Banks, boxer, 1987 Pan American Games champion
 - Jerry Barber, golfer, winner of 1961 PGA Championship
 - Curt Barclay, MLB pitcher 1957–59
 - Dave Barclay, golfer, winner of 1947 NCAA championship
 - Paris Barclay, Emmy-winning TV director and producer, In Treatment, NYPD Blue, Cold Case
 - John Bardeen, winner of two Nobel Prizes in Physics (born in Wisconsin)
 - Jesse Barfield, outfielder for Toronto Blue Jays and New York Yankees 1981–92
 - Ike Barinholtz, actor, comedian, voice actor, Mad TV, The Mindy Project, The Awesomes
 - Al Barlick, Hall of Fame baseball umpire
 - Brandon Barnes, rock musician in band Rise Against
 - Brenda C. Barnes, CEO of Sara Lee and PepsiCo
 - Edward Larrabee Barnes, architect
 - Josie Barnes, professional bowler
 - Margaret Ayer Barnes, Pulitzer Prize-winning novelist
 - Charlene Barnett, pro baseball player
 - Robert Barnett, attorney
 - Carol Ross Barney, architect
 - Dale Barnstable, basketball player for Kentucky, banned by NBA
 - Tony Barone, basketball coach, Creighton, Texas A&M and NBA's Memphis Grizzlies
 - Bea Barrett, golfer
 - The Barrett Sisters, gospel singers
 - Barbara Barrie, Oscar-nominated, Tony Award-winning actress, Barney Miller, Breaking Away
 - George Barris, auto customizer, created TV's Batmobile
 - Robert Barron, Catholic bishop
 - Ed Barrow, baseball manager, executive
 - John Barrowman, actor, singer, dancer (born in Scotland)
 - Jimmy Barry, 19th Century boxing champion
 - Norman Barry, head coach of 1925 NFL champion Chicago Cardinals, judge
 - Viola Barry, silent-film actress
 - Dick Bartell, shortstop, played in three World Series
 - William Bartholomay, owned baseball's Milwaukee and Atlanta Braves
 - Bonnie Bartlett, actress, St. Elsewhere (born in Wisconsin)
 - Peter Bartlett, actor, One Life to Live
 - Dan Barton, actor
 - Dick Barwegan, MLB outfielder 1947–54
 - Burt Baskin, co-founder of Baskin-Robbins
 - Mary Bass, editor of Ladies' Home Journal 1936–63
 - Granville Bates, actor
 - Bates Battaglia, NHL winger 1997–2008
 - Sam Battaglia, organized crime figure
 - Kenny Battle, player for four NBA teams
 - Lloyd Batts, pro basketball player
 - Hank Bauer, outfielder and manager, New York Yankees, Kansas City A's; decorated World War II U.S. Marine
 - Sybil Bauer, swimmer, gold medalist at 1924 Summer Olympics
 - Tom Baugh, center for Southern Illinois and Kansas City Chiefs
 - H. R. Baukhage, news broadcaster
 - Harry Neal Baum, ad executive, author (born in South Dakota)
 - L. Frank Baum, creator of The Wonderful Wizard of Oz, Chicago journalist (born in New York)
 - Ross Baumgarten, MLB pitcher 1978–82
 - Stan Baumgartner, MLB pitcher 1914–26 (born in Texas)
 - Harry Bay, baseball player and bandleader
 - Nora Bayes, actress, singer and songwriter, "Shine On, Harvest Moon"
 - Rick Bayless, chef and Chicago restaurateur (born in Oklahoma)
 - Beverly Bayne, silent-film actress (born in Minnesota)
 
Be–Bg
- Brea Beal, three-time Illinois Miss Basketball, 2022 NCAA champion with South Carolina
 - Jennifer Beals, actress, Flashdance, The L Word, Devil in a Blue Dress, The Book of Eli
 - Harry P. Beam, U.S. Representative 1931–42
 - Todd Beamer, heroic passenger on United 93 on 9/11 (born in Michigan)
 - Melissa Bean, U.S. Representative 2005–11
 - Arthur M. Beaupre, ambassador
 - Warren A. Bechtel, founder of Bechtel
 - Boom-Boom Beck, MLB pitcher 1924–45
 - Fred Beck, MLB player 1909–15
 - John Beck, actor, The Other Side of Midnight, Rollerball, Dallas
 - Marilyn Beck, syndicated columnist
 - George Becker, labor leader
 - Kurt Becker, lineman for Michigan and Chicago Bears
 - Rich Becker, MLB outfielder 1993–2000
 - Arnold Orville Beckman, chemist and inventor
 - Robert Todd Lincoln Beckwith, great-grandson of Abraham Lincoln
 - Hal Bedsole, tight end, College Football Hall of Fame
 - Don Beebe, wide receiver for Buffalo Bills and Super Bowl XXXI champion Green Bay Packers
 - Fred Beebe, MLB pitcher (born in Nebraska)
 - June Beebe, golfer
 - Edward Beecher, theologian and abolitionist (born in New York)
 - Chad Beguelin, Broadway lyricist, Aladdin, The Prom
 - Ken Behring, real-estate developer, owned NFL's Seattle Seahawks
 - Ed Beinor, NFL tackle 1939–42
 - Bob Bell, star of Bozo's Circus (born in Michigan)
 - Darryl M. Bell, actor, A Different World, Homeboys in Outer Space
 - Edward Price Bell, foreign correspondent
 - Josh Bell, third baseman for Baltimore Orioles 2010–11
 - Lee Phillip Bell, television personality, creator of The Young and the Restless
 - Rex Bell, actor, lieutenant governor of Nevada, husband of Clara Bow
 - William J. Bell, television producer, creator of The Bold and the Beautiful
 - Mal Bellairs, television personality (born in Wyoming)
 - Ralph Bellamy, Oscar-nominated actor, His Girl Friday, Sunrise at Campobello, Rosemary's Baby, Trading Places
 - Harry Bellaver, actor, Naked City, From Here to Eternity, Love Me or Leave Me
 - Dan Bellino, MLB umpire
 - Saul Bellow, Nobel Prize and Pulitzer Prize-winning writer, Humboldt's Gift, Seize the Day (born in Canada)
 - Louis Bellson, jazz drummer, bandleader and musician
 - James Belushi, actor, comedian, According to Jim, Saturday Night Live, Taking Care of Business, K-9
 - John Belushi, actor, comedian, Saturday Night Live, Animal House, 1941, The Blues Brothers
 - Robert Belushi, actor
 - Solon Spencer Beman, architect (born in New York)
 - Albert Benbrook, guard for Michigan, member of College Football Hall of Fame (born in Texas)
 - Bob Bender, basketball player, Indiana and Duke; head coach, Illinois State, Washington
 - Riley A. Bender, politician
 - Vincent Hugo Bendix, automotive and aviation pioneer
 - Jason Benetti, sportscaster
 - Chloe Bennet, actress, Agents of S.H.I.E.L.D.
 - Beck Bennett, comedian, Saturday Night Live
 - Doc Bennett, baseball manager and scout
 - Gary Bennett, MLB catcher 1995–2008
 - Harve Bennett, producer, The Six Million Dollar Man, Star Trek II: The Wrath of Khan
 - John W. F. Bennett, athlete and engineer
 - Paris Bennett, singer, American Idol
 - Rhona Bennett, singer, En Vogue
 - Jack Benny, iconic comedian, radio and TV personality and actor, The Jack Benny Program
 - Al Benson, music promoter in Blues Hall of Fame (born in Mississippi)
 - Jodi Benson, actress, voice actress, singer, The Little Mermaid
 - Jack Berch, singer and radio personality
 - Pete Bercich, linebacker for Notre Dame and Minnesota Vikings
 - Tom Berenger, Oscar-nominated actor, Platoon, Major League, The Big Chill, Sniper, Inception
 - Edgar Bergen, actor and ventriloquist, You Can't Cheat an Honest Man, father of Candice Bergen
 - Heinie Berger, MLB pitcher 1907–10
 - Norma Berger, pro baseball player
 - Wally Berger, MLB outfielder 1930–40, four-time All-Star
 - Emily Bergl, actress, Men in Trees, Good Night, Oscar (born in England)
 - Dave Bergman, MLB first baseman 1975-92, played for 1984 World Series champion Detroit Tigers
 - Sean Bergman, MLB pitcher 1993–2000
 - Nate Berkus, designer, television personality
 - Shelley Berman, comedian, actor, Curb Your Enthusiasm, The Best Man, Meet the Fockers
 - Carlos Bernard, actor, 24
 - Dwight Bernard, MLB pitcher 1978–82
 - Jason Bernard, actor, All of Me, While You Were Sleeping, Liar Liar
 - Ernani Bernardi, musician and politician
 - Joseph Bernardin, Cardinal Archbishop of Archdiocese of Chicago 1982-96
 - Edward Bernds, director, Return of the Fly, Queen of Outer Space
 - Edward Allen Bernero, TV writer, director, co-creator of Third Watch
 - Ken Berry, actor, F Troop, Mayberry, R.F.D., Mama's Family
 - Marcheline Bertrand, actress, mother of Angelina Jolie
 - Dick Bertell, catcher for Cubs 1960–67
 - Jay Berwanger, football star for University of Chicago, first winner of Heisman Trophy (born in Iowa)
 - Michael Beschloss, historian and author
 - William P. Bettendorf, inventor, Bettendorf, Iowa named for him
 - Gary Bettenhausen, auto racer, third place in 1980 Indianapolis 500
 - Tony Bettenhausen, auto racer, five top-10 finishes in Indy 500
 - Tony Bettenhausen Jr., auto racer, seventh place in 1981 Indy 500
 - Tom Bettis, NFL linebacker, coach
 - John Lourie Beveridge, Civil War officer and 16th Governor of Illinois (born in New York)
 - Patrick Beverley, NBA guard
 - Kamal Bey, Greco-Roman wrestler, won Junior World Title
 
Bh–Bm
- Kapri Bibbs, NFL running back
 - Bill Bidwill, owner of NFL's Arizona Cardinals 1962-2019
 - Charles Bidwill, owner of Chicago Cardinals 1933–47
 - Bret Bielema, football coach, Illinois, Arkansas, Wisconsin
 - Judy Biggert, U.S. Representative 1999–2013
 - Michael Bilandic, Mayor of Chicago 1976–79, chief justice of Illinois Supreme Court
 - Tom Billeter, basketball coach
 - George Binks, MLB outfielder 1944–48
 - Claude Binyon, journalist, screenwriter and film director
 - William Morris Bioff, organized crime figure
 - Dick Biondi, radio personality (born in New York)
 - Andrew Bird, musician
 - Chris Bisaillon, college football player
 - Frank Biscan, MLB pitcher 1942–48
 - Jerry G. Bishop, radio and TV personality
 - Joan Biskupic, journalist and author
 - William Bissell, doctor, Governor of Illinois 1857–60 (born in New York)
 - Uwe Blab, basketball player (born in Germany)
 - Black Beaver, 19th Century scout
 - Black Hawk, Sauk Indian Chief
 - Edwin Black, columnist, author of IBM and the Holocaust
 - John Charles Black, Civil War general, district attorney (born in Mississippi)
 - Jordan Black, comedy writer, actor, Halfway Home
 - Karen Black, Oscar-nominated actress, The Great Gatsby, Five Easy Pieces, Airport 1975, Family Plot
 - Quincy Black, NFL linebacker 2007–12
 - Harry Blackmun, Supreme Court justice 1970–94
 - Harry Blackstone Sr., stage magician and illusionist
 - Timothy Blackstone, railroad mogul, founder of Union Stock Yards, mayor of LaSalle, Illinois
 - Ray Blades, MLB outfielder and manager
 - Rod Blagojevich, politician (Democrat), Governor of Illinois 2003–09, imprisoned in 2012
 - Bonnie Blair, speed skater, five-time Winter Olympics gold medalist (born in New York)
 - William M. Blair, financier
 - Zach Blair, musician, Rise Against
 - John Blake, football player and head coach for Oklahoma
 - Rosa Blasi, actress, Strong Medicine, Make It or Break It, Hitz
 - Neil Blatchford, two-time Olympian speed skater
 - Tony Blazine, football player for Illinois Wesleyan and Chicago Cardinals, College Football Hall of Fame
 - Tempestt Bledsoe, actress, Vanessa Huxtable on The Cosby Show
 - Tyler Blevins, better known as "Ninja", professional gamer, Twitch streamer and YouTuber
 - Herbert Blitzstein, organized crime figure
 - Robert Bloch, writer, author of Psycho
 - John Rusling Block, U.S. Secretary of Agriculture 1981–86
 - Mary A. Blood, co-founder, Columbia College (born in New York)
 - Ike Bloom, nightclub owner during Prohibition
 - Sol Bloom, impresario, 14-term U.S. Representative of New York
 - Ossie Bluege, MLB player and manager
 - Deborah Blum, journalist and author
 - Sidney Blumenthal, journalist, aide to President Bill Clinton
 - Jimmy Blythe, musician and composer
 
Bn–Bo
- Harold P. Boas, mathematician
 - Michael Boatman, actor, writer, Spin City, China Beach, Arliss
 - Ryan Boatright, basketball player
 - Nicole Bobek, figure skater, 1995 national champion
 - Bucky Bockhorn, basketball player and broadcaster
 - Tom Bodett, ad spokesman for Motel 6
 - Samuel Bodman, politician (Republican), U.S. Secretary of Energy 2005–09
 - Tom Boerwinkle, center for Chicago Bulls 1968–78, broadcaster (born in Ohio)
 - Budd Boetticher, film director, The Tall T, The Killer Is Loose, Seven Men from Now
 - Clarence John Boettiger, journalist, son-in-law of FDR
 - Tim Bogar, MLB infielder 1993–2001 (born in Indiana)
 - Bill Bogash, pioneer of Roller Derby
 - Suzy Bogguss, country singer
 - David Boies, attorney
 - Charles Bolles, aka Black Bart, stagecoach bandit
 - Bob Boken, MLB infielder 1933–34
 - John Boles, MLB manager and executive
 - Eric Bolling, anchor at Fox Business Network, co-host of The Five
 - Don Bollweg, first baseman for 1953 World Series champion Yankees
 - Shadrach Bond, first Governor of Illinois (born in Maryland)
 - Beulah Bondi, Oscar-nominated actress, Mr. Smith Goes to Washington, It's a Wonderful Life (born in Indiana)
 - Winifred Bonfils, early 20th Century journalist (born in Wisconsin)
 - Mildred A. Bonham, journalist
 - Skeeter Bonn, country musician
 - Bonnie Lou, singer
 - Ron Bontemps, captain of 1952 Olympic gold-medal basketball team
 - Ed Boon, creator of Mortal Kombat video game
 - Levi Boone, former Mayor of Chicago of Know-Nothing Party (born in Kentucky)
 - William Borah, 33-year U.S. Senator of Idaho
 - George Bork, Northern Illinois quarterback, Hall of Fame
 - Bruce Borland, golf course designer
 - Alex Borstein, actress, Family Guy, The Marvelous Mrs. Maisel
 - Tom Bosley, actor, Happy Days, Father Dowling Mysteries, Murder, She Wrote
 - Roger Bossard, groundskeeper
 - Cathy Boswell, basketball player
 - Jim Bottomley, Hall of Fame first baseman, 1928 MVP, two-time World Series champion
 - Chesa Boudin, lawyer, District Attorney of San Francisco 2020-22 (born in New York)
 - Lou Boudreau, Hall of Fame shortstop, manager, broadcaster, 1948 MVP and World Series champion
 - Peter Bourjos, MLB outfielder 2010-19
 - Mel Bourne, Oscar-nominated art designer
 - Dick Boushka, 1956 Olympic basketball gold medalist
 - Henry S. Boutell, U.S. Representative 1897–1911 (born in Massachusetts)
 - Charles Bowden, non-fiction author, journalist, essayist
 - Michael Bowden, pitcher for Boston Red Sox 2008–12
 - Louise DeKoven Bowen, suffragist, philanthropist
 - Matt Bowen, safety for four NFL teams
 - Roger Bowen, actor, M*A*S*H, charter member of Second City (born in Rhode Island)
 - Jon Bowermaster, adventurer, National Geographic oceans expert
 - Ken Bowman, center for Super Bowl I and II champion Green Bay Packers
 - Charles Box, first African-American mayor of Rockford
 - Bruce Boxleitner, actor, science fiction novelist, Babylon 5, Scarecrow and Mrs. King, the Tron films
 - Charles Boyce, syndicated cartoonist (born in Mississippi)
 - William D. Boyce, founder of Boy Scouts of America (born in Pennsylvania)
 - Guy Boyd, actor, Streamers, Body Double
 - William W. Boyington, architect of Chicago Water Tower, mayor of Highland Park (born in Massachusetts)
 - Ronnie Boykins, jazz musician
 - Lara Flynn Boyle, actress, The Practice, Twin Peaks, The Temp, Men in Black II (born in Iowa)
 - Walter J. Boyne, Air Force pilot, author, historian, director of National Air and Space Museum
 - Megan Bozek, hockey player, 2014 Winter Olympics silver medalist
 
Br–Bt
- Emil J. Brach, candy mogul
 - Helen Brach, candy heiress, presumed murder victim (born in Ohio)
 - Ray Bradbury, science-fiction author, Fahrenheit 451, The Illustrated Man, Something Wicked This Way Comes
 - Harold Bradley Jr., football player and actor
 - Lydia Moss Bradley, philanthropist, founder of Bradley University (born in Indiana)
 - Phil Bradley, college football and pro baseball player (born in Indiana)
 - Morris Bradshaw, wide receiver for Oakland Raiders 1974–81
 - Sufe Bradshaw, actress, Veep
 - James B. Bradwell, judge (born in England)
 - Myra Bradwell, state's first female lawyer (born in Vermont)
 - Ed Brady, linebacker for three NFL teams
 - James Brady, advisor and White House press secretary to Ronald Reagan
 - Daniel Brainard, surgeon
 - Neville Brand, actor, D.O.A., Love Me Tender, The Untouchables, Birdman of Alcatraz
 - Mark Staff Brandl, art critic, reviewer for Art in America
 - Jonathon Brandmeier, radio personality (born in Wisconsin)
 - Marlon Brando, Oscar-winning actor, The Godfather, Last Tango in Paris, Apocalypse Now (born in Nebraska)
 - Mac Brandt, actor, Prison Break
 - Erik Brann, guitarist with Iron Butterfly
 - Hugh Brannum, TV personality, Captain Kangaroo
 - Oscar Brashear, jazz musician
 - Cameron Brate, tight end for Tampa Bay Buccaneers
 - Zeke Bratkowski, NFL quarterback and coach
 - Andre Braugher, actor, Homicide: Life on the Street, Hack, Men of a Certain Age, Brooklyn Nine-Nine
 - Ben Braun, basketball coach, Rice, Cal, Eastern Michigan
 - Carol Moseley Braun, first African-American female U.S. Senator
 - Tamara Braun, soap opera actress
 - Anthony Braxton, jazz musician
 - Henry Skillman Breckinridge, attorney in Charles Lindbergh kidnap case, Olympic fencer
 - Brent Brede, MLB outfielder 1996–98
 - Richard L. Breen, Oscar-winning screenwriter, Titanic, Niagara, PT 109
 - Sidney Breese, judge, U.S. Senator, advocate of Illinois Central railroad
 - Buddy Bregman, music arranger
 - Edward A. Brennan, president and CEO of Sears, Roebuck & Co. 1980–95
 - Kathleen Brennan, songwriter, producer, wife of Tom Waits
 - Josh Brent, nose tackle for Dallas Cowboys
 - Jerry Bresler, songwriter, "Five Guys Named Moe"
 - Carl Brettschneider, NFL linebacker 1956–63
 - Jim Brewer, basketball player, 1972 Olympics and Cleveland Cavaliers
 - Ralph Breyer, swimmer, 1924 Olympic gold medalist
 - Jack Brickhouse, Hall of Fame baseball broadcaster
 - Paul Brickman, writer-director, Risky Business, Men Don't Leave
 - Donald Briggs, actor
 - Nancy Brinker, ambassador, winner of Presidential Medal of Freedom
 - John Briscoe, pitcher for Oakland A's 1991–96
 - Nicole Briscoe, sportscaster, Miss Teen Illinois 1998 (born in Wisconsin)
 - Frank Brisko, auto racer, 12 times in Indianapolis 500
 - Paul Brittain, actor, comedian, cast member on Saturday Night Live
 - Frederick A. Britten, 22-year U.S. Representative
 - David Broder, journalist, author, 1973 Pulitzer Prize-winning Washington Post columnist
 - Jayne Brook, actress, Chicago Hope, The District
 - Charles W. Brooks, World War I veteran, U.S. Senator of Illinois 1940–49
 - Gwendolyn Brooks, poet (born in Kansas)
 - Phil Brooks, professional wrestler and WWE Champion under ring name "CM Punk"
 - Rachel Brosnahan, Emmy-winning actress, The Marvelous Mrs. Maisel (born in Wisconsin)
 - Maya-Camille Broussard, chef and television personality
 - Bill Brown, fullback for Minnesota Vikings, four-time Pro Bowl selection
 - Bobbi Brown, CEO of Bobbi Brown Cosmetics
 - Buck Brown, cartoonist
 - Chelsea Brown, actress, Rowan & Martin's Laugh-In
 - Chris Brown, NFL running back 2003–09
 - Corwin Brown, defensive back, coach for New England Patriots
 - Dee Brown, guard for Illinois 2005 NCAA runners-up, Big Ten Player of the Year
 - Dee Brown, author, Bury My Heart at Wounded Knee, librarian and alumnus of Illinois (born in Louisiana)
 - Emil Brown, MLB outfielder 1997–2009
 - Jason Brown, figure skater, 2015 U.S. champion
 - Jesse Brown, U.S. Secretary of Veterans' Affairs 1993–97 (born in Michigan)
 - Lorenzo Brown, player in Israeli Basketball Premier League
 - Mike Brown, NHL wing 2007-16
 - Nancy Elizabeth Brown, highly decorated U.S. Navy Vice Admiral
 - Oscar Brown, songwriter
 - Patrick Brown, NFL offensive tackle 2009-13
 - Peter Brown, songwriter, "Material Girl"
 - Roy Brown, children's entertainer, The Bozo Show, Garfield Goose and Friends (born in Arizona)
 - Sergio Brown, NFL safety 2010-16
 - Shannon Brown, guard for eight NBA teams
 - Theotis Brown, NFL running back 1979–83
 - Tony Brown, NBA player and coach
 - Warren Brown, early 20th Century sportswriter
 - Orville Hickman Browning, completed U.S. Senate term of Stephen A. Douglas, U.S. Secretary of Interior (born in Kentucky)
 - David Bruce, actor, The Mad Ghoul, Lady on a Train
 - Hank Bruder, NFL guard 1931–39, Green Bay Packers Hall of Fame
 - Don Brumm, NFL defensive tackle 1963–72
 - Avery Brundage, athlete, decathlon and pentathlon, President of International Olympic Committee 1952–72
 - Liz Brunner, television journalist, 1979 Miss Illinois
 - Doug Bruno, women's basketball coach, DePaul University, 2012 U.S. Olympic team
 - Hal Bruno, political journalist
 - Jalen Brunson, NBA player, two-time NCAA champion with Villanova
 - Milton Brunson, gospel musician
 - Charles W. Bryan, mayor of Lincoln, Nebraska 1915–17 and two-term Governor of Nebraska
 - Johnny Bryan, pro football player and team owner
 - Mary Baird Bryan, attorney and suffragist
 - William Jennings Bryan, politician (Democrat), U.S. Secretary of State 1913–15, presidential candidate 1896, 1900, 1908
 - Corbin Bryant, NFL player for Buffalo Bills
 - Em Bryant, guard for 1969 NBA champion Boston Celtics
 - Kelci Bryant, diver, silver medalist at 2012 London Olympics
 - Rosalyn Bryant, sprinter, silver medalist at 1976 Summer Olympics
 - Bob Bryar, musician, My Chemical Romance drummer
 
Bu–Bz
- Ray Buchanan, NFL defensive back 1993–2004
 - Ellsworth B. Buck, U.S. Representative 1944-49
 - Frank Buck, hunter, zookeeper, actor (born in Texas)
 - Bob Buckhorn, mayor of Tampa, Florida 2011-19
 - The Buckinghams, pop group, "Kind of a Drag"
 - Tom Buckingham, film director
 - Quinn Buckner, basketball player, winner of high school, NCAA, Olympic and NBA championships
 - John Carl Buechler, horror movie writer/director, special effects artist
 - Doug Buffone, linebacker for Chicago Bears, sportscaster (born in Pennsylvania)
 - John Buford, Civil War general (born in Kentucky)
 - Napoleon Bonaparte Buford, Civil War general (born in Kentucky)
 - Bryan Bulaga, offensive tackle for Green Bay Packers
 - Richard Bull, actor, Little House on the Prairie, Voyage to the Bottom of the Sea
 - Storm Bull, musician
 - John Whitfield Bunn, financier, treasurer of Abe Lincoln campaign (born in New Jersey)
 - Elbridge Ayer Burbank, artist
 - Horatio C. Burchard, director of U.S. Mint 1879–85, U.S. Representative 1869–79 (born in New York)
 - Jacob Burck, cartoonist for Chicago Sun-Times 1938–1982 (born in Poland)
 - Hannibal Buress, stand-up comedian, actor, The Eric Andre Show, Broad City
 - Anne M. Burke, Illinois Supreme Court justice, co-founder of Special Olympics
 - Bobby Burke, MLB pitcher 1927–37
 - Edward M. Burke, politician (Democrat), Chicago alderman 1969-2023
 - Johnny Burke, lyricist in Songwriters Hall of Fame (born in California)
 - Kathleen Burke, actress, Island of Lost Souls, The Lives of a Bengal Lancer
 - Leo Burnett, advertising executive
 - W. R. Burnett, novelist, screenwriter, Little Caesar, Nobody Lives Forever, High Sierra (born in Ohio)
 - Smiley Burnette, country singer and musician, Western actor
 - Daniel H. Burnham, architect, Chicago city planner (born in New York)
 - Heather Burns, actress, Bored to Death, Miss Congeniality and its sequel
 - Ronnie Burns, actor, Burns and Allen
 - Pete Burnside, pitcher for six MLB teams
 - Hedy Burress, actress, Foxfire, Boston Common
 - Roland Burris, U.S. Senate appointee to succeed Barack Obama 2009-10, Illinois Attorney General
 - Edgar Rice Burroughs, author, creator of Tarzan
 - Cheryl Burton, television journalist
 - Ed Busch, MLB infielder 1943–45
 - Samuel T. Busey, Civil War general, politician (born in Indiana)
 - Homer Bush, MLB infielder 1997-2004, member of 1998 World Series champion New York Yankees
 - Fred A. Busse, postmaster, Mayor of Chicago 1907–11
 - Cheri Bustos, U.S. Representative 2013-23
 - Fanny Butcher, influential critic and editor
 - Mike Butcher, MLB pitching coach
 - Drew Butera, catcher for 2015 World Series champion Kansas City Royals
 - Dick Butkus, Hall of Fame football player for Illinois and Chicago Bears, actor
 - Luke Butkus, NFL assistant coach
 - Brett Butler, MLB outfielder 1981–97 (born in California)
 - Daws Butler, voice of Yogi Bear, other cartoon characters (born in Ohio)
 - Jerry Butler, singer in Rock and Roll Hall of Fame
 - Michael Butler, theatrical producer
 - Paul Butler, polo champion, founder of Oak Brook and Butler National Golf Club
 - Robert L. Butler, 50-year mayor of Marion, Illinois
 - Paul Butterfield, musician in Blues Hall of Fame and Rock and Roll Hall of Fame
 - Dave Butz, defensive lineman for Washington Redskins, St. Louis Cardinals, two-time Super Bowl champion
 - Ernie Byfield, hotelier, founder of The Pump Room
 - Will Bynum, NBA point guard 2006–15
 - John Byrum, screenwriter and director, Heart Beat, Duets, The Razor's Edge
 - Tim Byrdak, pitcher for five MLB teams
 - Jane Byrne, first female Mayor of Chicago
 - Jeff Bzdelik, head coach, Denver Nuggets, Air Force, Colorado, Wake Forest
 
C
Ca–Cd
- Frances Xavier Cabrini, nun, missionary, canonized saint (born in Austria)
 - Leon Cadore, MLB player 1915–24, pitched a record 26 innings in one game
 - Calvin Brainerd Cady, musician and professor
 - Jack Cafferty, political commentator for CNN 2005–12
 - Beth Cahill, comedian
 - Leo Cahill, CFL coach and executive
 - Jonathan Cain, musician with Rock and Roll Hall of Fame band Journey
 - Frank Calabrese Sr., organized crime figure
 - Nicholas Calabrese, organized crime figure
 - Jessica Calalang, figure skater
 - Ben F. Caldwell, banker, U.S. Representative 1899–1905
 - L. Scott Caldwell, actress, Lost, Queens Supreme
 - Corky Calhoun, NBA forward 1972–80
 - Frank Caliendo, comedian
 - Earnest Elmo Calkins, advertising executive
 - Bill Callahan, head coach of Oakland Raiders 2002–03 and University of Nebraska 2004–07
 - Frances Callier, actress, comedian, Hannah Montana
 - Sarah Wayne Callies, actress, The Walking Dead
 - Ann Hampton Callaway, singer and actress
 - John Callaway, public television journalist
 - Liz Callaway, singer and actress
 - Chris Calloway, NFL wide receiver 1990–2000
 - George H. Cameron, World War I general
 - Julia Cameron, writer, second wife of Martin Scorsese
 - Bruce Campbell, MLB outfielder 1930–42
 - Danielle Campbell, actress, The Originals, Tell Me a Story
 - Heather Anne Campbell, comedian
 - Louise Campbell, actress, The Star Maker, Night Club Scandal
 - Tom Campbell, U.S. Representative in California 1989–2001
 - Marvin Camras, inventor
 - Larry Canada, NFL running back 1978–81
 - Tony Canadeo, halfback for Green Bay Packers 1941–52, Pro Football Hall of Fame
 - Vincent Canby, film critic, New York Times
 - Glenn Canfield Jr., metallurgist and businessman
 - Joe Cannon, politician (Republican), Speaker of the House 1903–11 (born in North Carolina)
 - Kay Cannon, screenwriter and director, Pitch Perfect, Blockers, Cinderella
 - Jim Cantalupo, CEO of McDonald's Corporation 1991–2004
 - Shorty Cantlon, runner-up in 1930 Indianapolis 500, killed in 1947 race
 - Homaro Cantu, restaurateur (born in Washington)
 - Dominique Canty, pro basketball player
 - Al Capone, gangster, bootlegger, boss of Chicago Outfit, subject of Capone, The Untouchables (born in New York)
 - Frank Capone, organized crime figure, brother of Al (born in New York)
 - John Caponera, comedian, actor, The Good Life
 - Antonio "Tony Bananas" Caponigro, consigliere of Angelo Bruno in Philadelphia crime family
 - Buzz Capra, MLB pitcher 1971–77
 - The Caravans, gospel singers
 - Perry Caravello, comedian, skateboarder, star of Windy City Heat
 - Harry Caray, Hall of Fame broadcaster for Chicago White Sox and Chicago Cubs (born in Missouri)
 - Brian Cardinal, forward for six NBA teams
 - Steve Carell, actor and comedian, Second City alumnus (born in Massachusetts)
 - Gabe Carimi, All-American and NFL football player
 - Thomas Carlin, Governor of Illinois 1838–42; Carlinville named for him (born in Kentucky)
 - Amy Carlson, actress, Third Watch, Blue Bloods
 - Hal Carlson, MLB pitcher 1917–30
 - Mark Carlson, MLB umpire
 - John P. Carmichael, sportswriter
 - Chuck Carney, football and basketball All-American
 - Sue Carol, talent agent, wife of Alan Ladd
 - J. C. Caroline, halfback for Illinois, defensive back for Chicago Bears
 - Ed Carpenter, auto racer, runner-up in 2018 Indianapolis 500, pole sitter 2013, 2014, 2018
 - John Alden Carpenter, composer
 - Philo Carpenter, pharmacist
 - John Carpino, president of MLB's Los Angeles Angels
 - Allan Carr, producer, Grease, Saturday Night Fever
 - Charmian Carr, actress, The Sound of Music
 - Darleen Carr, actress, The Smith Family, The Beguiled
 - Marian Carr, actress, San Quentin, Ring of Fear
 - Chico Carrasquel, shortstop for White Sox, first Latin starter in All-Star Game (born in Venezuela)
 - Mark Carreon, MLB player 1987–96
 - Connor Carrick, NHL defenseman
 - Janet Carroll, actress, Risky Business, Family Business
 - Lucille Carroll, Hollywood studio executive
 - Jenny Lou Carson, sharpshooter, country music singer, in Nashville Songwriters Hall of Fame
 - Terrence C. Carson, actor, voice actor, Living Single, Star Wars: Clone Wars
 - Bryan Carter, musician, 2023 Tony Award winner for Some Like It Hot (born in Missouri)
 - Johnny Carter, singer, The Flamingos
 - Myra Carter, stage actress
 - Maurice Carthon, NFL running back and coach
 - James Cartwright, USMC general, Vice Chairman of the Joint Chiefs of Staff
 - Peter Cartwright, revivalist (born in Virginia)
 - William Frank Carver, Wild West sharpshooter and showman
 - Marty Casey, musician
 - Robert J. Casey, decorated soldier and correspondent
 - Zadok Casey, founder of Mount Vernon, Illinois, lieutenant governor, U.S. Representative (born in Georgia)
 - Vera Caspary, author, Laura
 - Bill Cassidy, U.S. Senator of Louisiana
 - Claudia Cassidy, music and drama critic
 - Dan Castellaneta, actor, The Simpsons, The Pursuit of Happyness, Happy Feet
 - Latham Castle, judge, Illinois Attorney General 1952-59
 - John Castino, MLB infielder 1979–84, 1979 A.L. Rookie of the Year
 - Anthony Castonzo, offensive lineman for Indianapolis Colts
 - Frank Catalano, saxophonist
 - Wayne Catalano, horse racing trainer
 - George Catavolos, football coach
 - Tamika Catchings, basketball player, winner of NCAA, WNBA and Olympic championships (born in New Jersey)
 - Mark Catlin Sr., football coach for Iowa 1906–08
 - Helen Tunnicliff Catterall, lawyer, historian
 - Phil Cavarretta, player and manager for Chicago Cubs, 1945 National League MVP
 
Ce–Ch
- Anton Cermak, politician (Democrat), assassinated Mayor of Chicago 1931–33 (born in Eastern Europe)
 - Eugene Cernan, astronaut, commander of Apollo 17
 - JoBe Cerny, actor, voice of Pillsbury Doughboy
 - Jackie Cerone, mobster
 - Exene Cervenka, singer with punk rock band X
 - Peter Cetera, singer and songwriter, "Glory of Love"
 - Tom T. Chamales, novelist
 - Wes Chamberlain, MLB outfielder 1990–95
 - John Chambers, Oscar-winning makeup artist
 - Gower Champion, multiple Tony Award-winning dancer, choreographer and actor, Show Boat, Carnival, Hello, Dolly!
 - Chance the Rapper, Grammy-winning hip-hop artist
 - Frank Chance, Hall of Fame first baseman for Cubs (born in California)
 - John Chancellor, television journalist, NBC news anchor
 - Bill Chandler, basketball coach for Marquette 1930–51
 - Gene Chandler, singer, "The Duke of Earl"
 - George Chandler, actor
 - Kyle Chandler, Emmy-winning actor, Friday Night Lights, Argo, Carol, The Wolf of Wall Street
 - Raymond Chandler, author and screenwriter, The Big Sleep, Double Indemnity, The Long Goodbye, Farewell, My Lovely
 - Melanie Chandra, actress, Code Black
 - Jay Chandrasekhar, actor, comedian, film director
 - Octave Chanute, aviation pioneer
 - John Putnam Chapin, Mayor of Chicago 1846–47 (born in Vermont)
 - Brenda Chapman, animator and film director, The Prince of Egypt, Brave
 - Charles Chapman, mayor of Fullerton, California, founder of Chapman College
 - Pleasant T. Chapman, educator, lawyer, U.S. Representative
 - Ray Chapman, infielder for Cleveland Indians 1912–20 (born in Kentucky)
 - Joe Charboneau, outfielder with Cleveland Indians 1980–82
 - Ezzard Charles, boxing champion (born in Georgia)
 - Nick Charles, broadcaster for CNN
 - Hobart Chatfield-Taylor, author
 - Wayne Chatfield-Taylor, commerce and treasury secretary to FDR
 - Cheap Trick, band from Rockford in Rock and Roll Hall of Fame
 - Maurice Cheeks, basketball Hall of Famer and NBA coach
 - Barry Cheesman, pro golfer
 - Chris Chelios, Hall of Fame hockey player for Detroit Red Wings and Chicago Blackhawks
 - Erwin Chemerinsky, law professor
 - Steve Chen, co-creator of YouTube (born in Taiwan)
 - Virginia Cherrill, actress, City Lights, wife of Cary Grant
 - Matthew A. Cherry, screenwriter and director
 - Steve Cherundolo, head coach, Los Angeles FC soccer club
 - Leonard Chess, music executive, founder of Chess Records (born in Poland)
 - Lisa Chesson, Olympic hockey player
 - Augustus Louis Chetlain, Civil War general (born in Missouri)
 - Elizabeth Pickett Chevalier, tobacco heiress, silent-film director and writer
 - Chicago, musical group, Rock and Roll Hall of Fame
 - Judy Chicago, feminist artist and author
 - Gery Chico, lawyer, politician, chairman of Illinois State Board of Education
 - Brad Childress, head coach of Minnesota Vikings 2006–10
 - The Chi-Lites, R & B group, "Have You Seen Her"
 - Carl R. Chindblom, Cook County attorney, U.S. Representative 1919–33
 - Bob Chinn, restaurateur (born in Minnesota)
 - Burnett M. Chiperfield, veteran of Spanish–American War, U.S. Representative
 - Robert B. Chiperfield, veteran of World War I, U.S. Representative
 - Harry Chiti, catcher for four MLB teams
 - Whitney Chitwood, stand-up comedian
 - Kim Chizevsky-Nicholls, IFBB pro bodybuilder
 - Anna Chlumsky, actress, My Girl, Veep, Inventing Anna
 - Clyde L. Choate, politician, World War II Medal of Honor recipient
 - Richard Christiansen, Chicago theater critic
 - Greta Christina, atheist blogger, speaker, and author
 - William Christopher, actor, M*A*S*H
 - June Christy, big-band singer
 - Amy Chua, professor at Yale Law School, author of World on Fire
 - Kenneth Choi, actor, Sons of Anarchy, The Wolf of Wall Street
 - Marguerite S. Church, psychologist, six-term U.S. Representative, widow of Ralph Church
 - Ralph E. Church, lawyer, U.S. Representative 1935–49
 
Ci–Cn
- Tony Cingrani, MLB pitcher 2012-18
 - Gertrude Claire, silent-film actress
 - Bud Clancy, MLB first baseman 1924–34
 - Jim Clancy, pitcher for Toronto Blue Jays and Houston Astros
 - Richard Clarida, economist, Vice Chair of the Federal Reserve 2018-22
 - Bridgetta Clark, silent-film actress
 - Colbert Clark, screenwriter and director
 - Danny Clark, linebacker for five NFL teams
 - Dee Clark, singer, "Raindrops"
 - George Clark, football coach, Kansas State, Nebraska
 - Keon Clark, NBA player 1998-2004
 - Mark Clark, pitcher for five MLB teams
 - Mark W. Clark, World War II general (born in South Carolina)
 - Randy Clark, NFL lineman 1980–87
 - Wesley Clark, U.S. Army general, Presidential Medal of Freedom recipient, 2004 presidential candidate
 - Wilbur Clark, original owner of Desert Inn hotel in Las Vegas
 - Alden W. Clausen, president of World Bank and Bank of America
 - Otis Clay, musician in Blues Hall of Fame
 - Ethel Clayton, early 20th Century actress
 - David Clennon, actor, The Thing, Star 80, Being There
 - James Cleveland, Grammy-winning gospel singer
 - Nathaniel Clifton, player for New York Knicks, Harlem Globetrotters
 - Hillary Clinton, attorney and politician, First Lady (1993–2000), U.S. Senator of New York (2000–2009) and U.S. Secretary of State; 2016 Democratic presidential nominee
 - William H. Clothier, Oscar-nominated cinematographer
 
Coa–Com
- Ed Coady, quarterback of first Notre Dame victory, 1888
 - Pat Coady, Notre Dame quarterback, 1892
 - Henry Ives Cobb Jr., artist and architect
 - Junie Cobb, musician and bandleader (born in Arkansas)
 - Silas B. Cobb, industrialist (born in Vermont)
 - Ali Cobrin, actress, American Reunion, Lap Dance
 - Annie Swan Coburn, art collector
 - Catherine Amanda Coburn, journalist, editor
 - Diablo Cody, Oscar-winning screenwriter, Juno
 - Eleanor Coen, artist
 - Ryan Cohan, jazz pianist
 - Aaron Cohen, judoka
 - Irwin Cohen, Olympic judoka
 - Paul Cohen, music producer
 - Selma Jeanne Cohen, dance teacher, historian
 - Steve Cohen, Olympic judoka
 - David Cohn, American-Israeli basketball player
 - Sonny Cohn, trumpeter
 - Mark Cohon, commissioner of Canadian Football League 2007-15
 - Bryan Colangelo, NBA executive
 - Jerry Colangelo, chairman of USA Basketball, owned Arizona Diamondbacks and Phoenix Suns
 - Stephen Colbert, comedian, alumnus of Northwestern and Second City (born in Washington, D.C.)
 - Freddy Cole, jazz musician, brother of Nat King Cole
 - Gary Cole, actor, The Brady Bunch Movie, Office Space, Midnight Caller, Fatal Vision, Family Guy
 - Ike Cole, jazz musician, brother of Nat King Cole
 - James M. Cole, U.S. Deputy Attorney General under President Barack Obama
 - Nat King Cole, singer, musician and actor, Grammy Lifetime Achievement Award (born in Alabama)
 - Robert MacFarlan Cole III, chemical engineer, inventor, and author
 - Bessie Coleman, aviator
 - Ellis Coleman, Greco-Roman wrestler
 - Gary Coleman, actor, Arnold Jackson on Diff'rent Strokes
 - Gerald Coleman, ice hockey goalie
 - John Coleman, TV weather forecaster (born in Texas)
 - Tevin Coleman, running back for Atlanta Falcons (born in Georgia)
 - Edward Coles, secretary to James Madison, second Governor of Illinois (born in Virginia)
 - Michael Colgrass, winner of 1978 Pulitzer Prize for music
 - Ned Colletti, general manager for Los Angeles Dodgers 2006–14
 - Harold R. Collier, mayor of Berwyn, 18-year U.S. Representative
 - Lou Collier, MLB player 1997–2004
 - Bob Collins, radio personality (born in Florida)
 - Cardiss Collins, politician (Democrat), U.S. Representative 1973–97 (born in Missouri)
 - Chris Collins, basketball head coach for Northwestern
 - Doug Collins, NBA and Olympic basketball player, head coach of four NBA teams, TV commentator
 - Eddie Collins, Hall of Fame infielder, manager for White Sox (born in New York)
 - George W. Collins, U.S. Representative 1970–72
 - Jimmy Collins, NBA player for Chicago Bulls, head coach at Chicago State 1996-2010 (born in New York)
 - Julia Collins, 20-time winner on TV's Jeopardy!
 - Kreigh Collins, tennis player, 1899 US Open semi-finalist
 - Marva Collins, educator (born in Alabama)
 - Phil Collins, pitcher for three MLB teams
 - Sherron Collins, NBA point guard
 - James Colosimo, organized crime figure
 - George Radcliffe Colton, U.S. Representative from Nebraska, governor of Puerto Rico
 - Harvey Doolittle Colvin, city treasurer, Mayor of Chicago 1873–75 (born in New York)
 - Ruth Johnson Colvin, literacy activist, Presidential Medal of Freedom
 - Shawn Colvin, Grammy-winning singer and songwriter (born in South Dakota)
 - Harry Combes, 20-year head basketball coach at Illinois
 - Charles Comiskey, founding owner of Chicago White Sox, member of baseball Hall of Fame
 - Chuck Comiskey, owner of White Sox 1956–61
 - Grace Comiskey, owner of White Sox 1939–56
 - J. Louis Comiskey, owner of White Sox 1931–39
 - Common, Oscar, Emmy and Grammy-winning rap musician, songwriter, producer, actor
 - J. T. Compher, NHL center, 2022 Stanley Cup champion with Colorado Avalanche
 - Ann Compton, television journalist
 
Con–Coz
- Douglas Conant, CEO of the Campbell Soup Company
 - Kate Condon, opera singer
 - Zez Confrey, musician
 - Edwin H. Conger, ambassador, congressman, Civil War officer
 - Jocko Conlan, Hall of Fame baseball umpire
 - Darlene Conley, actress, The Bold and the Beautiful
 - Mike Conley Sr., athlete, gold medalist, triple jump, 1992 Barcelona Olympics
 - Bart Conner, gymnast, gold medalist, parallel bars, 1984 Los Angeles Olympics
 - Mike Connolly, gossip columnist
 - George Connor, Hall of Fame offensive tackle and linebacker for Chicago Bears
 - Jimmy Connors, tennis player, five-time US Open champion, twice Wimbledon champion, ranked No. 1 in world
 - Robert Conrad, actor, Hawaiian Eye, The Wild Wild West, Baa Baa Black Sheep, Palm Springs Weekend
 - Bill Conroy, MLB catcher 1935–44
 - Sean Considine, safety for five NFL teams
 - Hollis Conway, high jumper, two-time Olympic medalist
 - Brian Cook, forward for Illinois and five NBA teams, 2003 Big Ten Player of the Year
 - Daniel Pope Cook, lawyer, publisher, state's first attorney general; Cook County named for him (born in Kentucky)
 - Elisha Cook Jr., character actor, The Maltese Falcon, Shane, The Killing, The Big Sleep
 - John Pope Cook, Civil War general, mayor of Springfield
 - Toi Cook, NFL defensive back 1987-97, played for Super Bowl XXIX champion San Francisco 49ers
 - Sam Cooke, singer, "You Send Me", recipient of Grammy Lifetime Achievement Award (born in Mississippi)
 - William F. Coolbaugh, 19th Century banker (born in Pennsylvania)
 - Jack Cooley, pro and Notre Dame basketball player
 - Ron Coomer, infielder for Minnesota Twins, sportscaster
 - Sam Coonrod, MLB pitcher
 - Cynthia Cooper, Hall of Fame basketball player and coach, four-time WNBA champion
 - D. J. Cooper, player in Israeli Basketball Premier League
 - Jerome Cooper, drummer
 - Job Adams Cooper, Governor of Colorado 1889–91
 - Martin Cooper, inventor of modern cell phone
 - Maxine Cooper, actress, Kiss Me Deadly
 - Wyllis Cooper, radio writer, screenwriter
 - Ira C. Copley, publisher, U.S. Representative 1911–23
 - Chet Coppock, sportscaster
 - Ben Corbett, film actor
 - George Corbett, running back for Chicago Bears 1932–38
 - Virginia Lee Corbin, actress (born in Arizona)
 - Tom Corcoran, politician (Republican), four-term U.S. Representative
 - Kevin Cordes, NCAA champion swimmer
 - Billy Corgan, musician for alternative rock band Smashing Pumpkins
 - Bartlett Cormack, playwright and screenwriter
 - Jim Cornelison, tenor, anthem singer
 - Don Cornelius, television host, producer, creator of Soul Train
 - Lillian Cornell, singer and actress
 - Frank Cornish, NFL lineman 1990–95
 - Frank J. Corr, alderman, acting Mayor of Chicago 1933
 - Charles Correll, co-creator and star of Amos 'n' Andy
 - Eldzier Cortor, artist (born in Virginia)
 - Joe Corvo, NHL player 2002-14
 - Dave Corzine, center for DePaul and Chicago Bulls
 - Jon Corzine, CEO of Goldman Sachs, U.S. Senator of New Jersey 2001–06, Governor 2006–10
 - Pete Cosey, guitarist for Miles Davis
 - Jerry F. Costello, politician (Democrat), U.S. Representative 1988–2013
 - Neal Cotts, pitcher for 2005 World Series champion White Sox
 - John Coughlin, politician (Democrat), Chicago alderman 1893–1938
 - Johnny Coulon, boxer, bantamweight champion 1910–14 (born in Canada)
 - Jim Courtright, Wild West gunfighter, lawman
 - Kirk Cousins, quarterback for Minnesota Vikings
 - Bryan Cox, linebacker for Miami Dolphins and Super Bowl XXXVI champion New England Patriots
 - Jim Cox, MLB player 1973–76
 - John H. Cox, businessman, politician
 - Sonny Cox, musician, coach (born in Ohio)
 - Wally Cox, actor, Mister Peepers, Underdog (born in Michigan)
 - Dale Coyne, auto racing driver and executive
 - Kendall Coyne, hockey player, silver medalist at 2014 Winter Olympics
 - Chief Keef (Keith Cozart), rapper, singer, songwriter and record producer
 - James Gould Cozzens, novelist, By Love Possessed
 
Cr–Cz
- Wallace Craig, experimental psychologist, behavior scientist (born in Canada)
 - Yvonne Craig, actress, Batman, Kissin' Cousins
 - Dan Crane, dentist, politician (Republican), U.S. Representative 1979-85
 - Phil Crane, politician (Republican), U.S. Representative 1969–2005
 - Cindy Crawford, supermodel, cosmetics entrepreneur, actress and TV personality, House of Style
 - Corey Crawford, goaltender for Chicago Blackhawks 2006-20, two-time Stanley Cup champion (born in Canada)
 - Danny Crawford, NBA referee
 - Drew Crawford, basketball player in the Israeli Basketball Premier League
 - Ellen Crawford, actress, ER
 - Jim Crawford, MLB pitcher 1973–78
 - Oliver Crawford, blacklisted screenwriter
 - Dewitt Clinton Cregier, engineer, mason, Mayor of Chicago 1889–91 (born in New York)
 - John Crerar, industrialist, railroad director (born in New York)
 - Jim Crews, basketball player for 1976 NCAA champion Indiana, head coach for Evansville, Army, St. Louis
 - Michael Crichton, author, screenwriter, director, Jurassic Park, ER, Westworld, Rising Sun, Coma, Disclosure
 - Michele Crider, opera singer
 - Fritz Crisler, football head coach for Michigan, Minnesota, Princeton
 - John P. Cromwell, submarine commander
 - James Cronin, physicist, 1980 Nobel Prize
 - Kevin Cronin, lead vocalist for REO Speedwagon
 - Shawn Cronin, NHL defenseman 1988–95
 - Casey Crosby, pitcher for Detroit Tigers 2012
 - Jim Crowley, halfback for Notre Dame, NFL player, Michigan State coach, College Football Hall of Fame
 - Henry Crown, businessman, philanthropist
 - Lester Crown, businessman, philanthropist
 - Arthur Crudup, musician, "That's All Right" (born in Mississippi)
 - Dave Cruikshank, speed skater, four-time Olympian
 - The Cryan' Shames, rock band
 - Bob Cryder, NFL guard 1978–86
 - Walt Cudzik, NFL center 1954–64
 - Melinda Culea, actress, Brotherly Love, Knots Landing, The A-Team
 - John Cullerton, politician
 - William J. Cullerton, decorated World War II pilot
 - Philip Hart Cullom, admiral
 - Shelby Moore Cullom, lawyer, Governor of Illinois 1877–1883, U.S. Senator 1883–1913 (born in Kentucky)
 - Edith Cummings, golfer, 1923 U.S. Women's Amateur champion
 - Terry Cummings, player for DePaul and seven NBA teams, 1983 NBA Rookie of the Year
 - Lester Cuneo, silent-film actor
 - Barbara Flynn Currie, politician (Democrat), state representative 1979-2019
 - Betty Currie, personal secretary to President Bill Clinton
 - Adrianne Curry, model and America's Next Top Model winner
 - Eddy Curry, center for four NBA teams
 - Alan Curtis, actor, High Sierra, Buck Privates
 - Charlotte Curtis, journalist, New York Times
 - James Curtiss, Mayor of Chicago 1847–51 (born in Connecticut)
 - Mary Curzon, baroness
 - Ann Cusack, actress, The Jeff Foxworthy Show, Maggie
 - Joan Cusack, actress, Working Girl, In & Out, Broadcast News, School of Rock, Toy Story 2, Shameless
 - John Cusack, actor, Eight Men Out, Con Air, High Fidelity, The Grifters, Grosse Pointe Blank, 1408, 2012
 - Matt Cushing, NFL tight end 1999–2004
 - Clive Cussler, best-selling novelist, Raise the Titanic!, Sahara, creator of Dirk Pitt
 - Ethan Cutkosky, actor, Shameless
 - Slade Cutter, decorated World War II submarine officer
 - Mike Cvengros, MLB pitcher 1922–29
 - Ziggy Czarobski, Hall of Fame tackle for Notre Dame
 
D
Da–Dd
- Bob Dahl, NFL lineman 1991–97
 - Bill Daily, actor, I Dream of Jeannie, The Bob Newhart Show (born in Iowa)
 - Jon Daker. viral video star, known for a video of him singing in an unusual manner on public access tv in 1990.
 - John Francis Daley, actor, Bones, Freaks and Geeks
 - John P. Daley, Cook County commissioner
 - Richard J. Daley, politician (Democrat), member of Illinois State Assembly, Mayor of Chicago 1955–1976
 - Richard M. Daley, politician (Democrat), attorney, Illinois state senator, Mayor of Chicago 1989–2011, son of Richard J. Daley
 - William M. Daley, 1997-2000 U.S. Secretary of Commerce and 2011-12 White House Chief of Staff
 - Rick Dalpos, pro golfer
 - Dorothy Dalton, silent-film actress
 - Joel Daly, television journalist (born in Montana)
 - Lar Daly, perennial politician
 - Bill Damaschke, president of Warner Bros. animation
 - Mark Damon, producer and actor
 - Anthony D'Andrea, organized crime figure (born in Sicily)
 - Ben Daniels, lawman, one of Teddy Roosevelt's Rough Riders
 - Bert Daniels, MLB outfielder 1910–14
 - Owen Daniels, NFL tight end, played for Super Bowl 50 champion Denver Broncos
 - Randy Daniels, politician (Republican), Secretary of State of New York, Deputy Mayor of New York City
 - Shirley Danz, pro baseball player
 - Eleanor Dapkus, pro baseball player
 - Severn Darden, actor, charter member of Second City (born in Louisiana)
 - Scott Darling, NHL goaltender, played for 2015 Stanley Cup champion Chicago Blackhawks
 - Erik Darnell, NASCAR driver for Roush Fenway Racing
 - Lisa Darr, actress, Popular, Life As We Know It, Flesh 'n' Blood
 - Frankie Darro, actor
 - Clarence Darrow, renowned Chicago-based attorney, Leopold and Loeb case, Scopes Trial (born in Ohio)
 - Justin Whitlock Dart Sr., executive of Walgreens, Rexall
 - Tom Dart, sheriff of Cook County
 - Kristin Dattilo, actress, The Chris Isaak Show, Hitz
 - Brian Daubach, MLB outfielder, minor-league manager
 - Doris Davenport, actress, The Westerner
 - George Davenport, frontiersman, Rock Island settler, Davenport, Iowa named for him (born in England)
 - Bob Davidson, baseball umpire
 - Andrew Davis, film director, The Fugitive, Under Siege, A Perfect Murder, The Guardian
 - Anthony Davis, 2012 NCAA basketball champion with Kentucky, first pick of 2012 NBA draft, 2020 NBA champion with Los Angeles Lakers
 - Carl Davis, boxing cruiserweight champion, 2010
 - Carl Davis, music producer
 - Clifton Davis, actor and songwriter, "Never Can Say Goodbye"
 - Corey Davis, NFL wide receiver
 - Danny K. Davis, politician (Democrat), U.S. Representative
 - David Davis, campaign manager of Abe Lincoln, U.S. Senator, Supreme Court justice (born in Maryland)
 - Dorothy Salisbury Davis, crime novelist
 - Edith Luckett Davis, mother of Nancy Reagan (born in Virginia)
 - Floyd Davis, co-winner of 1941 Indianapolis 500
 - George Davis, magazine editor
 - George R. Davis, Civil War captain, U.S. Representative (born in Massachusetts)
 - Jessie Bartlett Davis, opera contralto
 - Miles Davis, jazz musician, bandleader and composer, Grammy Lifetime Achievement Award
 - Orbert Davis, trumpeter
 - Rece Davis, television sportscaster
 - Richard Davis, jazz musician
 - Scott Davis, defensive end for Los Angeles Raiders 1988–94
 - Shani Davis, two-time Olympic and world champion speed skater
 - Zachary Taylor Davis, architect, Comiskey Park, Archbishop Quigley Preparatory Seminary
 - Clinton Davisson, Nobel Prize-winning physicist who discovered electron diffraction
 - Charles G. Dawes, Vice President of United States 1925–29, winner of Nobel Peace Prize (born in Ohio)
 - Jimmy Dawkins, blues musician (born in Mississippi)
 - Johnny Dawson, golfer, course designer
 - William L. Dawson, politician (Democrat), U.S. Representative 1943–70 (born in Georgia)
 - J. Edward Day, lawyer and United States Postmaster General 1961–63
 - Todd Day, basketball player, all-time scoring leader for Arkansas
 
De–Dh
- Margia Dean, actress and Miss America 1939 runner-up
 - William F. Dean, World War II and Korean War general
 - Jeffery Deaver, mystery novelist
 - Billy DeBeck, cartoonist, creator of Barney Google
 - Eugene V. Debs, socialist, IWW union leader, presidential candidate (born in Indiana)
 - H. Joel Deckard, U.S. Representative for Indiana 1979–83
 - Steve Decker, MLB catcher 1990–99
 - Bill DeCorrevont, Northwestern and pro football player
 - Karen DeCrow, president of National Organization for Women
 - Frances Dee, actress, Wells Fargo, Four Faces West (born in California)
 - Lola Dee, singer
 - Merri Dee, television personality
 - John Deere, founder of Deere & Company (born in Vermont)
 - Archie Dees, two-time Big Ten basketball MVP (born in Mississippi)
 - Dudley DeGroot, coach of Washington Redskins and college teams
 - Jack DeJohnette, jazz drummer
 - Paul DeJong, MLB player (born in Florida)
 - Lois Delander, first Miss America from Illinois (1927)
 - Frederic Delano, railroad president, uncle of FDR (born in New York)
 - Lea DeLaria, actress, Orange Is the New Black
 - Vaughn De Leath, singer
 - Floyd Dell, novelist and playwright
 - The Dells, singing group, Rock and Roll Hall of Fame
 - Al Demaree, MLB pitcher 1912–19
 - AnnMaria De Mars, technology executive, author, world champion judoka; mother of Ronda Rousey
 - Bruce DeMars, four-star U.S. Navy admiral
 - William Dembski, mathematician, philosopher and theologian
 - Ray Demmitt, MLB outfielder 1909–19
 - Charles S. Deneen, two-term Governor of Illinois
 - Edward E. Denison, politician, U.S. Representative 1915–31
 - Elias Smith Dennis, politician, Civil War general (born in New York)
 - Richard Dent, Hall of Fame defensive lineman for Chicago Bears, MVP of Super Bowl XX (born in Georgia)
 - Thomas Dent, 19th Century attorney
 - Justin Dentmon, pro basketball player, 2010 top scorer in Israel Premier League
 - Grant DePorter, restaurateur
 - Oscar Stanton De Priest, U.S. Representative, civil rights advocate, first African American elected to Congress in 20th Century (born in Alabama)
 - Bruce Dern, Oscar-nominated actor, Black Sunday, The Great Gatsby, Silent Running, Family Plot, Coming Home, Nebraska
 - Ed Derwinski, politician, U.S. Representative 1959–83 and U.S. Secretary of Veteran Affairs 1989–92
 - Tony DeSantis, theater owner, Drury Lane
 - Jackie DeShannon, singer, "What the World Needs Now Is Love"
 - Paul Des Jardien, University of Chicago center, College Football Hall of Fame, MLB pitcher (born in Kansas)
 - Sam DeStefano, mobster
 - Reid Detmers, MLB pitcher, 2022 no-hitter for Los Angeles Angels
 - Armand Deutsch, film producer
 - William Emmett Dever, Mayor of Chicago 1923–27 (born in Massachusetts)
 - Richard A. Devine, lawyer, Cook County State's Attorney 1996-2008
 - Karla DeVito, singer and actress
 - Laura Devon, actress, Red Line 7000, Goodbye Charlie
 - Peter De Vries, author, Pete 'n' Tillie, Reuben, Reuben
 - James Dewar, baker, creator of Hostess Twinkie
 - John Dewey, philosopher (born in Vermont)
 - Lee DeWyze, singer, American Idol Season 9 winner
 - Susan Dey, actress, The Partridge Family, L.A. Law
 - Dennis DeYoung, musician for rock band Styx
 
Di–Dn
- Douglas Diamond, economist, 2022 Nobel Prize winner
 - David Díaz, lightweight boxing champion 2007–08
 - Victor Diaz, baseball player (born in Dominican Republic)
 - Andy Dick, comedian, NewsRadio (born in South Carolina)
 - Philip K. Dick, science-fiction author, stories became films Blade Runner, Minority Report, Total Recall
 - Augustus Dickens, brother of Charles Dickens (born in England)
 - Annamary Dickey, opera singer
 - Basil Dickey, screenwriter
 - Frances Dickinson, physician, clubwoman, writer
 - Johnny Dickshot, MLB outfielder 1936–45
 - Bo Diddley, rock and blues musician, composer, Rock and Roll Hall of Fame (born in Mississippi)
 - Nelson Diebel, swimmer, 1992 Olympic gold medalist
 - David Diehl, offensive tackle, two-time Super Bowl champion with New York Giants 2003–13
 - Pony Diehl, Wild West outlaw
 - Doug Dieken, offensive lineman for Cleveland Browns 1971–84
 - Ryan Diem, offensive tackle for Super Bowl XLI champion Indianapolis Colts 2001–11
 - Scott Dierking, running back for New York Jets 1977–83
 - William H. Dieterich, U.S. Senator of Illinois 1933–39
 - Charles Henry Dietrich, U.S. Senator and Governor of Nebraska
 - Vince DiFrancesca, football coach, Western Illinois, Iowa State
 - Tracy Dildy, basketball coach for Chicago State 2010-18
 - John Dillinger, notorious bank robber, lived and died in Chicago, subject of films Dillinger, Public Enemies (born in Indiana)
 - Frank Dillon, baseball player, Pacific Coast League Hall of Fame
 - Melinda Dillon, Oscar-nominated actress, A Christmas Story, Absence of Malice, Close Encounters of the Third Kind
 - Paul Dinello, actor, comedian, The Colbert Report
 - Gerald Di Pego, screenwriter, Sharky's Machine, Message in a Bottle
 - Everett Dirksen, politician (Republican), United States Senator 1951–69, Senate Minority Leader
 - Louis Disbrow, auto racer, drove in first four Indianapolis 500s
 - Roy O. Disney, co-founder of Walt Disney Productions
 - Walt Disney, iconic film and TV director, producer and animator, Disney studio founder and creator of Disneyland
 - Mike Ditka, Hall of Fame pro football player and coach, TV commentator (born in Pennsylvania)
 - Michael Diversey, brewer, 19th Century alderman (born in Germany)
 - Alan J. Dixon, politician (Democrat), state treasurer, U.S. Senator 1981–93
 - Jessy Dixon, gospel singer
 - Leo Dixon, MLB catcher 1925–29
 - Malik Dixon, basketball player, top scorer in 2005 Israel Premier League
 - Sherwood Dixon, lieutenant governor under Adlai Stevenson II
 - Willie Dixon, blues musician (born in Mississippi)
 
Do–Dt
- Conrad Dobler, NFL offensive lineman 1972–81
 - Larry Doby, baseball pioneer, outfielder, manager for Chicago White Sox (born in South Carolina)
 - Townsend F. Dodd, World War I pilot, Distinguished Service Medal
 - Katherine Sturges Dodge, illustrator
 - Dorothy L. Dodson, U.S. champion in javelin and shot put
 - John Doe, actor and musician with band X
 - Eddie Doherty, journalist, Oscar-nominated screenwriter
 - Edward A. Doisy, biochemist, 1943 Nobel Prize
 - Dave Dombrowski, MLB executive
 - Jim Donahue, 19th Century baseball player
 - John Donahoe, CEO of Nike, chairman of PayPal
 - Mark Donahue, lineman for Michigan and Cincinnati Bengals
 - Luke Donald, professional golfer, 1999 NCAA champion for Northwestern (born in England)
 - Dorothy Donegan, jazz pianist
 - Mike Donlin, baseball player and actor
 - George Donner, organizer of Donner Party (born in North Carolina)
 - Ral Donner, singer
 - Professor Mike Donovan, middleweight boxer of bare-knuckle era
 - Jimmy Dore, comedian, political commentator
 - Tom Dore, basketball player and broadcaster
 - Dolores Dorn, actress, The Bounty Hunter, Underworld U.S.A.
 - Thomas A. Dorsey, gospel musician
 - John Dos Passos, novelist
 - Ayo Dosunmu, basketball player for Illinois and Chicago Bulls
 - Emily Taft Douglas, politician, U.S. Representative, first female Democrat from state elected to Congress
 - Mike Douglas, singer and television talk-show host
 - Paul Douglas, professor, politician (Democrat), 18-year U.S. Senator of Illinois (born in Massachusetts)
 - Stephen A. Douglas, politician (Democrat), U.S. Senator 1847–61, presidential candidate vs. Abe Lincoln (born in Vermont)
 - John A. Dowie, faith healer, Zion, Illinois founder (born in Scotland)
 - Dave Downey, basketball player, holder of University of Illinois single-game scoring record
 - Jim Downey, writer, Saturday Night Live
 - Mike Downey, Los Angeles and Chicago newspaper columnist
 - Susan Downey, film producer, Sherlock Holmes, Iron Man 2, The Judge, wife of Robert Downey Jr.
 - Wayne A. Downing, four-star U.S. Army general
 - Kathleen Doyle, pro basketball player, 2020 Big Ten Player of the Year
 - Patti Solis Doyle, political consultant
 - Larry Doyle, infielder, New York Giants, 1912 National League MVP
 - Larry Doyle, writer, I Love You, Beth Cooper, The Simpsons
 - Betsy Drake, actress, wife of Cary Grant (born in France)
 - Francis M. Drake, Civil War general, Governor of Iowa
 - Frank Drake, astronomer, astrophysicist
 - John Drake, co-founder of Drake Hotel
 - Johnny Drake, NFL running back 1937–41
 - Tracy Drake, co-founder of Drake Hotel
 - Yochi Dreazen, journalist
 - Jack Drees, television sportscaster
 - Tom Dreesen, comedian
 - Lance Dreher, 1986 Mr. Universe
 - Theodore Dreiser, author, social activist (born in Indiana)
 - Chuck Dressen, football quarterback, baseball manager for Brooklyn Dodgers and four more MLB teams
 - Paddy Driscoll, Hall of Fame quarterback and head coach for Chicago Cardinals and Chicago Bears
 - Robert Drivas, actor, The Illustrated Man, Cool Hand Luke
 - Vincent Drucci, mobster
 - John Drury, television journalist
 - Charles Dryden, early 20th Century sportswriter
 
Du–Dz
- Fred Dubois, two-term U.S. Senator from Idaho
 - Richard L. Duchossois, horse racing executive
 - Kevin Duckworth, center for five NBA teams
 - Tammy Duckworth, veteran of Iraq War, U.S. Representative and U.S. Senator (born in Thailand)
 - Art Dufelmeier, played for 1947 Rose Bowl champion Illinois, coached Western Illinois 1960–68
 - John Duff, counterfeiter, Revolutionary War scout
 - Terrence A. Duffy, CEO of Chicago Mercantile Exchange
 - Dennis Dugan, director, actor, Big Daddy, Beverly Hills Ninja, Happy Gilmore, Jack and Jill, Grown Ups
 - Tom Duggan, television commentator
 - Tony Dumas, NBA player 1994–98
 - Sharon K.G. Dunbar, U.S. Air Force general
 - Arne Duncan, U.S. Secretary of Education 2009–15
 - Joseph Duncan, Governor of Illinois 1834–38, four-term U.S. Representative (born in Kentucky)
 - Michael Clarke Duncan, actor, The Green Mile, Kung Fu Panda, Armageddon, Planet of the Apes
 - Thomas Duncan, Civil War general
 - Katherine Dunham, dancer and choreographer
 - Russell E. Dunham, decorated World War II soldier
 - Robert Hugo Dunlap, officer at Iwo Jima, winner of Medal of Honor
 - Kevin Dunn, actor, Transformers, Nixon, Unstoppable, Veep
 - Nora Dunn, actress, comedian, Saturday Night Live, Sisters, Bruce Almighty, Three Kings
 - Edward Joseph Dunne, bishop of Dallas 1894–1910 (born in Ireland)
 - Finley Peter Dunne, author and journalist
 - Edward Fitzsimmons Dunne, Mayor of Chicago 1905–07 and Governor of Illinois 1913–17 (born in Connecticut)
 - George Dunne, president of Cook County Commissioners 1969–91
 - Murphy Dunne, actor, keyboard player for Blues Brothers
 - Santiago Durango, musician, attorney (born in Colombia)
 - Chad Durbin, pitcher for eight MLB teams
 - Dick Durbin, politician (Democrat), senior U.S. Senator of Illinois, Majority Whip, U.S. Representative
 - Jim Durkin, politician (Republican), state representative
 - Lindsey Durlacher, Greco-Roman wrestler, bronze medalist at World Championships
 - Charles Duryea, automotive pioneer
 - Jean Baptiste Point du Sable, settler, founder of Chicago
 - Erv Dusak, player for 1946 World Series champion St. Louis Cardinals
 - Charles Dvorak, pole vaulter, 1904 Olympic gold medalist
 - Christian Dvorak, NHL forward
 - Jim Dwyer, MLB outfielder, played for 1983 World Series champion Baltimore Orioles
 - Conor Dwyer, swimmer, gold medalist at 2012 London Olympics
 - Thomas Dyer, president of Chicago Board of Trade, Mayor of Chicago 1856–57 (born in Connecticut)
 - Walter Dyett, musician and educator
 - Jimmy Dykes, player and manager for White Sox (born in Pennsylvania)
 - Ryan Dzingel, pro hockey player
 
E
Ea–Em
- Amelia Earhart, pioneer aviator, Chicago Hyde Park High graduate (born in Kansas)
 - Glenn Earl, NFL safety 2004-09 (born in Michigan)
 - Mary Tracy Earle, writer
 - Jug Earp, pro football player
 - Wyatt Earp, iconic American West lawman, subject of Tombstone, My Darling Clementine, Gunfight at the O.K. Corral
 - Earth, Wind & Fire, band in Rock and Roll Hall of Fame
 - John Porter East, U.S. Senator for North Carolina 1981–86
 - Martin Eberhard, co-founder of Tesla Motors
 - Christine Ebersole, two-time Tony Award-winning actress and singer, Saturday Night Live, Ryan's Hope, 42nd Street
 - Roger Ebert, film critic, Pulitzer Prize-winning journalist, author, television personality, co-host of Siskel & Ebert
 - Buddy Ebsen, actor, The Beverly Hillbillies, Barnaby Jones, Captain January, Davy Crockett, Breakfast at Tiffany's
 - Vilma Ebsen, dancer and actress, Broadway Melody of 1936
 - Earl Eby, athlete, silver medalist in 1920 Summer Olympics
 - Garrett Eckbo, landscape architect
 - Walter Eckersall, fullback for Chicago 1905 national champions, Hall of Fame, sportswriter, referee
 - William Eckert, Major League Baseball commissioner 1965–68
 - James Eckhouse, actor, Beverly Hills, 90210
 - Nora Eddington, actress, wife of Errol Flynn
 - Dwight Eddleman, three-sport Illinois athlete, NBA All-Star
 - J. W. Eddy, politician, lawyer, Angels Flight designer (born in New York)
 - John R. Eden, 19th Century U.S. Representative (born in Kentucky)
 - Jim Edgar, secretary of state and 1991–99 Governor of Illinois
 - John Edgar, naval commander, land baron, politician (born in Ireland)
 - Robert W. Edgren, cartoonist, 1904 Olympic athlete
 - Benjamin S. Edwards, 19th Century lawyer and politician
 - Bruce Edwards, MLB catcher 1946–56
 - India Edwards, vice-chair of Democratic National Committee 1950–56
 - Jon Edwards, MLB pitcher 2014-19
 - Ninian Edwards, politician (Democratic-Republican), U.S. Senator 1818–26 and Governor of Illinois 1826–30 (born in Maryland)
 - Ninian Wirt Edwards, educator, married to sister of Mary Todd Lincoln
 - Steve Edwards, pro football lineman
 - Chandler Egan, NCAA, U.S. Amateur golf champion, course designer
 - Edward Egan, cardinal, archbishop of New York 2000–2009
 - Jennifer Egan, 2011 Pulitzer Prize-winning novelist
 - John Egan, guard for Loyola basketball 1963 national champions
 - John Joseph Egan, monsignor, civil rights activist
 - Walter Egan, golfer, 1904 Olympic gold medalist
 - Dave Eggers, writer, editor, and publisher, author of A Heartbreaking Work of Staggering Genius
 - Rube Ehrhardt, MLB pitcher 1924–29
 - Tim Ehrhardt, pole vaulter
 - David Eigenberg, actor, Steve Brady on Sex and the City
 - Deborah Eisenberg, short story writer, actress
 - Brett Eldredge, country singer
 - Charlie Elgar, bandleader (born in Louisiana)
 - Karl Eller, original owner of Phoenix Suns, CEO of Circle K
 - Kurt Elling, jazz singer
 - Bump Elliott, halfback for Michigan and Purdue, coach at Michigan, athletic director at Iowa, College Football Hall of Fame
 - Ezekiel Elliott, running back for Dallas Cowboys, 2015 Big Ten MVP, fourth pick of 2016 NFL Draft
 - Jake Elliott, kicker for Super Bowl LII champion Philadelphia Eagles
 - Pete Elliott, football head coach for Nebraska, Illinois, Cal and Miami, College Football Hall of Fame
 - Bo Ellis, basketball player for 1977 NCAA champion Marquette and Denver Nuggets
 - Fred Ellis, cartoonist
 - LaPhonso Ellis, center for four NBA teams
 - Nelsan Ellis, actor, True Blood, Get On Up
 - Larry Ellison, CEO of Oracle Corporation, philanthropist, owner of Indian Wells Tennis Garden (born in New York)
 - Daniel Ellsberg, activist who released Pentagon Papers
 - Elmer E. Ellsworth, first Civil War casualty (born in New York)
 - Bob Elson, Hall of Fame baseball broadcaster
 - John Ely, pitcher for Los Angeles Dodgers 2010–12
 - Melvin Ely, center-forward for five NBA teams
 - Ari Emanuel, Hollywood superagent, co-CEO of William Morris Endeavor
 - Rahm Emanuel, Mayor of Chicago 2011-19, U.S. Representative 2003–09, senior advisor to Bill Clinton 1993–98, Chief of Staff to Barack Obama 2009–10, U.S. Ambassador to Japan
 - Louis Lincoln Emmerson, merchant, secretary of state and Governor of Illinois 1929–33
 
En–Ez
- Eric Engberg, television journalist
 - Larry English, NFL linebacker 2009-15, two-time MAC MVP for Northern Illinois
 - Jason Enloe, pro golfer
 - Rex Enright, football coach, South Carolina 1938–56
 - William Enyart, politician (Democrat), U.S. Representative 2013–15
 - A. J. Epenesa, defensive lineman for Iowa and Buffalo Bills
 - Philip "Phil" Erenberg, gymnast, Olympic silver medalist
 - Paul Erickson, pitcher for Cubs 1941–48
 - Roger Erickson, MLB pitcher 1978–83
 - John Erlander, furniture manufacturer (born in Sweden)
 - John N. Erlenborn, politician (Republican), U.S. Representative 1965–85
 - Cameron Esposito, comedian
 - Joe Esposito, road manager of Elvis Presley, Michael Jackson
 - Joe Esposito, organized crime figure (born in Italy)
 - Sammy Esposito, infielder for White Sox 1952–63
 - Tony Esposito, 15-year goaltender for Chicago Blackhawks, member of Hockey Hall of Fame (born in Canada)
 - Bill Essick, MLB pitcher and scout
 - Richard Estes, photorealistic painter
 - Nick Etten, MLB first baseman 1938–47
 - Ruth Etting, singer, subject of Love Me or Leave Me (born in Nebraska)
 - Aja Evans, bobsledder, bronze medalist at 2014 Winter Olympics
 - Andrea Evans, actress, One Life to Live
 - Bergen Evans, television personality, professor (born in Ohio)
 - Bill Evans, jazz musician
 - Billy Evans, MLB umpire
 - Chick Evans, golfer, won U.S. Open as amateur, member of World Golf Hall of Fame
 - Dan Evans, baseball executive
 - Fred Evans, NFL defensive tackle 2006–13
 - John Evans, physician, governor of Colorado territory, co-founder of Northwestern University (born in Ohio)
 - Lane Evans, politician (Democrat), U.S. Representative 1983–2007
 - Marsha J. Evans, admiral, CEO of American Red Cross
 - Betty Everett, singer (born in Mississippi)
 - Elizabeth Hawley Everett, educator, writer
 - Phil Everly, singer with Everly Brothers, Rock and Roll Hall of Fame
 - Hoot Evers, MLB outfielder 1941–56 (born in Missouri)
 - Johnny Evers, Hall of Fame second baseman, managed Cubs and White Sox (born in New York)
 - Lisa Evers, radio-TV personality, former VP of Guardian Angels
 - Bryan Eversgerd, MLB pitcher and coach
 - Cory Everson, six-time Ms. Olympia (born in Wisconsin)
 - Jimmy Evert, tennis player and coach, father of Chris Evert
 - Eve Ewing, sociologist and writer, professor at University of Chicago
 - Fred Ewing, surgeon, Oklahoma football coach
 - Thomas W. Ewing, politician (Republican), U.S. Representative 1991–2001
 - William Lee D. Ewing, governor (14 days) and U.S. Senator 1835–37 (born in Kentucky)
 
F
Fa–Fh
- Red Faber, Hall of Fame pitcher for White Sox; three wins in 1917 World Series (born in Iowa)
 - Janet Fairbank, opera singer
 - N.K. Fairbank, soap manufacturer, philanthropist
 - Don Fairfield, pro golfer (born in Kansas)
 - Ben Falcone, actor, director, Tammy, The Boss
 - Rich Falk, basketball player and coach, Northwestern
 - Cy Falkenberg, MLB pitcher 1903–17
 - Richard Fancy, actor, General Hospital, The District, Seinfeld
 - Jim Fanning, MLB player, manager and general manager
 - Kay Fanning, newspaper editor and publisher
 - Dennis Farina, actor, Chicago police officer, Law & Order, Crime Story, Get Shorty, Manhunter, Saving Private Ryan
 - Chris Farley, comedian and actor, Second City and Saturday Night Live (born in Wisconsin)
 - Dot Farley, silent-film actress
 - Ed Farmer, pitcher for eight MLB teams, sportscaster
 - Mimsy Farmer, actress, Spencer's Mountain, Hot Rods to Hell
 - Henry Farnam, surveyor, builder and president of Chicago, Rock Island and Pacific Railroad (born in New York)
 - Elon J. Farnsworth, Union general in Civil War, killed at Gettysburg
 - John F. Farnsworth, Union general in Civil War, seven-term U.S. Representative (born in Canada)
 - Louis Farrakhan, Nation of Islam leader (born in New York)
 - James T. Farrell, author, Studs Lonigan
 - Charles B. Farwell, philanthropist, U.S. Senator (born in New York)
 - John V. Farwell, department store founder (born in New York)
 - Sal Fasano, MLB catcher 1996–2008
 - Jeff Fassero, pitcher for nine MLB teams
 - Nancy Faust, musician, stadium organist
 - Harris W. Fawell, politician (Republican), U.S. Representative 1985–99
 - Meagen Fay, actress, Second City, Dirty Rotten Scoundrels, Malcolm in the Middle
 - Kenneth Fearing, poet and novelist
 - Carol Feeney, rower, Olympic silver medalist
 - Jesse W. Fell, land baron, helped establish Illinois State University (born in Pennsylvania)
 - Alfred T. Fellheimer, architect
 - John Felske, MLB player and manager
 - Gary Fencik, defensive back for Super Bowl XX champion Chicago Bears
 - Jean Fenn, opera singer
 - Randy Fenoli, fashion designer, Say Yes to the Dress
 - Irene Fenwick, silent-film actress, wife of Lionel Barrymore
 - Tom Fergus, NHL center 1981–93
 - Helen Ferguson, film publicist and actress
 - Enrico Fermi, nuclear physicist, University of Chicago professor, 1936 Nobel Prize in Physics winner (born in Italy)
 - Joseph Ferriola, mobster
 - George Washington Gale Ferris Jr., inventor of Ferris wheel
 - Elisha P. Ferry, first Governor of Washington (born in Michigan)
 - Edwin Feulner, president of The Heritage Foundation 1977–2013
 - Tina Fey, actress and comedian, writer-performer for Second City (born in Pennsylvania)
 
Fi–Fn
- Lupe Fiasco, rapper, musician
 - Carl Fick, filmmaker, novelist
 - Orlando B. Ficklin, U.S. Representative 1843–49 (born in Kentucky)
 - Eugene Field, journalist and author
 - Marshall Field, businessman, department store founder and philanthropist (born in Massachusetts)
 - Marshall Field III, banker, publisher and philanthropist
 - Marshall Field IV, owner of Chicago Sun-Times 1956–65
 - Ted Field, entrepreneur, auto racing, film producer, Cocktail, Runaway Bride, Mr. Holland's Opus, Riddick
 - Jackie Fields, boxer, Olympic and pro welterweight champ
 - Joseph W. Fifer, Civil War officer, city attorney of Bloomington, Governor of Illinois (born in Virginia)
 - Tim Finchem, commissioner of golf's PGA Tour 1994-2016
 - Paul Findley, politician (Republican), U.S. Representative 1961–83
 - Vivian Fine, composer
 - Jim Finigan, MLB infielder 1954–59
 - Tom Fink, mayor of Anchorage, Alaska 1987–94
 - Jim Finks, pro football player and executive, Hall of Fame (born in Missouri)
 - Charles O. Finley, owner of Oakland A's 1960–81 (born in Alabama)
 - John Huston Finley, educator, New York Times editor
 - Michael Finley, pro basketball player, film producer
 - Katie Finneran, actress, two-time Tony Award winner
 - Allison Finney, golfer
 - Mauro Fiore, Oscar-winning cinematographer (born in Italy)
 - Harvey S. Firestone Jr., chairman of Firestone Tire and Rubber Company
 - Bill Fischer, lineman for NFL's Chicago Cardinals, member of College Football Hall of Fame
 - Bobby Fischer, world chess champion
 - Leo Fischer, sports journalist, basketball executive
 - John Fischetti, 1969 Pulitzer Prize-winning cartoonist (born in New York)
 - Bud Fisher, cartoonist, Mutt and Jeff
 - Eileen Fisher, fashion designer (born in New York)
 - George M.C. Fisher, CEO of Eastman Kodak and Motorola
 - Steve Fisher, basketball coach, San Diego State and 1989 NCAA champion Michigan
 - Carlton Fisk, Hall of Fame catcher for Red Sox and White Sox (born in Vermont)
 - Jack Fisk, film director, Oscar-nominated art and production designer, husband of Sissy Spacek
 - Horatio Fitch, silver medalist in 400 meters at 1924 Summer Olympics
 - John Fitzgerald, two-time Olympian in pentathlon
 - Pat Fitzgerald, football coach for Northwestern
 - Patrick Fitzgerald, U.S. Attorney, 2001–12 (born in New York)
 - Peter Fitzgerald, politician (Republican), U.S. Senator 1999–2005
 - Thomas R. Fitzgerald, judge, Supreme Court of Illinois 2000-10
 - John Fitzpatrick, catcher, 1,787 hits in minor leagues
 - Bob Fitzsimmons, boxing heavyweight champion (born in England)
 - Five Stairsteps, singing group, "O-o-h Child"
 - Max Flack, outfielder, played in 1918 World Series
 - The Flamingos, singing group, "I Only Have Eyes for You"
 - Crista Flanagan, comedic actress, MADtv
 - Walter Flanigan, co-founder of National Football League
 - Michael Flatley, dancer and choreographer, Lord of the Dance
 - P. J. Fleck, football head coach, Minnesota
 - Coby Fleener, NFL tight end 2012-17
 - Darius Fleming, linebacker for Notre Dame and New England Patriots
 - Bill Flemming, sportscaster
 - Art Fletcher, MLB player, coach and manager
 - Darrin Fletcher, MLB catcher 1989–2002
 - Calista Flockhart, actress, Ally McBeal, wife of Harrison Ford
 - Milton S. Florsheim, founder of Florsheim shoe company
 - Paul Flory, Nobel Prize-winning chemist
 - Cliff Floyd, MLB outfielder for seven teams, 1997 World Series champion
 - Fahey Flynn, Chicago radio-TV journalist (born in Michigan)
 - John Flynn, director, screenwriter, Rolling Thunder, The Outfit, Out for Justice, Lock Up
 - Neil Flynn, actor, Scrubs, The Middle
 
Fo–Fp
- Dan Fogelberg, folk/rock musician and composer
 - Lee Fogolin, NHL player 1974–87
 - Pat Foley, hockey broadcaster
 - Thomas C. Foley, U.S. Ambassador to Ireland 2006–09
 - Tim Foley, 10-year defensive back for Miami Dolphins
 - Mike Foltynewicz, MLB pitcher
 - Art Folz, banned NFL player
 - Ralph Foody, actor, Home Alone, Code of Silence
 - Tom Foran, U.S. Attorney, chief prosecutor of Chicago Seven trial
 - Betty Ford, 1974–1977 First Lady of the United States, founder of Betty Ford Center
 - Dorothy Ayer Gardner Ford, mother of President Gerald Ford
 - Harrison Ford, Oscar-nominated actor, Indiana Jones films, original Star Wars trilogy, Blade Runner, Patriot Games, Air Force One, The Fugitive, 42
 - Judith Ford, 1969 Miss America
 - Percy Ford, auto racer, third in 1921 Indy 500
 - Ruth VanSickle Ford, painter, director of Chicago Academy of Fine Arts
 - Thomas Ford, eighth Governor of Illinois (born in Pennsylvania)
 - Carl Foreman, Oscar-winning screenwriter, High Noon, The Bridge on the River Kwai, The Guns of Navarone
 - James Forman, Civil Rights leader
 - Harry Forrester, basketball coach
 - Josephine Forsberg, improv coach, Second City, Players Workshop
 - Aldo Forte, NFL player and coach
 - Frank Foss, pole vaulter, 1920 Summer Olympics gold medalist
 - George Edmund Foss, U.S. Representative 1895–1913
 - Bob Fosse, Oscar and Tony-winning choreographer, director, Cabaret, Sweet Charity, Lenny, Chicago, All That Jazz
 - Ray Fosse, catcher for five Major League teams
 - Steve Fossett, commodities trader, aviator, adventurer (born in Tennessee)
 - Bill Foster, politician (Democrat), U.S. Representative
 - Gloria Foster, actress, The Matrix
 - Greg Foster, hurdler, 10-time national champion, three-time world champion, 1984 Olympic silver medalist
 - Kevin Foster, MLB pitcher 1993–2001
 - Martin D. Foster, surgeon, mayor of Olney, U.S. Representative
 - Rube Foster, manager of Chicago American Giants, member of Baseball Hall of Fame (born in Texas)
 - Scott Michael Foster, actor, Greek, Chasing Life, Crazy Ex-Girlfriend
 - Susanna Foster, actress, Phantom of the Opera
 - David Foulis, Chicago golf pro and innovator (born in Scotland)
 - James Foulis, 1896 U.S. Open golf champion (born in Scotland)
 - Albert Fowler, mayor of Rockford 1864–68 (born in Massachusetts)
 - Bertha Fowler, educator, preacher, deaconess
 - Richard Fowler, radio host, media personality, activist, Fox News contributor
 - Carol Fox, opera impresario
 - Nellie Fox, Hall of Fame infielder for White Sox (born in Pennsylvania)
 - Terry Fox, MLB pitcher
 - Virgil Fox, organist
 - Kim Foxx, politician, Cook County State's Attorney
 - Redd Foxx, comedian and actor, Sanford and Son, Cotton Comes to Harlem, Harlem Nights (born in Missouri)
 - Bryan Foy, film producer
 
Fr–Fz
- Clint Frank, football player for Yale, winner of 1937 Heisman Trophy
 - Melvin Frank, director and screenwriter, White Christmas, A Funny Thing Happened on the Way to the Forum
 - Pat Frank, journalist and author
 - Art Frantz, umpire, crew chief of 1975 World Series
 - Frank Frantz, final Governor of Oklahoma Territory
 - Dennis Franz, Emmy-winning actor, NYPD Blue, Hill Street Blues, Dressed to Kill, American Buffalo, Die Hard 2
 - John E. Franz, organic chemist, discovered glyphosate
 - Jonathan Franzen, author, 2001 National Book Award winner
 - Chick Fraser, pitcher for 1907, 1908 champion Chicago Cubs
 - Laura Gardin Fraser, sculptor, coin designer
 - Bobby Frasor, basketball player, 2009 NCAA champion North Carolina
 - Jason Frasor, MLB relief pitcher 2004-15
 - Harry Frazee, owned Boston Red Sox, traded Babe Ruth
 - Walt Frazier, Hall of Fame guard for Southern Illinois and New York Knicks (born in Georgia)
 - Andy Frederick, offensive lineman for two Super Bowl champions
 - John T. Frederick, literary scholar, professor (born in Iowa)
 - Bud Freeman, big-band saxophonist
 - Cassidy Freeman, actress, musician, Smallville, Longmire
 - Charles E. Freeman, judge, Supreme Court of Illinois 1990-2018 (born in Virginia)
 - Donnie Freeman, pro basketball player
 - Kathleen Freeman, actress, The Blues Brothers, The Nutty Professor, North to Alaska, Blues Brothers 2000
 - Marvin Freeman, MLB pitcher 1986–96
 - Russ Freeman, jazz pianist
 - Von Freeman, saxophonist
 - Paul Frees, voice actor
 - Ashley Freiberg, auto racer
 - Augustus C. French, lawyer, Governor of Illinois 1846–53 (born in New Hampshire)
 - William M. R. French, first director of Art Institute of Chicago (born in New Hampshire)
 - Arny Freytag, photographer
 - Betty Friedan, writer, activist, feminist, author of The Feminine Mystique
 - William Friedkin, Oscar-winning director, The Exorcist, The French Connection, Sorcerer, To Live and Die in L.A.
 - Kinky Friedman, musician, novelist, Texas politician
 - Leo Friedman, songwriter, "Let Me Call You Sweetheart"
 - Milton Friedman, Nobel Prize-winning economist
 - Friend & Lover, singing duo, "Reach out of the Darkness"
 - Owen Friend, MLB infielder 1949–56
 - Johnny Frigo, violinist, bassist and songwriter
 - Art Fromme, MLB pitcher 1906–15
 - Charles Sumner Frost, architect of Navy Pier Auditorium, LaSalle Street Station (born in Maine)
 - Jim Fuchs, two-time Olympic medalist, 1951 Pan Am Games shot put and discus champion
 - Nicholas J. Fuentes, paleoconservative political commentator, podcaster, activist
 - Francis Fukuyama, philosopher, political economist, author
 - Charles Eugene Fuller, U.S. Representative 1903–13, 1915–26
 - Jack Fuller, editor and publisher of Chicago Tribune
 - Loie Fuller, pioneer of modern dance
 - Melville Fuller, lawyer, editor, politician, Chief Justice of United States 1888–1910 (born in Maine)
 - R. Buckminster Fuller, scientist, architect, inventor, author
 - Hugh Fullerton, early 20th Century sportswriter, exposed Black Sox scandal
 - Xavier Fulton, tackle in Canadian Football League
 - Zach Fulton, NFL offensive lineman 2014-21 (born in Michigan)
 - Ivan Fuqua, relay gold medalist, 1932 Summer Olympics
 - George Furth, playwright, actor, Butch Cassidy and the Sundance Kid, Shampoo, Cannonball Run
 - Jules Furthman, Oscar-nominated screenwriter, Mutiny on the Bounty, To Have and Have Not, Rio Bravo
 
G
Ga–Gd
- Marianne Gaba, actress, Miss Illinois USA 1957, Playboy Playmate
 - Andrew Gabel, speed skater, 1994 Olympic silver medalist
 - John Wayne Gacy, serial killer
 - Gadabout Gaddis, fly-fishing expert
 - Eddie Gaedel, baseball pinch-hitter
 - Belva Gaertner, inspiration for "Velma Kelly" in play and film Chicago
 - Gary Gaetti, MLB third baseman 1981-2000, won 1987 World Series with Minnesota Twins
 - Jim Gaffigan, comedian and actor
 - Ben Gage, announcer, husband of Esther Williams
 - Lyman J. Gage, politician (Republican), banker and US Secretary of The Treasury (born in New York)
 - Frank Galati, screenwriter and playwright
 - Milt Galatzer, MLB outfielder 1933–39
 - George Washington Gale, namesake of Galesburg, founder of Knox College (born in New York)
 - Gladys Gale, singer and actress
 - Johnny Galecki, actor, Roseanne, The Big Bang Theory
 - Harry Gallatin, forward for New York Knicks, player and coach for Southern Illinois, basketball Hall of Fame
 - Mary Onahan Gallery, writer, editor
 - Tom Gallery, actor, married to ZaSu Pitts
 - Ralph Galloway, pro football player
 - Paul Galvin, founder of Motorola
 - Harry Gamage, football coach, South Dakota, Kentucky
 - Lu Gambino, football player, MVP of 1948 Gator Bowl
 - Kevin Gamble, player for four NBA teams
 - Mason Gamble, actor, Dennis the Menace, Spy Hard, Rushmore
 - James Gammon, actor, Nash Bridges, Revenge, Major League
 - Gale Gand, chef, television personality
 - Mike Gandy, NFL lineman 2001–09
 - Jeanne Gang, architect
 - Terry Gannon, sportscaster for NBC, Golf Channel, basketball player for 1983 NCAA champion NC State
 - Rudolph Ganz, pianist, music educator (born in Switzerland)
 - Aimee Garcia, actress, Dexter, Greetings from Tucson, George Lopez
 - Dave Garcia, MLB manager
 - Barry Gardner, NFL player 1999–2006
 - Earle Gardner, MLB player 1908–1912
 - Robert Gardner, golfer, two-time U.S. Amateur champion
 - Wix Garner, football coach, Western Illinois 1942–47
 - Merrick Garland, attorney, judge, United States Attorney General
 - Jeff Garlin, actor, comedian, director, Curb Your Enthusiasm, Daddy Day Care, The Goldbergs
 - Rita Garman, judge, Supreme Court of Illinois 2001-22
 - Lee Garmes, Oscar-winning cinematographer
 - Kevin Garnett, NBA center 1995-2016, 2000 Olympic gold medalist, 2004 MVP of NBA, Hall of Fame (born in South Carolina)
 - Jimmy Garoppolo, quarterback, Eastern Illinois, New England Patriots, San Francisco 49ers
 - Scott Garrelts, pitcher for San Francisco Giants 1982-91
 - Darell Garretson, NBA referee in Hall of Fame
 - Augustus Garrett, land speculator, Mayor of Chicago 1843–46 (born in New York)
 - Dick Garrett, guard for four NBA teams
 - Harriet E. Garrison, physician; medical writer
 - Dave Garroway, Chicago radio-TV personality, first host of NBC's Today show (born in New York)
 - Jennie Garth, actress, Beverly Hills, 90210
 - Elbert Henry Gary, lawyer, county judge, corporate officer, a U.S. Steel founder; Gary, Indiana named for him
 - John Warne Gates, barbed wire mogul, founder of company that became Texaco
 - William Gates, subject of documentary Hoop Dreams
 - Bryan Gaul, pro soccer player
 - Janina Gavankar, actress, True Blood, The Mysteries of Laura
 - Hobart R. Gay, World War II general
 - Mitzi Gaynor, entertainer and actress, South Pacific, There's No Business Like Show Business, The Joker Is Wild, Golden Girl, Les Girls
 
Ge–Gm
- Jason Gedrick, actor, Iron Eagle, Boomtown, Murder One, Luck
 - Eric Gehrig, pro soccer player
 - Gary Geiger, outfielder for four MLB teams
 - Bill Geist, author, TV correspondent, CBS Sunday Morning
 - Willie Geist, co-host of MSNBC's Morning Joe and NBC's Today
 - Larry Gelbart, Emmy-winning television and Oscar-nominated film writer, Tony-winning playwright
 - Michael Gelman, television producer
 - Angelo Genna, organized crime figure (born in Sicily)
 - Bill George, 13-year linebacker for Chicago Bears, member of Pro Football Hall of Fame (born in Pennsylvania)
 - Francis George, Roman Catholic cardinal, Archbishop of Chicago
 - Kenny George, among tallest basketball players in history
 - Phil Georgeff, horse-racing caller of more than 95,000 races
 - Sid Gepford, NFL player
 - Henry Gerber, gay rights activist (born in Germany)
 - Neva Gerber, early 20th Century actress
 - Jami Gertz, actress, Still Standing, Sibs, Twister, Less than Zero
 - Jody Gerut, MLB outfielder 2003–10
 - Charlie Getzien, 19th Century MLB pitcher
 - Tavi Gevinson, blogger and feminist
 - Georgie Anne Geyer, journalist and author
 - Andrea M. Ghez, astrophysicist, 2020 Nobel Prize in Physics (born in New York)
 - Ray Giacoletti, basketball coach for Utah, Eastern Washington, Drake
 - Carl Giammarese, lead vocalist of The Buckinghams
 - Sam Giancana, organized crime figure
 - Mark Giangreco, Chicago sportscaster (born in New York)
 - John Giannini, basketball coach for Maine, La Salle
 - Alexi Giannoulias, state treasurer 2007-11, Illinois Secretary of State
 - Jim Gibbons, tight end for Detroit Lions 1958–68
 - Marla Gibbs, actress, The Jeffersons, 227, The Hughleys
 - Charles Gibson, television journalist and personality, ABC News and Good Morning, America
 - Diana Gibson, actress, Adventure's End, Behind the Headlines
 - Norwood Gibson, MLB pitcher 1903–06
 - Oliver Gibson, NFL defensive tackle 1995-2003
 - Emily Giffin, novelist
 - Barry Gifford, novelist, Wild at Heart
 - Florence Gilbert, silent-film actress
 - Warren Giles, National League president 1957–69, Hall of Fame
 - Zach Gilford, actor, Friday Night Lights
 - Kendall Gill, pro basketball player, commentator
 - Earl Gillespie, sportscaster
 - King C. Gillette, inventor of safety razor (born in Wisconsin)
 - Fred Gillies, tackle for Chicago Cardinals
 - Paul Gilmartin, comedian, podcaster, TV personality, Dinner and a Movie
 - Douglas H. Ginsburg, judge
 - Joe Girardi, MLB catcher 1989-2003, manager, four World Series championships with New York Yankees
 - Adele Givens, actress, The Hughleys, Queens of Comedy
 - Henry P. Glass, architect, Art Institute professor
 - Stephen Glass, journalist for The New Republic fired for fraud
 - Kid Gleason, player, manager for Chicago White Sox 1912-23 (born in New Jersey)
 - Roy Gleason, outfielder, 1-for-1 in only MLB at-bat
 - Otis F. Glenn, lawyer, U.S. Senator 1928–33
 - Caroline Glick, journalist, deputy managing editor of Jerusalem Post
 - Joseph Glidden, patented barbed wire (born in New York)
 - Gina Glocksen, two-time American Idol contestant
 - Al Glossop, MLB infielder 1939–46
 - Bruce Glover, actor, Diamonds Are Forever, Chinatown
 
Go–Gq
- Bob Goalby, professional golfer, winner of 1968 Masters Tournament
 - George Gobel, comedian, musician and Emmy Award-winning actor
 - Godfrey, comedian, actor
 - Timothy Goebel, figure skater, 2002 Olympics bronze medalist
 - John D. Goeken, founder of MCI Inc and Airfone
 - Billy Goelz, pro wrestler
 - Harold Goettler, World War I aviator
 - Mike Goff, NFL guard 1998–2009
 - Gracie Gold, U.S. champion figure skater (born in Massachusetts)
 - Albert Goldbarth, poet
 - Arthur Goldberg, U.S. Secretary of Labor 1961–62, Ambassador to U.N. 1965–68
 - Barry Goldberg, keyboardist, record producer
 - Bertrand Goldberg, architect, designer of Marina City
 - Sarah Goldberg, actress, 7th Heaven
 - Grant Golden, tennis player
 - Jack Golden, NFL linebacker 2000–03
 - James Goldman, playwright and screenwriter, The Lion in Winter, Nicholas and Alexandra, Robin and Marian
 - Ronald Goldman, murder victim in O. J. Simpson trial
 - William Goldman, author, Oscar-winning screenwriter, Butch Cassidy and the Sundance Kid, All the President's Men, The Princess Bride
 - Arlene Golonka, actress, Mayberry R.F.D., Hang 'Em High, The Busy Body
 - Andrew Golota, heavyweight boxer, 1988 Summer Olympics medalist (born in Poland)
 - Jaslene Gonzalez, fashion model, winner of America's Next Top Model Cycle 8
 - Benny Goodman, musician and bandleader, recipient of Grammy Lifetime Achievement Award
 - Steve Goodman, singer-songwriter, "City of New Orleans"
 - William O. Goodman, lumber tycoon, founder of Goodman Theater (born in Pennsylvania)
 - Charles Goodnight, cattle baron and trailblazer
 - Andrew Goodpaster, U.S. Army general, NATO Supreme Commander, superintendent of West Point
 - Ron Gora, swimmer, NCAA and Pan-Am Games champion
 - Alicia Goranson, actress, Roseanne, Boys Don't Cry, The Conners
 - Sarah Gorden, pro soccer player
 - Seth Gordon, director, Horrible Bosses, Identity Thief
 - Stuart Gordon, director, writer, producer, Re-Animator
 - Edward Gorey, artist and writer
 - Ken Gorgal, defensive back, 1950, 1954 NFL champion
 - Mark Gorski, cyclist, gold medalist in 1984 Summer Olympics
 - Tom Gorzelanny, pitcher for five MLB teams
 - Freeman Gosden, co-creator and star of Amos 'n' Andy
 - Tuffy Gosewisch, catcher for Arizona Diamondbacks
 - Jeff Gossett, NFL punter 1981–96
 - Sue Gossick, diver, gold medalist in 1968 Summer Olympics
 - Mark Gottfried, basketball coach, Alabama, NC State, Cal State Northridge (born in Ohio)
 - Robert Gottschalk, cameraman, founder of Panavision
 - Chester Gould, creator of Dick Tracy (born in Oklahoma)
 
Gra–Grd
- Harry Grabiner, longtime White Sox executive
 - Jim Grabowski, MVP of 1964 Rose Bowl, running back for Chicago Bears and Green Bay Packers, broadcaster
 - Joe Grace, MLB outfielder 1938–47
 - Thomas Joseph Grady, archbishop of Orlando, Florida 1974-89
 - Joseph V. Graff, lawyer, U.S. Representative 1895–1911 (born in Indiana)
 - Billy Graham, evangelist (born in North Carolina)
 - Bruce Graham, architect of Sears Tower and John Hancock Center (born in Colombia)
 - Kent Graham, NFL quarterback 1992–2002
 - Otto Graham, Hall of Fame quarterback for Cleveland Browns, head coach for Washington Redskins
 - Nancy Lee Grahn, actress, General Hospital, Santa Barbara
 - Peaches Graham, early 20th Century ballplayer
 - Stedman Graham, businessman, partner of Oprah Winfrey
 - Judy Grahn, poet
 - Billy Grammer, musician, "Detroit City"
 - Curtis Granderson, MLB outfielder 2004-19, three-time All-Star
 - Red Grange, college and pro Hall of Fame football player (born in Pennsylvania)
 - Bill Granger, novelist and journalist (born in Wisconsin)
 - Bob Grant, radio personality
 - Frederick Dent Grant, soldier, diplomat, son of President Ulysses S. Grant
 - James Grant, first president of Chicago and Rock Island Railroad
 - James Edward Grant, screenwriter, The Alamo, Hondo, McLintock!
 - Mark Grant, MLB pitcher 1984–93, broadcaster
 - Michael Grant, boxer
 - Ulysses S. Grant, commander of Illinois regiment, Civil War general and 18th President of the United States (1869–1877) (born in Ohio)
 - Ulysses S. Grant III, soldier, city planner, grandson of U.S. Grant
 - Cammi Granato, captain of 1998 Winter Olympics gold-medal U.S. women's hockey team, Hockey Hall of Fame
 - Tony Granato, player for three NHL teams, head coach of Colorado Avalanche 2002–04
 - Bonita Granville, film actress and TV producer, Nancy Drew franchise, The Glass Key, Now, Voyager
 - Laura Granville, professional tennis player
 - Nick Gravenites, blues musician
 - Catt Gravitt, songwriter
 - Beatrice Gray, actress
 - Charles McNeill Gray, candle maker, Mayor of Chicago 1853–54 (born in New York)
 - Clifford Gray, two-time gold medalist in 1932 Winter Olympics bobsled
 - Dolores Gray, actress, Designing Woman, It's Always Fair Weather, Kismet, The Opposite Sex
 - Glen Gray, bandleader and musician
 - Harold Gray, creator of Little Orphan Annie
 - Kenneth J. Gray, Air Force combat pilot, U.S. Representative 1955–89
 - William S. Gray, co-created Dick and Jane stories
 - Eli Grba, MLB pitcher 1959–63
 
Gre–Grz
- Andrew Greeley, Catholic priest, sociologist, columnist and author
 - Chad Green, pitcher for New York Yankees (born in South Carolina)
 - Dwight H. Green, 1941–49 Governor of Illinois, prosecutor of Al Capone (born in Indiana)
 - Rickey Green, guard for eight NBA teams
 - Shawn Green, MLB two-time All Star outfielder 1993–2007, had four-homer game
 - Gus Greenbaum, Chicago gangster, ran Flamingo Las Vegas
 - Seymour Greenberg, four-time US Open tennis quarterfinalist
 - Robert Greenblatt, chairman of NBC television entertainment
 - Dan Greenburg, author, husband of Nora Ephron
 - Gene Greene, ragtime musician
 - Kevin Greene, Hall of Fame linebacker for five NFL teams
 - Shecky Greene, comedian and actor, Tony Rome, History of the World, Part I, Splash
 - Ralph Greenleaf, pocket billiards Hall of Fame
 - Sam Greenlee, novelist, government agent
 - Luke Gregerson, MLB pitcher 2009-19, member of 2017 World Series champion Houston Astros
 - Virginia Gregg, actress
 - Rose Gregorio, Tony Award-nominated actress
 - Brian Gregory, basketball head coach, Georgia Tech, Dayton, South Florida
 - John Milton Gregory, first president of University of Illinois (born in New York)
 - Wilton Daniel Gregory, archbishop of Washington
 - Lori Greiner, TV personality, Shark Tank
 - Matt Grevers, two-time relay gold medalist in 2008 Olympic Games, backstroke gold in 2012 Olympics
 - Elmer Grey, architect of The Beverly Hills Hotel
 - Tom Gries, director, Will Penny, 100 Rifles, Breakheart Pass
 - Kenneth C. Griffin, financier, philanthropist (born in Florida)
 - Johnny Griffin, bop sax musician
 - Kathy Griffin, actress, Emmy-winning comedian, My Life on the D-List, Fashion Police
 - Marion Mahony Griffin, pioneering architect
 - Montell Griffin, boxer, WBC light-heavyweight champ
 - Walter Burley Griffin, architect, associated with Frank Lloyd Wright
 - Charles B. Griffith, screenwriter, The Little Shop of Horrors, Death Race 2000, Eat My Dust!
 - Clark Griffith, baseball player, manager, owner in Hall of Fame (born in Missouri)
 - Howard Griffith, NFL running back 1991–2001, eight-TD game for Illinois
 - John L. Griffith, first commissioner of Big Ten Conference
 - Rashard Griffith, pro basketball player
 - Yolanda Griffith, 2000 and 2004 Olympic basketball gold medalist, eight-time WNBA All-Star, 1999 league MVP
 - Boomer Grigsby, NFL fullback 2005–09
 - Dennis Grimaldi, Broadway choreographer, producer
 - Charlie Grimm, player and manager for Cubs (born in Missouri)
 - Gary Groh, golfer
 - Bob Groom, MLB pitcher 1909–18
 - Mary Gross, actress, Saturday Night Live, Feds, The Couch Trip, Troop Beverly Hills
 - Michael Gross, actor, Family Ties, Big Business, The Young and the Restless, Tremors
 - Johnny Groth, MLB outfielder 1946–60
 - Orval Grove, pitcher for White Sox 1940–49 (born in Kansas)
 - Sophie Naylor Grubb, activist, writer, lecturer
 - Johnny Gruelle, cartoonist, creator of Raggedy Ann
 - Dov Grumet-Morris, professional ice hockey player
 - Tim Grunhard, NFL center 1990–2000
 - John M. Grunsfeld, astronaut and physicist
 - Glen Grunwald, general manager of NBA's New York Knicks, Toronto Raptors
 
Gs–Gz
- Lisa Guerrero, model and television personality
 - Ozzie Guillén, infielder, manager for White Sox (born in Venezuela)
 - Charles J. Guiteau, assassin of President James A. Garfield
 - John Guleserian, cinematographer
 - Bill Gullickson, MLB pitcher 1979–94 (born in Minnesota)
 - Bryant Gumbel, television journalist (born in Louisiana)
 - Greg Gumbel, television sportscaster (born in Louisiana)
 - Frank W. Gunsaulus, educator, orator and minister (born in Ohio)
 - Charles F. Gunther, confectioner, introduced CrackerJack (born in Germany)
 - John Gunther, foreign correspondent and author
 - Larry Gura, pitcher for Kansas City Royals and Chicago Cubs
 - Walter S. Gurnee, tannery owner, Mayor of Chicago 1851–53; Gurnee named for him (born in New York)
 - Andy Gustafson, football coach, Virginia Tech, Miami
 - Frankie Gustine, MLB infielder 1939–50
 - Luke Guthrie, golfer
 - Luis Gutiérrez, politician (Democrat), U.S. Representative 1993-2019
 - Buddy Guy, blues guitarist, Grammy Lifetime Achievement Award
 - A.J. Guyton, basketball player
 - Boone Guyton, test pilot, aviation pioneer
 - Brad Guzan, pro soccer goalkeeper
 
H
Haa–Ham
- Bert Haas, MLB first baseman 1937–51
 - Carl Haas, auto racing executive (born in Germany)
 - Jay Haas, pro golfer, nine-time PGA Tour winner (born in Missouri)
 - Jerry Haas, pro golfer, college coach
 - Stan Hack, player and manager for Chicago Cubs (born in California)
 - Warren Hacker, MLB pitcher 1948–61
 - Gene Hackman, Oscar-winning actor, The French Connection, Superman, Hoosiers, Unforgiven (born in California)
 - H. G. Hadden, 1895 football player-coach for Notre Dame
 - Jerry Hadley, operatic tenor
 - Mickey Haefner, MLB pitcher 1943–50
 - Jean Hagen, Oscar-nominated actress, Singin' in the Rain, Adam's Rib, The Asphalt Jungle, Make Room for Daddy
 - Kevin Hagen, actor, Little House on the Prairie
 - Hager Twins, country music duo
 - Michael G. Hagerty, actor, Lucky Louie, Friends
 - Tyjuan Hagler, NFL player
 - Kathryn Hahn, actress, Crossing Jordan, Step Brothers, We're the Millers, Glass Onion, WandaVision
 - Rick Hahn, general manager of Chicago White Sox
 - John Charles Haines, water commissioner, Mayor of Chicago 1858–60 (born in New York)
 - Jerry Hairston Jr., baseball player for nine MLB teams
 - George Halas, co-founder of National Football League, coach-owner of Chicago Bears, member of Pro Football Hall of Fame
 - George Halas Jr., president of Chicago Bears 1963–79
 - Walter Halas, basketball coach, Notre Dame, Drexel
 - Barbara Hale, Emmy-winning actress, Della Street on Perry Mason
 - DeMarlo Hale, MLB bench coach
 - George E. Hale, astronomer
 - Arthur R. Hall, football player and coach for Illinois
 - Bryan Hall, pro football player 2011-17
 - Buddy Hall, pocket billiards Hall of Fame
 - Edward K. Hall, football and baseball coach for Illinois
 - Glenn Hall, 10-year Hall of Fame goalie for Blackhawks (born in Canada)
 - Lani Hall, singer, wife of Herb Alpert
 - Gary Hallberg, pro golfer, sixth in 1985 Masters
 - Bill Haller, Major League Baseball umpire
 - Tom Haller, MLB catcher, coach, executive
 - Brett Halliday, mystery writer
 - Lin Halliday, saxophonist (born in Arkansas)
 - Robert Halperin, Olympic yachting medalist, football player, World War II hero, chairman of Commercial Light Co.
 - Victor Halperin, film director, White Zombie
 - Halston, fashion designer (born in Iowa)
 - Roy Hamey, general manager of New York Yankees 1960–63
 - Dorothy Hamill, figure skater, gold medalist in 1976 Winter Olympics and 1976 world champion
 - Earl Hamilton, MLB pitcher 1911–24
 - Frank Hamilton, singer with The Weavers
 - John B. Hamilton, U.S. Surgeon General 1879–91
 - John Marshall Hamilton, Governor of Illinois 1883–85 (born in Ohio)
 - Todd Hamilton, pro golfer, winner of 2004 British Open
 - Penny Hammel, pro golfer, winner of 1983 NCAA championship
 - Richard Hamming, prominent mathematician, inventor of Hamming code and Hamming window
 - John Hammond, general manager of Orlando Magic, Milwaukee Bucks
 - Laurens Hammond, inventor of Hammond organ
 - Dan Hampton, Hall of Fame defensive end for Chicago Bears (born in Arkansas)
 
Han–Har
- Herbie Hancock, jazz musician, Grammy and Oscar winner
 - Elliot Handler, co-founder of Mattel toy company
 - Phil Handler, NFL player and coach
 - Jam Handy, Olympic swimmer (born in Pennsylvania)
 - Daryl Hannah, actress, Splash, Blade Runner, Wall Street, Steel Magnolias, Kill Bill
 - Page Hannah, philanthropist and actress, Shag, Fame
 - Lorraine Hansberry, playwright, A Raisin in the Sun
 - Henry C. Hansbrough, U.S. Senator of North Dakota 1891–1909
 - Brian Hansen, speed skater, 2010 Winter Olympics silver medalist
 - Chris Hansen, television journalist
 - Joseph T. Hansen, labor leader
 - Myrna Hansen, 1953 Miss USA, actress
 - Mark Victor Hansen, co-creator of Chicken Soup for the Soul
 - Snipe Hansen, MLB pitcher 1930–35
 - Ray Hanson, football coach, Western Illinois 1926–41 (born in Minnesota)
 - Robert Hanssen, FBI agent convicted of espionage
 - Norman Hapgood, editor, ambassador to Denmark 1919
 - J. A. Happ, MLB relief pitcher 2007-21
 - Luke Harangody, pro basketball player, 2008 Big East Player of the Year
 - Clay Harbor, NFL tight end 2010-17
 - James Harbord, World War I general, chairman of RCA
 - Tim Hardaway, NBA player 1989–2003 and 2000 Sydney Olympics gold medalist
 - Abner C. Harding, Civil War officer, U.S. Representative (born in Connecticut)
 - Cory Hardrict, actor, American Sniper, The Outpost
 - Phil Hare, U.S. Representative 2007-11
 - Alan Hargesheimer, MLB pitcher 1980–86
 - Cory Harkey, NFL tight end 2012-16
 - James Harlan, Iowa senator, U.S. Secretary of the Interior, son-in-law of Abraham Lincoln
 - John Marshall Harlan II, justice of U.S. Supreme Court 1955–71
 - Chic Harley, running back, College Football Hall of Fame
 - Jean Harlow, actress, Lake Forest student (born in Missouri)
 - Deborah Harmon, actress, Just the Ten of Us, Used Cars
 - Merle Harmon, sports broadcaster
 - Reginald C. Harmon, Air Force general
 - Ann Harnett, pro baseball player
 - Elise Harney, pro baseball player
 - Sheldon Harnick, lyricist, Fiddler on the Roof
 - Erika Harold, model, 2003 Miss America, conservative activist, attorney
 - Dawn Harper, hurdler, gold medalist in 2008 Beijing Olympics
 - Jesse Harper, football coach for Notre Dame 1913–17
 - Jessica Harper, actress, My Favorite Year, Stardust Memories, Pennies from Heaven, Suspiria
 - Michael Harper, basketball player, North Park and Portland Trail Blazers
 - William Rainey Harper, first president of University of Chicago and Bradley (born in Ohio)
 - Ken Harrelson, baseball player, executive, broadcaster (born in South Carolina)
 - Will Harridge, president of baseball's American League 1931–59
 - Arne Harris, television sports producer
 - Barbara Harris, Oscar-nominated actress, Nashville, Plaza Suite, Family Plot, Freaky Friday
 - E.B. Harris, 25-year president of Chicago Mercantile Exchange
 - Eddie Harris, saxophonist
 - Emily Harris, kidnapper of Patty Hearst
 - Harry Harris, boxer
 - Janet Harris, member of Women's Basketball Hall of Fame
 - Moira Harris, actress, One More Saturday Night, Breakdown, wife of Gary Sinise
 - Napoleon Harris, linebacker in NFL, member of Illinois Senate
 - Patricia Roberts Harris, Cabinet member of President Jimmy Carter
 - Paul P. Harris, founder of Rotary International (born in Wisconsin)
 - Robin Harris, comedian and actor, House Party, Do the Right Thing
 - Steve Harris, actor, The Practice, Diary of a Mad Black Woman
 - Sydney J. Harris, syndicated columnist (born in England)
 - Wood Harris, actor, The Wire, Ant-Man, Creed films
 - Carter Harrison Sr., politician (Democrat), U.S. Representative, Mayor of Chicago 1879–1887, 1893 (born in Kentucky)
 - Carter Harrison Jr., politician (Democrat), Mayor of Chicago 1897–1905, 1911–15
 - Nolan Harrison, NFL defensive end 1991–2000
 - Rodney Harrison, NFL defensive back, won two Super Bowls with New England Patriots
 - Dolores Hart, actress, Loving You, Lonelyhearts, Sail a Crooked Ship, Where the Boys Are
 - Jim Hart, quarterback for NFL's St. Louis Cardinals 1966–83
 - Pearl M. Hart, attorney and activist
 - Justin Hartley, actor, Passions, The Young and the Restless, Smallville
 - Mary Hartline, television personality, Super Circus
 - Johnny Hartman, jazz singer (born in Louisiana)
 - Gabby Hartnett, Hall of Fame catcher for Chicago Cubs (born in Rhode Island)
 - Lynne Cooper Harvey, radio producer (born in Missouri)
 - Paul Harvey, radio personality, Chicago-based for more than 60 years (born in Oklahoma)
 
Has–Haz
- Karen Hasara, politician (Republican), first female mayor of Springfield
 - Dennis Hastert, teacher, politician (Republican), U.S. Representative, Speaker of the House 1998–2006, imprisoned 2016
 - Wilbur Hatch, bandleader, I Love Lucy
 - Donny Hathaway, singer, "Where Is the Love"
 - Helge Alexander Haugan, businessman, banker (born in Norway)
 - H. (Hauman) G. Haugan, railroad executive, brother of Helge A. Haugan (born in Norway)
 - Reidar Rye Haugan, newspaper publisher (born in Norway)
 - Enid A. Haupt, magazine publisher, philanthropist
 - Herbert Hans Haupt, executed spy (born in Germany)
 - June Haver, actress, The Daughter of Rosie O'Grady, The Dolly Sisters, Look for the Silver Lining, wife of Fred MacMurray
 - Brent Hawkins, pro football player 2006–13
 - Coleman Hawkins, saxophonist (born in Missouri)
 - Fred Hawkins, golfer, co-runnerup in 1958 Masters
 - Hersey Hawkins, guard for five NBA teams
 - LaRoyce Hawkins, actor, Chicago P.D.
 - Tom Hawkins, basketball player, baseball executive
 - John Hay, secretary to Abe Lincoln, U.S. Secretary of State under William McKinley and Theodore Roosevelt (born in Indiana)
 - Kelvin Hayden, NFL cornerback 2005–14, won Super Bowl XLI
 - Julie Haydon, actress, The Scoundrel, The Conquerors
 - Bernadene Hayes, actress, Idiot's Delight, Dick Tracy's Dilemma
 - Bill Hayes, actor, Days of Our Lives
 - Billie Hayes, actress, Li'l Abner
 - Charles Hayes, union official, U.S. Representative 1983–93
 - Reggie Hayes, actor, Girlfriends
 - Sean Hayes, Emmy-winning actor, Will & Grace, The Bucket List, Martin and Lewis, The Three Stooges
 - Kathryn Hays, actress, As the World Turns
 - Reggie Hayward, NFL defensive end 2001-09
 - Hurley Haywood, auto racer in Motorsports Hall of Fame of America
 
He–Hh
- Luther Head, basketball player, 2005 Illinois national runners-up
 - Nathan Heald, commandant of Fort Dearborn 1810–12 (born in New Hampshire)
 - Egyptian Healy, 19th Century pitcher
 - George Peter Alexander Healy, painter (born in Massachusetts)
 - Pat Healy, actor, Station 19, Draft Day
 - Jane Heap, writer and publisher (born in Kansas)
 - Chick Hearn, Hall of Fame basketball broadcaster for Los Angeles Lakers
 - Monroe Heath, politician (Republican), Mayor of Chicago 1876–79 (born in New Hampshire)
 - Erin Heatherton, fashion model
 - Harry Hebner, three-time Olympian, 1912 backstroke gold medalist
 - Ben Hecht, reporter, war correspondent, activist, playwright, director, Oscar-winning screenwriter
 - Bobby "The Brain" Heenan, professional wrestler, manager, TV commentator
 - Kyle T. Heffner, actor, Flashdance, When Harry Met Sally..., Runaway Train
 - Richard T. Heffron, director, I, the Jury, Futureworld, Outlaw Blues
 - Christie Hefner, former Playboy company CEO
 - Hugh Hefner, magazine publisher, founder of Playboy
 - James V. Heidinger, U.S. Representative 1941–45
 - Mike Heimerdinger, assistant coach for Denver Broncos and Tennessee Titans
 - Don Heinrich, NFL quarterback 1953–62 and coach, College Football Hall of Fame
 - Ryan Held, swimmer, 2016 Summer Olympics gold medalist
 - Marg Helgenberger, actress, Northwestern alumna, CSI (born in Nebraska)
 - William Heirens, convicted murderer, served 65 years in prison
 - James Meredith Helm, admiral, Spanish–American War
 - Ernest Hemingway, iconic author, Pulitzer and Nobel Prize-winning journalist and novelist
 - Grace Hall Hemingway, opera singer, mother of Ernest Hemingway
 - Terri Hemmert, Chicago radio personality (born in Ohio)
 - Bill Henderson, jazz singer, actor, Clue, City Slickers
 - Rickey Henderson, Hall of Fame outfielder, holds MLB record for career stolen bases
 - Thomas J. Henderson, Civil War general, U.S. Representative (born in Tennessee)
 - Jack Hendricks, manager of Cincinnati Reds 1924–29
 - Sue Hendrickson, paleontologist, discoverer of Sue the dinosaur
 - Tim Hendryx, MLB outfielder 1911–21
 - Max Henius, biochemist, co-founder of American Academy of Brewing
 - Marilu Henner, actress, author, Taxi, Evening Shade, Noises Off, Johnny Dangerously, L.A. Story
 - Anne Henning, speed skater, 1992 Olympic gold medalist (born in North Carolina)
 - John W. Henry, businessman and investor, owner of Boston Red Sox and The Boston Globe
 - Ken Henry, speed skater, gold medalist in 1952 Winter Olympics
 - Roy Henshaw, MLB pitcher 1933–44
 - Kelley Menighan Hensley, actress, As the World Turns
 - Lou Henson, 21-year head coach of Illinois basketball (born in Oklahoma)
 - Craig Hentrich, NFL punter 1993–2009
 - Herblock (Herbert Block), cartoonist, winner of three Pulitzer Prizes
 - William Herndon, law partner and biographer of Abe Lincoln, mayor of Springfield
 - James B. Herrick, physician who discovered sickle-cell disease
 - Clarence Herschberger, All-American athlete for University of Chicago 1894–98
 - Seymour Hersh, Pulitzer-winning investigative journalist
 - John D. Hertz, founder of Yellow Cab Company and The Hertz Corporation (born in Hungary)
 - Whitey Herzog, outfielder, Hall of Fame baseball manager, primarily with St. Louis Cardinals
 - Charlton Heston, Oscar-winning actor, political activist, The Ten Commandments, Ben-Hur, El Cid, The Greatest Show on Earth, The Agony and the Ecstasy, Touch of Evil, Planet of the Apes
 - Willie Heston, halfback, College Football Hall of Fame
 
Hi–Hn
- John Grier Hibben, president of Princeton University 1912–32
 - Jesse Hibbs, football player for USC, film and TV director
 - Jim Hickey, MLB pitching coach
 - Kevin Hickey, pitcher for White Sox and Baltimore Orioles
 - Fred Hickman, sportscaster
 - Wild Bill Hickok, Wild West gunfighter and lawman, depicted in The Plainsman, Calamity Jane, Wild Bill
 - Ronald Aldon Hicks, bishop of Joliet
 - Hal Higdon, runner and writer
 - Joan Higginbotham, astronaut
 - Jarad Higgins, hip-hop musician and songwriter
 - Jack Higgins, cartoonist, 1989 Pulitzer Prize winner
 - Joel Higgins, actor, Silver Spoons
 - Rod Higgins, forward for seven NBA tams, executive for Charlotte Hornets
 - Andy High, MLB third baseman 1922–34
 - Nat Hiken, creator, Car 54, Where Are You?, The Phil Silvers Show
 - Ernest Hilgard, psychologist
 - Nick Hill, football head coach, Southern Illinois
 - Virginia Hill, moll to Chicago Outfit mob (born in Alabama)
 - Homer Hillebrand, MLB player 1905–08
 - Chuck Hiller, MLB player, hit grand slam home run in 1962 World Series
 - Charles T. Hinde, founder of Hotel del Coronado (born in Ohio)
 - Harry Hinde, Missouri politician, aircraft designer
 - Thomas S. Hinde, founder of Mount Carmel, friend of Mark Twain
 - Earl Hines, jazz musician (born in Pennsylvania)
 - Garrett Hines, bobsled silver medalist at 2002 Salt Lake City Olympics
 - Tony Hinkle, basketball coach (born in Indiana)
 - Chris Hinton, tackle for Indianapolis Colts and Atlanta Falcons
 - Milt Hinton, jazz musician (born in Mississippi)
 - Edward Hirsch, poet and critic
 - Lew Hitch, won two NBA championships with Minneapolis Lakers
 - Michael Hitchcock, actor, MADtv, Wild Hogs, Glee (born in Ohio)
 - Les Hite, bandleader
 - Robert R. Hitt, U.S. Representative 1882–1906 (born in Ohio)
 
Ho–Ht
- Edward Francis Hoban, archbishop of Cleveland, Ohio 1945–66
 - Glen Hobbie, pitcher for Chicago Cubs 1957–64
 - Mellody Hobson, executive, chairperson of DreamWorks Animation, married to George Lucas
 - Nathan Hodel, NFL center 2001–09
 - Art Hodes, jazz pianist (born in Ukraine)
 - John R. Hodge, commanding general of U.S. Third Army
 - Craig Hodges, NBA guard, primarily with Milwaukee Bucks and Chicago Bulls
 - Reggie Hodges, NFL punter 2005–12
 - Tom Hoff, volleyball player, gold medalist in 2008 Beijing Olympics
 - Guy Hoffman, pitcher in MLB and Japan
 - Julius Hoffman, judge in trial of Chicago Seven
 - Isabella Hofmann, actress, Dear John, Homicide: Life on the Street, JAG
 - Paul G. Hoffman, auto executive and statesman
 - James F. Hoge Jr., editor and publisher of Chicago Sun-Times, New York Daily News
 - Helen E. Hokinson, cartoonist for The New Yorker
 - William Holabird, architect (born in New York)
 - Stu Holcomb, GM of White Sox and Chicago Mustangs soccer, Northwestern athletic director
 - Charles C. P. Holden, 19th Century politician (born in New Hampshire)
 - Jennifer Holden, actress, Buchanan Rides Alone, Jailhouse Rock
 - William Holden, Oscar-winning actor, Stalag 17, Sunset Boulevard, Born Yesterday, The Bridge on the River Kwai, Picnic, The Wild Bunch, Network
 - John Holecek, NFL linebacker 1995-2002, coach at Loyola Academy
 - Tony Holguin, golfer
 - Nicole Hollander, creator of comic strip Sylvia
 - Mabel Holle, baseball player
 - Robert W. Holley, biochemist, 1968 Nobel Prize
 - Loleatta Holloway, singer
 - Red Holloway, jazz musician
 - Celeste Holm, Oscar-winning actress, Gentleman's Agreement, All About Eve (born in New York)
 - Andre Holmes, NFL wide receiver 2011-18
 - H. H. Holmes, serial killer (born in New Hampshire)
 - Mary Emma Holmes, reformer, suffragist, and educator
 - Phyllis Holmes, basketball coach, Women's Basketball Hall of Fame
 - Richaun Holmes, NBA forward
 - Nick Holonyak, engineer and educator
 - Lester Holt, Chicago newscaster 1986–2000, NBC News anchor (born in California)
 - Redd Holt, jazz drummer
 - Stefan Holt, Chicago newscaster, son of Lester Holt
 - Jerome Holtzman, baseball writer and historian
 - Ken Holtzman, pitcher for University of Illinois, Cubs, Oakland A's, three-time World Series winner
 - Joseph R. Holzapple, U.S. Air Force four-star general
 - Dianne Holum, speed skater, Olympic gold medalist
 - James Holzhauer, TV game show champion, Jeopardy!
 - Skip Homeier, actor, The Gunfighter, The Tall T, Comanche Station
 - Gene Honda, announcer
 - John Honnold, professor at University of Pennsylvania Law School
 - Hector Honore, auto racer (born in Kansas)
 - Henry Honore, 19th Century real estate baron (born in Kentucky)
 - Ida Marie Honore, socialite, daughter-in-law of Ulysses S. Grant (born in Kentucky)
 - Raymond Hood, architect of Tribune Tower and Rockefeller Center (born in Rhode Island)
 - Jay Hook, MLB pitcher 1957–64
 - Michael Hoomanawanui, NFL tight end 2010-18, member of Super Bowl XLIX champion New England Patriots
 - Albert J. Hopkins, U.S. Representative 1885–1903, U.S. Senator 1903–09
 - Brad Hopkins, NFL offensive tackle 1993-2005 (born in South Carolina)
 - Fred Hopkins, jazz musician
 - John Patrick Hopkins, politician (Democrat), Mayor of Chicago 1893–95 (born in New York)
 - Michael S. Hopkins, astronaut, Illinois football player (born in Missouri)
 - Jeff Hornacek, NBA player 1986–2000, head coach of New York Knicks, Phoenix Suns
 - Henry Horner, politician (Democrat), Governor of Illinois 1933–40
 - Rogers Hornsby, Hall of Fame infielder, manager for Chicago Cubs (born in Texas)
 - Big Walter Horton, harmonica player in Blues Hall of Fame
 - Kathleen Horvath, pro tennis player
 - Arnold Horween, All-American for Harvard, NFL player
 - Ralph Horween, All-American for Harvard, NFL player
 - Frances Horwich, television personality, Miss Frances, host of Ding Dong School
 - Tanner Houck, MLB pitcher
 - Stanley Hough, horse racing trainer
 - Lin Houston, guard for 1950 NFL champion Cleveland Browns
 - Charles Edward Hovey, Civil War general, Peoria school superintendent, first president of Illinois State (born in Vermont)
 - Richard Hovey, poet
 - Del Howard, won 1907 and 1908 World Series with Chicago Cubs
 - Juwan Howard, forward for Michigan and eight NBA teams; two championships with Miami Heat, head coach at Michigan
 - Margaret Howard, countess
 - Margo Howard, writer, daughter of Ann Landers (born in Iowa)
 - Miki Howard, singer
 - Terrence Howard, Oscar-nominated actor, Hustle & Flow, Iron Man, Crash, Big Momma's House, The Butler, Empire
 - Tom Howard, photographer
 - Dick Howell, swimmer, 1924 Summer Olympics relay gold medalist
 - George Evan Howell, judge, U.S. Representative 1941–47
 - Yvonne Howell, actress, wife of director George Stevens
 - Howlin' Wolf, Chicago blues musician in Rock and Roll Hall of Fame (born in Mississippi)
 
Hu–Hz
- Elbert Hubbard, writer, died on RMS Lusitania
 - Trenidad Hubbard, MLB outfielder 1994–2003
 - Edwin Hubble, astronomer (born in Missouri)
 - Janet Hubert, singer, actress, Fresh Prince of Bel Air
 - Kelli Hubly, pro soccer player
 - Winnifred Mason Huck, first Illinois woman in Congress
 - Reginald Hudlin, film director, producer, The Great White Hype, Django Unchained
 - Warrington Hudlin, film director, producer, House Party, Boomerang
 - Jennifer Hudson, Grammy-winning R&B singer, Oscar-winning actress, Dreamgirls
 - Michael Hudson, economist
 - Otis Hudson, NFL lineman 2010–14
 - Rock Hudson, actor, Giant, Magnificent Obsession, Pillow Talk, A Farewell to Arms, Ice Station Zebra, McMillan and Wife
 - Troy Hudson, NBA guard 1998–2008
 - George Huff, 19th Century football and baseball coach for Illinois, athletic director 1901–35
 - Brandon Hughes, NFL cornerback 2009–14
 - Carol Hughes, actress, Flash Gordon Conquers the Universe
 - Jim Hughes, MLB pitcher 1952–57
 - John Hughes, director, producer, screenwriter, Ferris Bueller's Day Off, The Breakfast Club, Home Alone (born in Michigan)
 - John R. Hughes, cowboy, trail driver, Texas Ranger
 - Kim Hughes, pro basketball center and coach
 - Mary Beth Hughes, actress, The Ox-Bow Incident, Dressed to Kill, Caged Fury, Loophole, The Lady Confesses
 - Matt Hughes, mixed martial artist, UFC Hall of Fame
 - Pat Hughes, baseball broadcaster (born in Arizona)
 - Robert Hughes, NFL and Notre Dame fullback
 - Tom Hughes, MLB pitcher 1900–13
 - Wayne Huizenga, founder of Blockbuster video, owned Miami Dolphins, Florida Marlins
 - William Hulbert, baseball pioneer, president of Chicago White Stockings, who became the Cubs (born in New York)
 - Tim Hulett, MLB player and coach
 - Bobby Hull, Hall of Fame wing for Chicago Blackhawks (born in Canada)
 - Morton D. Hull, lawyer, U.S. Representative 1923–33
 - William E. Hull, postmaster of Peoria, U.S. Representative 1923–33
 - Randy Hultgren, U.S. Representative 2011-19
 - Edward Hume, TV writer, The Day After
 - Paul Hume, music critic
 - Rick Hummel, baseball writer
 - Todd Hundley, catcher for several MLB teams (born in Virginia)
 - Murray Humphreys, organized crime figure
 - William L. Hungate, U.S. Representative of Missouri 1964–77
 - Chuck Hunsinger, pro football player
 - Bonnie Hunt, actress, director, talk-show host, Beethoven, Jerry Maguire, Cheaper by the Dozen, Return to Me
 - Brendan Hunt, co-creator and cast member of Ted Lasso
 - H. L. Hunt, oil tycoon
 - Jarvis Hunt, architect
 - Lester C. Hunt, U.S. Senator and Governor of Wyoming
 - Marsha Hunt, actress, Raw Deal, Panama Hattie, Johnny Got His Gun, Carnegie Hall
 - Myron Hunt, architect of Rose Bowl stadium (born in Massachusetts)
 - Richard Hunt, sculptor
 - Stephen Hunter, novelist, Pulitzer Prize-winning critic (born in Missouri)
 - Steven Hunter, center for four NBA teams
 - Stephen A. Hurlbut, lawyer, Civil War general, ambassador (born in South Carolina)
 - John Huston, pro golfer, top-five in 1990 Masters, 2000 U.S. Open
 - Ken Huszagh, swimmer, 1912 Olympic Games gold medalist
 - Robert Maynard Hutchins, lawyer, president of University of Chicago (born in New York)
 - Ina Ray Hutton, entertainer and bandleader
 - June Hutton, singer and actress
 - J.B. Hutto, blues musician (born in South Carolina)
 - Dick Hyde, MLB pitcher 1955–61
 - Henry J. Hyde, politician (Republican), U.S. Representative 1975–2007, chaired House Judiciary Committee
 - Ida Henrietta Hyde, physiologist and professor (born in Iowa)
 - J. Allen Hynek, astronomer, UFO authority
 
I
- Harold L. Ickes, U.S. Secretary of the Interior under FDR and Truman (born in Pennsylvania)
 - Harold Iddings, college football, basketball coach
 - Andre Iguodala, four-time NBA champion player for Golden State Warriors, 2015 NBA Finals MVP
 - James Iha, musician with The Smashing Pumpkins
 - Tunch Ilkin, lineman, broadcaster for Pittsburgh Steelers
 - Margaret Illington, silent-film actress
 - Roger Imhof, actor
 - The Impressions, R&B group, Rock and Roll Hall of Fame
 - Ebon C. Ingersoll, U.S. Representative 1864–70 (born in New York)
 - Robert G. Ingersoll, 19th Century Illinois Attorney General, reformer (born in New York)
 - Lloyd Ingraham, actor and director
 - Mark Ingram Sr., NFL wide receiver 1987–96, father of Heisman Trophy winner Mark Ingram II
 - Rex Ingram, actor, The Adventures of Huckleberry Finn, Sahara, Cabin in the Sky, Your Cheatin' Heart
 - Jeff Innis, pitcher for New York Mets 1987–93
 - Samuel Insull, industrialist, builder of Chicago Opera House (born in England)
 - George Ireland, coach of Loyola team that won 1963 NCAA basketball championship (born in Wisconsin)
 - Jim Irsay, owner of NFL's Indianapolis Colts
 - Robert Irsay, owned Baltimore and Indianapolis Colts 1972–97
 - Dick Irvin, coach and first captain of Chicago Blackhawks (born in Canada)
 - Wilson Irvine, impressionist painter
 - Charlie Irwin, MLB infielder 1893–1902
 - Ivan Irwin, NHL player, New York Rangers, Montreal Canadiens
 - Tom Irwin, actor, Saving Grace, My So-Called Life, Related
 - Jason Isringhausen, relief pitcher for six MLB teams
 - Dan Issel, Hall of Fame basketball player, University of Kentucky, Denver Nuggets, NBA coach and GM
 - Burl Ives, Oscar-winning actor, The Big Country, Cat on a Hot Tin Roof; folk musician ("A Holly Jolly Christmas")
 - Judith Ivey, Tony Award-winning actress, Sister, Sister, Brighton Beach Memoirs, The Woman in Red (born in Texas)
 - Eugene Izzi, novelist working in hardboiled crime fiction
 
J
Ja–Jn
- Ray Jablonski, MLB infielder 1953–59
 - Adoree Jackson, USC and NFL wide receiver
 - Frisman Jackson, NFL wide receiver 2002–07
 - Jesse Jackson, political activist and candidate, Baptist minister, TV commentator (born in South Carolina)
 - Jesse Jackson Jr., U.S. Representative, tendered resignation 2012
 - Jonathan Jackson, U.S. Representative
 - Leroy Jackson, three-time state 100-yard dash champion, NFL running back
 - Mahalia Jackson, gospel singer, Grammy Lifetime Achievement Award (born in Louisiana)
 - Mannie Jackson, owner of Harlem Globetrotters
 - Mark Jackson, NFL wide receiver 1986-94, played in three Super Bowl games
 - Michael Jackson, iconic pop singer (born in Indiana)
 - Phil Jackson, Hall of Fame coach of six-time NBA champion Chicago Bulls (born in Montana)
 - Shoeless Joe Jackson, outfielder for Black Sox banned from baseball (born in South Carolina)
 - Wilfred Jackson, animator, director of Disney's Fantasia, Dumbo, Cinderella, Snow White and the Seven Dwarfs
 - Harry Jacobs, pro linebacker 1960–72, two AFL championships
 - Jim Jacobs, composer, Grease
 - Colombe Jacobsen, chef and actress
 - Baby Doll Jacobson, MLB outfielder 1915–27
 - Peter Jacobson, actor, House, Transformers, Ray Donovan
 - Walter Jacobson, television news journalist
 - Scott Jacoby, Emmy-winning actor
 - Andrea Jaeger, tennis player, Wimbledon and French Open finalist
 - Thomas Jaeschke, volleyball player, 2016 Olympic medalist
 - Evan Jager, distance runner, U.S. record holder in 3000m steeplechase
 - Tom Jager, swimmer, five-time Olympic champion, 11-time U.S. champion
 - Helmut Jahn, architect (born in Germany)
 - John Jakes, author, The Kent Family Chronicles, North and South
 - Ahmad Jamal, jazz pianist
 - Brian James, basketball coach
 - Edmund J. James, president of University of Illinois 1904–20
 - Joni James, singer, "Why Don't You Believe Me?"
 - Louis N. James, golfer, 1902 U.S. Amateur champion
 - Peter Francis James, actor, voice-over artist
 - William James, NFL defensive back 2001–10
 - Joyce Jameson, actress
 - Bob Jamieson, television journalist
 - Dick Jamieson, football coach 1972–97
 - Jim Jamieson, pro golfer (born in Michigan)
 - Bob Janecyk, NHL goalie 1983–89
 - Bill Janklow, 16-year Governor of South Dakota
 - Danny Jansen, MLB catcher
 - Natalie Jaresko, minister of finance, Ukraine
 - Joseph Jarman, jazz musician and Buddhist priest (born in Arkansas)
 - Valerie Jarrett, senior advisor to President Barack Obama
 - Pat Jarvis, pitcher for Montreal Expos and Atlanta Braves
 - Ray Jauch, football player and coach
 - Dick Jauron, NFL defensive back, head coach of Buffalo Bills, Chicago Bears and Detroit Lions
 - Dave Jauss, baseball coach and scout
 - William Jayne, first governor of Dakota Territory 1861–63
 - Betty Jaynes, singer and actress (born in Tennessee)
 - Robert Jeangerard, Olympic basketball gold medalist
 - Denise Jefferson, director Alvin Ailey American Dance Theater 1984–2010
 - Thomas B. Jeffery, 19th Century auto and bicycle pioneer (born in England)
 - Mae Jemison, physician and astronaut (born in Alabama)
 - Joe Jemsek, golfer and owner of Cog Hill course
 - Edward H. Jenison, publisher, Naval commander, U.S. Representative (born in Wisconsin)
 - Ella Jenkins, educator, Grammy-winning singer
 - Ferguson Jenkins, Hall of Fame pitcher for Chicago Cubs (born in Canada)
 - LaTasha Jenkins, sprinter
 - Leroy Jenkins, violinist
 - Richard Jenkins, Oscar-nominated, Emmy-winning actor, The Visitor, Six Feet Under, Step Brothers, Olive Kitteridge
 - James M. Jenness, CEO of Kellogg's 2004–06
 - William Le Baron Jenney, architect, originator of metal-frame skyscraper (born in Massachusetts)
 - William Sherman Jennings, 18th Governor of Florida
 - Derrick Jensen, tight end for Oakland Raiders 1979–86
 - Jens Jensen, landscape architect (born in Denmark)
 - Jeremih, R&B singer
 - Garry Jestadt, MLB infielder 1969–72
 - Rob Jeter, basketball coach, Milwaukee, Western Illinois (born in Pennsylvania)
 - Sam Jethroe, outfielder, 1950 National League Rookie of the Year
 - Martin C. Jischke, president of Iowa State and Purdue
 
Jo–Jz
- Anton J. Johnson, dairy executive, mayor of Macomb, U.S. Representative
 - Armon Johnson, point guard for Portland Trail Blazers 2010–12
 - Arnold Johnson, owner of MLB's Philadelphia and Kansas City Athletics
 - Arte Johnson, actor, Rowan & Martin's Laugh-In
 - Bob Johnson, pitcher for five Major League teams
 - Bobby Johnson, wide receiver for New York Giants 1984–86
 - Brandon Johnson, 57th Mayor of Chicago
 - Carrie Ashton Johnson, newspaper editor, writer, suffragist
 - Charles R. Johnson, scholar, novelist, author of Middle Passage
 - Chic Johnson, comedian, Olsen and Johnson
 - Curley Johnson, player for Harlem Globetrotters
 - Diane Johnson, author and screenwriter, Le Divorce, The Shining
 - Don Johnson, MLB player, last Cub to bat in World Series before 2016
 - Eddie Johnson, player for six NBA teams
 - Ernie Johnson, MLB shortstop 1912–25
 - George E. Johnson Sr., cosmetics executive (born in Mississippi)
 - Howard Wesley Johnson, president of MIT, chairman of board of trustees
 - Jake Johnson, actor, New Girl, Let's Be Cops, The Mummy
 - Jan Johnson, three-time NCAA pole vault champion, 1972 Olympic medalist
 - Jim Johnson, defensive coordinator for Notre Dame, NFL teams
 - John H. Johnson, publisher of Ebony, Jet (born in Arkansas)
 - Lynn-Holly Johnson, professional ice skater and actress, Ice Castles, For Your Eyes Only
 - Mickey Johnson, NBA forward 1974–86
 - Nancy Johnson, U.S. Representative for Connecticut 1983–2007
 - Phillip E. Johnson, professor, father of intelligent design movement
 - Raylee Johnson, NFL defensive end 1993–2003
 - Richard Johnson, defensive back for Houston Oilers
 - Robert L. Johnson, founder of Black Entertainment Television, owned Charlotte Bobcats (born in Mississippi)
 - Sheila Johnson, philanthropist, owner of Washington Mystics (born in Pennsylvania)
 - Syleena Johnson, singer and TV personality
 - Timothy V. Johnson, politician (Republican), U.S. Representative 2001–13
 - Luke Johnsos, player and coach for Chicago Bears
 - Bruce Johnston, singer for Beach Boys, composer of "I Write the Songs"
 - J. J. Johnston, actor, boxing historian
 - Louis Jolliet, explorer, early Illinois territory settler (born in Canada)
 - Adam Jones, Grammy-winning guitarist
 - Amanda Jones, 1973 Miss USA, first runner-up Miss Universe
 - Austin Jones, former YouTuber, musician, and a capella artist
 - Barbara Jones, sprinter, 1952 and 1960 Olympic relay golds
 - Darryl Jones, guitarist for The Rolling Stones
 - David Jones, physician, second owner of NFL's Chicago Cardinals
 - Earl Jones, athlete, 800 meters bronze in 1984 Summer Olympics
 - Esther Jones, sprinter, 1992 Summer Olympics relay gold
 - Garrett Jones, MLB first baseman and outfielder 2007-15
 - Hoppy Jones, original member of singing group The Ink Spots
 - James Jones, author, From Here to Eternity, Some Came Running, The Thin Red Line
 - Jo Jones, drummer for Count Basie
 - Mary Harris Jones, labor organizer (born in Ireland)
 - Melvin Jones, founder of Lions Club International (born in Arizona)
 - Ralph Jones, coach of Chicago Bears, basketball coach at Purdue, Illinois and Butler (born in Indiana)
 - Quincy Jones, musician, conductor, producer, arranger, composer, film composer, Grammy Legend Award
 - Rickie Lee Jones, Grammy-winning singer and songwriter
 - Sam J. Jones, actor, Flash Gordon, 10, Ted
 - Wesley Livsey Jones, U.S. Senator of Washington 1909–32
 - Bob Jordan, television journalist (born in Georgia)
 - Clifford Jordan, jazz musician
 - Jim Jordan, actor, radio's Fibber McGee and Molly
 - John Jordan, basketball coach for Loyola and Notre Dame
 - Marian Driscoll Jordan, actress, Fibber McGee and Molly
 - Michael Jordan, basketball player, NCAA champion, two-time Olympic champion, six-time NBA champion for Chicago Bulls, owner of Charlotte Hornets (born in North Carolina)
 - Reggie Jordan, NBA guard 1994–2000
 - Art Jorgens, MLB catcher 1929–39 (born in Norway)
 - Orville Jorgens, MLB pitcher 1935–37
 - Ron and Vivian Joseph, Olympic pairs skaters
 - Al Joyner, athlete, gold medalist in triple jump at 1984 Summer Olympics
 - Jackie Joyner-Kersee, athlete, UCLA basketball and track, four-time Olympian, three golds, six medals
 - Tom Joyner, radio personality
 - Norman B. Judd, U.S. Representative 1867–71 (born in New York)
 - Howie Judson, pitcher for Chicago White Sox, Cincinnati Reds
 - Sylvia Shaw Judson, sculptor
 - Whitcomb L. Judson, inventor of the zipper
 - Jakob Junis, MLB pitcher
 - John Jurkovic, football player, radio personality
 - Herb Juul, MLB pitcher, Illinois basketball player, coach
 
K
Ka–Kg
- Ted Kaczynski, notorious Unabomber criminal
 - Mike Kafka, NFL and Northwestern quarterback
 - Gus Kahn, songwriter, "I'll See You in My Dreams" (born in Germany)
 - James Kahn, writer of Star Wars novels, television producer
 - Harry Kalas, Hall of Fame sportscaster for Philadelphia Phillies
 - Floyd Kalber, longtime Chicago television journalist (born in Nebraska)
 - Frank Kaminsky, NBA center, 2015 Big Ten Player of the Year
 - Stuart M. Kaminsky, mystery novelist
 - Elias Kane, judge, first Illinois Secretary of State, U.S. Senator 1825–35 (born in New York)
 - Marjorie Kane, actress, The Dentist, The Loud Mouth
 - Patrick Kane, three-time Stanley Cup champion with Chicago Blackhawks (born in New York)
 - Maria Kanellis, WWE professional wrestler
 - Kraig Kann, Golf Channel personality, LPGA official
 - Henry Kaplan, pioneer in radiation therapy and radiobiology
 - Irving Kaplansky, mathematician at University of Chicago (born in Canada)
 - Jack Kapp, founder of Decca Records
 - Chris Kappler, Olympic equestrian gold medalist
 - Frederick J. Karch, World War II and Vietnam general
 - Fred Karger, political consultant
 - Fred Karlin, songwriter, "For All We Know"
 - Phil Karlson, film director, Kid Galahad, Kansas City Confidential, The Silencers, Walking Tall
 - Lloyd A. Karmeier, judge, Illinois Supreme Court 2000-20
 - Roberta Karmel, Centennial Professor at Brooklyn Law School, first female Commissioner of U.S. Securities and Exchange Commission
 - Johnny Karras, halfback for Illinois 1952 Rose Bowl champions
 - Ted Karras, NFL center, two-time Super Bowl champion with New England Patriots
 - Kevin Kasper, wide receiver for eight NFL teams
 - Leon Kass, physician, scientist, educator, public intellectual
 - Chuck Kassel, NFL player 1927–33
 - Terry Kath, musician with band Chicago
 - Stana Katic, actress, Castle, Absentia (born in Canada)
 - Philip Kaufman, film director, The Right Stuff, The Unbearable Lightness of Being, Rising Sun
 - Tony Kaufmann, MLB pitcher 1921–35
 - Herminie Templeton Kavanagh, writer, Darby O'Gill and the Little People (born in England)
 - Yosh Kawano, 65-year employee of Chicago Cubs (born in Washington)
 - Kenneth Kays, decorated soldier
 - Marilyn Kaytor, food writer
 - Tim Kazurinsky, actor, comedian, Saturday Night Live, Police Academy
 - Bill Keating, lineman, 1965 Rose Bowl champion Michigan
 - Tom Keating, NFL defensive tackle 1964–75
 - Julie Kedzie, mixed martial artist
 - Howard Keel, actor, singer, Seven Brides for Seven Brothers, Kiss Me Kate, Kismet, Calamity Jane, Dallas
 - James Keeley, newspaper publisher (born in England)
 - John L. Keeley Jr., investment manager and philanthropist
 - Leslie Keeley, physician, founder of Keeley Institute for addiction treatment
 - Cody Keenan, speechwriter for President Barack Obama
 - Rosalind Keith, actress, Criminals of the Air, Trouble in Sundown
 - Clayton Keller, NHL player (born in Missouri)
 - Kent E. Keller, U.S. Representative 1931–41
 - Sheldon Keller, comedy writer
 - Barry Kelley, actor, The Asphalt Jungle, Buchanan Rides Alone
 - Florence Kelley, social reformer, founder of National Consumers' League (born in Pennsylvania)
 - Mike Kelley, creator of TV series Revenge
 - Hiram Huntington Kellogg Sr., minister, first Knox College president (born in New York)
 - Dennis Kelly, NFL offensive tackle
 - Edward Joseph Kelly, 14-year Mayor of Chicago
 - Harry Kelly, decorated World War I soldier, Governor of Michigan
 - James Kelly, founder of Chicago Tribune
 - Megyn Kelly, journalist for Fox News and NBC News, host of Megyn Kelly Today
 - R. Kelly, singer and songwriter
 - Robin Kelly, politician (Democrat), U.S. Representative (born in New York)
 - Tim Kelly, NFL offensive coordinator
 - Caren Kemner, volleyball player, bronze medal in 1992 Summer Olympics
 - Mike Kenn, tackle for Atlanta Falcons, starter in 251 NFL games
 - Michael Kenna, saloonkeeper, Chicago alderman
 - Bob Kennedy, MLB player 1939-57, manager of Chicago Cubs and Oakland A's
 - Christopher G. Kennedy, president of Merchandise Mart, university trustee, nephew of John F. Kennedy (born in Massachusetts)
 - D. James Kennedy, pastor, Christian broadcaster
 - Ethel Kennedy, widow of U.S. senator and attorney general Robert F. Kennedy, awarded Presidential Medal of Freedom
 - John Kennedy, MLB infielder 1962–74
 - Madge Kennedy, actress, The Marrying Kind, Lust for Life
 - Merna Kennedy, actress, wife of Busby Berkeley
 - Martin H. Kennelly, Mayor of Chicago 1948–55
 - Ernie Kent, basketball head coach for Washington State and Oregon
 - Mel Kenyon, auto racer, five top-5 finishes in Indy 500
 - Robert Keohane, co-founder of neoliberalism school of thought
 - Hugh Keough, horse racing official and sportswriter
 - Joe E. Kernan, decorated Vietnam War aviator, mayor of South Bend 1988-97, Governor of Indiana 2003–05
 - Otto Kerner Jr., politician (Democrat), decorated World War II soldier, Governor of Illinois 1961–68, imprisoned 1974
 - Otto Kerner Sr., judge, Attorney General of Illinois
 - Johnny Kerr, NBA player, coach, broadcaster for Chicago Bulls, member of Hall of Fame
 - Walter Kerr, Broadway drama critic
 - Jack Kerris, Loyola and pro basketball player
 - Donald Kerst, physicist, worked on Manhattan Project
 - Brian Kerwin, actor, Murphy's Romance, Love Field, Torch Song Trilogy, 27 Dresses, Beggars and Choosers
 - Joseph Kerwin, astronaut and physician
 - T'Keyah Crystal Keymáh, actress, That's So Raven, Cosby, In Living Color
 - Madison Keys, tennis player, 2017 U.S. Open runner-up
 
Kh–Kn
- Chaka Khan, singer, multiple Grammy Award winner
 - Fazlur Khan, designer of John Hancock Center, Willis Tower (born in India)
 - Shahid Khan, owner, Jacksonville Jaguars (born in Pakistan)
 - Gerald Frederick Kicanas, archbishop of Tucson, Arizona
 - John Kidd, NFL punter 1984–98
 - Adolph Kiefer, swimmer, backstroke gold medalist in 1936 Olympics
 - Thomas L. Kilbride, judge, Supreme Court of Illinois 2000-20
 - Richard Kiley, Emmy and Tony Award-winning actor, Blackboard Jungle, A Year in the Life, Man of La Mancha, The Phenix City Story
 - Dorothy Kilgallen, columnist, game show panelist
 - Philip G. Killey, director of Air National Guard
 - James M. Kilts, CEO of Gillette
 - William Wallace Kimball, piano manufacturer (born in Maine)
 - Elbert Kimbrough, defensive back for San Francisco 49ers 1962–66
 - Kyle Kinane, stand-up comedian
 - Dave Kindred, sports journalist
 - Bill King, radio voice of Oakland A's, Raiders, Golden State Warriors
 - Bradley King, early Hollywood screenwriter
 - Edward John King, seven-term U.S. Representative (born in Massachusetts)
 - Frank King, cartoonist, creator of Gasoline Alley (born in Wisconsin)
 - Freddie King, musician in Blues Hall of Fame (born in Texas)
 - Ginevra King, socialite
 - Mary-Claire King, geneticist
 - Ray King, MLB pitcher 1999–2008
 - Wayne King, bandleader
 - Dave Kingman, 15-year MLB outfielder (born in Oregon)
 - Sam Kinison, stand-up comedian, actor (born in Washington)
 - Terry Kinney, actor, Oz, The Unusuals, Sleepers, The Firm, co-founder of Steppenwolf Theatre Company
 - William Kinney, lieutenant governor 1826–30 (born in Kentucky)
 - John Kinsella, swimmer, gold medalist at 1972 Summer Olympics
 - Juliet Magill Kinzie, historian (born in Connecticut)
 - John Kinzie, early Chicago settler (born in Ireland)
 - John H. Kinzie, trader, Chicago politician (born in Canada)
 - Adam Kinzinger, Air Force pilot, politician (Republican), U.S. Representative 2011-23
 - Jason Kipnis, MLB second baseman 2011-20
 - Bob Kipper, MLB pitcher 1985–92
 - George Kirby, comedian
 - Rollin Kirby, cartoonist
 - Mark Kirk, politician (Republican), U.S. Representative 2001-10 and U.S. Senator 2010-17
 - Jeane Kirkpatrick, U.S. Ambassador to United Nations 1981-85 (born in Oklahoma)
 - Jess Kirkpatrick, actor and announcer
 - Jimmy Kite, auto racer
 - Kurt Kittner, quarterback for Illinois, champion and MVP of World Bowl XIII
 - Tom Kivisto, basketball player, businessman
 - Nick Kladis, basketball player, businessman, part-owner of Chicago White Sox, St. Louis Cardinals
 - Billy Klaus, MLB player 1952-63
 - Bobby Klaus, MLB player 1964-65
 - Gary Kleck, criminologist, Florida State University professor emeritus
 - Chris Klein, actor, American Pie film series, Rollerball
 - Dick Klein, first owner, general manager of Chicago Bulls (born in Iowa)
 - Dick Klein, tackle for Chicago Bears, Dallas Cowboys
 - Tom Kleinschmidt, basketball player for DePaul, coach of DePaul College Prep
 - Josh Kline, NFL offensive guard 2013-19
 - William G. Kline, basketball and baseball coach, Nebraska and Florida
 - Frank Klopas, soccer player, coach of Chicago Fire
 - Karlie Kloss, fashion model
 - John C. Kluczynski, politician (Democrat), U.S. Representative 1951–75
 - Ted Kluszewski, first baseman for Cincinnati Reds, Chicago White Sox, three home runs in 1959 World Series
 - Philip Klutznick, U.S. Secretary of Commerce 1980–81, Chicago Bulls president 1973 (born in Missouri)
 - Cole Kmet, NFL tight end
 - Anthony L. Knapp, U.S. Representative 1861–65 (born in New York)
 - Lindsay Knapp, guard for Notre Dame and Super Bowl XXXI champion Green Bay Packers
 - Robert M. Knapp, U.S. Representative 1873–79 (born in New York)
 - Willie Knapp, jockey in Hall of Fame, winner of 1918 Kentucky Derby
 - Chad Knaus, NASCAR crew chief
 - Alexa Scimeca Knierim, figure skater, 2015 national pairs champion
 - Joe Knollenberg, U.S. Representative of Michigan 1993–2009
 - Oscar Knop, NFL halfback 1920–27
 - Frank Knox, newspaper publisher/owner and Secretary of the Navy (born in Massachusetts)
 
Ko–Kz
- Tom Koch, writer for Mad magazine
 - Leo Kocialkowski, tax appraiser, U.S. Representative 1933–43
 - Dave Kocourek, tight end in seven AFL title games
 - Dave Koechner, actor, Second City, Anchorman (born in Missouri)
 - Walter Koenig, actor, Star Trek
 - Gustav Koerner, lieutenant governor, Abe Lincoln aide (born in Germany)
 - Bob Koester, founder of Delmark Records (born in Kansas)
 - Seana Kofoed, actress, Men in Trees
 - Herman Kogan, journalist
 - Rick Kogan, journalist
 - Herbert Kohler Jr., billionaire businessman, CEO of Kohler Co.
 - Ruth DeYoung Kohler, journalist
 - H. H. Kohlsaat, newspaper publisher
 - Dick Kokos, MLB outfielder 1948–54
 - Dan Kolb, MLB pitcher 1999–2007
 - Gary Kolb, MLB outfielder 1960–69
 - Darlene Koldenhoven, Grammy Award-winning singer
 - Henry Kolker, actor, Holiday, Union Pacific
 - Fred Koller, songwriter
 - Don Kolloway, MLB infielder 1940–53
 - Bonnie Koloc, folk singer (born in Iowa)
 - Lou Kolls, football player, MLB umpire
 - Mort Kondracke, political commentator, columnist for Roll Call
 - Paul Konerko, 15-year first baseman for White Sox (born in Rhode Island)
 - Lee Konitz, saxophonist
 - George Kontos, relief pitcher for San Francisco Giants
 - David Kopay, pro football running back, author, gay rights activist
 - Harvey Korman, actor and comedian, The Carol Burnett Show, Blazing Saddles, History of the World, Part I, High Anxiety
 - Sidney Korshak, labor lawyer
 - Eddie Kotal, pro football player
 - Glenn Kotche, drummer
 - Arlene Kotil, pro baseball player
 - Irene Kotowicz, pro baseball player
 - George Kotsiopoulos, TV personality, Fashion Police
 - Rich Koz, television personality Svengoolie
 - Joe Krabbenhoft, basketball player, coach for Wisconsin
 - Joe Krakoski, NFL defensive back 1961–66
 - Irene Kral, singer
 - Roy Kral, jazz musician
 - Akiane Kramarik, poet and painter
 - Olof Krans, Civil War soldier in Illinois regiment, Swedish-American painter and artist
 - Nelson G. Kraschel, Governor of Iowa 1937–39
 - Jerry Krause, general manager of six-time NBA champion Chicago Bulls
 - Moose Krause, four-sport athlete, coach, athletic director for Notre Dame
 - Alison Krauss, multiple Grammy Award-winning bluegrass musician and composer
 - Mike Kreevich, MLB outfielder 1931–45
 - Frederick Kreismann, mayor of St. Louis 1909–13
 - Rich Kreitling, NFL wide receiver 1959–64
 - Gary Kremen, founder of Match.com
 - Raja Krishnamoorthi, lawyer, U.S. Representative (born in India)
 - John Kriza, ballet dancer
 - Ray Kroc, CEO of McDonald's, owned San Diego Padres
 - Egil Krogh, lawyer, aide to President Richard Nixon, Watergate figure
 - Ian Krol, MLB pitcher 2013-21
 - Candace Kroslak, actress, Ocean Ave.
 - Casey Krueger, pro soccer player, Chicago Red Stars
 - Bill Krueger, pitcher for eight MLB teams
 - Ernie Krueger, MLB catcher 1913–25
 - Gene Krupa, drummer, subject of film The Gene Krupa Story
 - Todd Krygier, hockey player for Washington Capitals and Anaheim Ducks
 - Mike Krzyzewski, basketball coach for Duke University, five NCAA championships, 2008 and 2012 Olympic gold medals, Hall of Fame
 - Steve Kuberski, forward for Boston Celtics and Milwaukee Bucks
 - Daniel Kucera, Catholic bishop, Illinois Benedictine president
 - Jonathan Kuck, speed skater, 2010 Winter Olympics silver medalist
 - John Kuenster, editor of Baseball Digest, author
 - Mickey Kuhn, actor
 - Toni Kukoc, Hall of Fame player and executive for Chicago Bulls (born in Croatia)
 - Jake Kumerow, NFL wide receiver
 - George Kunz, NFL lineman for Atlanta Falcons, Baltimore Colts
 - Stanley H. Kunz, thoroughbred breeder, U.S. Representative 1921–33 (born in Pennsylvania)
 - Irv Kupcinet, newspaper columnist, broadcaster
 - Karyn Kupcinet, actress, murder victim
 - C.J. Kupec, center for Michigan and Los Angeles Lakers
 - Bill Kurtis, television news journalist (born in Florida)
 - Emil Kush, pitcher for Chicago Cubs 1941–49
 - Sarah Kustok, sportscaster
 - Zak Kustok, quarterback for Northwestern
 - Michael Kutza, founder of Chicago International Film Festival
 - Ken Kwapis, TV and film director, The Office, The Sisterhood of the Traveling Pants, He's Just Not That Into You
 
L
La–Ld
- Walter LaBerge, Under Secretary of Army, Air Force, NATO
 - Ben LaBolt, political advisor, White House Communications Director
 - Harry Lachman, film director, Dante's Inferno, Our Relations
 - Bob Lackey, basketball player for Marquette and ABA's New York Nets
 - Ethel Lackie, swimmer, two gold medals in 1924 Summer Olympics
 - Matt LaCosse, NFL tight end 2015-21
 - Tanner Laczynski, NHL center
 - Tyler Ladendorf, MLB second baseman 2015-21
 - Carl Laemmle, motion picture mogul (born in Germany)
 - Carl Laemmle Jr., head of Universal Pictures
 - Carla Laemmle, silent-film actress
 - A.G. Lafley, CEO of Procter & Gamble (born in New Hampshire)
 - Jewel Lafontant, attorney, figure in George H. W. Bush administration
 - Garth Lagerwey, goalkeeper, executive in Major League Soccer
 - Kyung Lah, Tokyo-based international correspondent for CNN (born in South Korea)
 - Ray LaHood, politician (Republican), state and U.S. Representative, U.S. Secretary of Transportation 2009–13
 - Bill Laimbeer, NBA center 1979-93, two-time champion with Detroit Pistons, three-time WNBA champion coach (born in Massachusetts)
 - Frankie Laine, singer and actor, known for themes to 3:10 to Yuma, Gunfight at the O.K. Corral, Rawhide, Blazing Saddles
 - Jean La Lime, early Chicago settler (born in Canada)
 - Ricardo Lamas, mixed martial-arts fighter
 - Derek Lamely, golfer
 - Robert Lamm, musician, songwriter for band Chicago
 - Gene Lamont, MLB catcher, coach and manager
 - Robert P. Lamont, U.S. Secretary of Commerce 1927–32 (born in Michigan)
 - Amy Landecker, actress, A Serious Man, Louie, Transparent
 - Ann Landers (Ruth Crowley, Eppie Lederer), advice columnist
 - James Landis, noted power engineer
 - Jessie Royce Landis, actress, North by Northwest, To Catch a Thief
 - John Landis, film director, Animal House, The Blues Brothers, Trading Places, Michael Jackson's Thriller
 - Kenesaw Mountain Landis, judge, baseball commissioner, banned eight Black Sox (born in Ohio)
 - Reed G. Landis, combat pilot, son of Judge Landis
 - Margaret Landon, author, Anna and the King of Siam (born in Wisconsin)
 - Truman H. Landon, Air Force general (born in Missouri)
 - Hobie Landrith, catcher for seven MLB teams
 - Mabel Landry, four-time U.S. champion in long jump
 - Eric Lane, actor
 - Matteo Lane, comedian
 - Nora Lane, actress, The Man Hunter, The Cisco Kid
 - Tami Lane, Oscar-winning makeup artist
 - Will Lang Jr., war correspondent, bureau chief for Life magazine
 - Mary Lewis Langworthy, president, Chicago Woman's Club
 - Harris Laning, admiral
 - John Lankston, opera singer
 - Sherry Lansing, actress and CEO of Paramount Pictures
 - Lauren Lapkus, actress, Orange Is the New Black, Are You There, Chelsea?, Clipped, Jurassic World
 - Alison LaPlaca, actress, Open House, Madhouse
 - Angelo J. LaPietra, mobster with Chicago Outfit
 - John Lardner, war correspondent, New York sportswriter
 - Ring Lardner, early 20th Century sportswriter, author, composer, lyricist (born in Michigan)
 - Ring Lardner Jr., Oscar-winning screenwriter, Woman of the Year, The Cincinnati Kid, M*A*S*H
 - Gene La Rocque, U.S. Navy rear admiral
 - Rod La Rocque, actor, The Locked Door, Forbidden Paradise
 - Norm Larsen, industrial chemist, inventor of WD-40
 - René-Robert Cavelier, Sieur de La Salle, explorer (born in France)
 - Kirke La Shelle, reporter, editor, playwright, producer
 - Albert Lasker, advertising executive, co-owned Chicago Cubs 1916–25 (born in Germany)
 - Jonathan Latimer, author and screenwriter
 - Johnny Lattner, football player, Heisman Trophy winner for Notre Dame
 - William Lava, composer of animated film music, Looney Tunes
 - Arnold Laven, director and producer, The Rifleman, The Big Valley, Rough Night in Jericho, Sam Whiskey
 - Hazel Lavery, artist and model
 - Jackie LaVine, swimmer, 1952 Olympic bronze medalist
 - Ralph Lawler, radio-TV broadcaster of Los Angeles Clippers
 - Carol Lawrence, singer and actress
 - George R. Lawrence, photographer and aviator
 - Robert Henry Lawrence Jr., jet pilot and astronaut
 - Victor F. Lawson, publisher of Chicago Daily News 1876–1925
 - Don Laz, pole vaulter, silver medalist in 1952 Summer Olympics
 
Le–Lh
- Cloris Leachman, Oscar-winning, eight-time Emmy-winning actress, The Last Picture Show, Mary Tyler Moore, Young Frankenstein, 1946 Miss Illinois (born in Iowa)
 - Brett Lebda, NHL defenseman 2005–11
 - Mike Lebovitz, stand-up comedian
 - Pepi Lederer, silent-film actress
 - Ang Lee, Oscar-winning director, Illinois alumnus (born in Taiwan)
 - Doug Lee, NBA player 1991–95
 - Mary Lee, actress, Cowboy and the Senorita, South of the Border
 - Mike Lee, boxer
 - Russell Lee, photographer
 - Dan LeFevour, pro football quarterback
 - Joan Lefkow, judge (born in Kansas)
 - Lance LeGault, actor, The A-Team
 - Ernest de Koven Leffingwell, explorer
 - Natasha Leggero, comedian, judge on Last Comic Standing
 - Charlie Leibrandt, MLB pitcher 1979–93, 1985 World Series champion
 - Lefty Leifield, MLB pitcher 1905–20
 - Levi Leiter, co-founder of Marshall Field & Co., president of Art Institute of Chicago
 - Mark Leiter, pitcher for eight MLB teams
 - Charles LeMaire, Oscar-winning costume designer
 - John LeMay, actor, Friday the 13th: The Series (born in Minnesota)
 - Walt Lemon Jr., American player in Israel Basketball Premier League
 - Don Lenhardt, player for four MLB teams
 - Harry Lennix, actor, Dollhouse, The Blacklist, Matrix films
 - Thomas Lennon, actor, comedian, Reno 911!, The State, Viva Variety
 - Lance Lenoir, pro football player
 - Rick Lenz, actor, Hec Ramsey, Cactus Flower, The Shootist
 - Dutch Leonard, pitcher for four MLB teams
 - Jack E. Leonard, comedian
 - Meyers Leonard, NBA and Illinois center (born in Virginia)
 - Robert Z. Leonard, Oscar-nominated film director, The Great Ziegfeld, Pride and Prejudice, The Bribe
 - Leopold and Loeb, notorious murderers of 1924
 - Lawrence Leritz, dancer, actor
 - Leo Lerner, newspaper publisher
 - Jim Les, guard for four NBA teams, head coach of UC Davis
 - Mikel Leshoure, running back for Detroit Lions 2011–14
 - Amy Leslie, opera singer, journalist (born in Iowa)
 - Donald Leslie, inventor of Leslie speaker
 - Buddy Lester, comedian and actor, Ocean's 11, The Nutty Professor
 - Jerry Lester, comedian, television personality
 - Ronnie Lester, guard for Chicago Bulls and 1985 NBA champion Los Angeles Lakers (born in Mississippi)
 - Tim Lester, quarterback and head coach, Western Michigan
 - Tracy Letts, Tony-winning actor, playwright, screenwriter, August: Osage County (born in Oklahoma)
 - Brian Levant, film director, The Flintstones, Beethoven, Snow Dogs, Are We There Yet?
 - Max Levchin, co-founder of PayPal and Yelp (born in Ukraine)
 - Mel Leven, songwriter
 - Edward H. Levi, president of University of Chicago 1968-75, U.S. Attorney General 1975–77
 - Charles Levin, actor, Alice, Capital News
 - Gabe Levin, American-Israeli player in Israeli Basketball Premier League
 - Al Levine, pitcher for seven MLB teams
 - Samm Levine, actor, Freaks and Geeks
 - Ted Levine, actor, The Silence of the Lambs, Monk (born in Ohio)
 - King Levinsky, boxer, heavyweight contender
 - Steven Levitan, TV director, screenwriter and producer; creator of Just Shoot Me! and Modern Family
 - Steven Levitt, economist, author of Freakonomics
 - Marv Levy, coach and general manager for Buffalo Bills, member of Pro Football Hall of Fame
 - Greg Lewis, NFL wide receiver 2003–10
 - J. Hamilton Lewis, congressman for two states, U.S. Senator of Illinois (born in Virginia)
 - John L. Lewis, Illinois coal miner, president of United Mine Workers of America (born in Iowa)
 - Lena Morrow Lewis, suffragist, Socialist
 - Meade Lux Lewis, jazz musician
 - Monica Lewis, singer and actress, The Strip, The D.I., Excuse My Dust, Affair with a Stranger
 - Ramsey Lewis, radio personality and Grammy-winning jazz musician, "The 'In' Crowd"
 - J.C. Leyendecker, illustrator (born in Germany)
 
Li–Ln
- Anna Li, gymnast, NCAA champion for UCLA (born in Nevada)
 - Marcus Liberty, pro basketball player
 - George Lichty, cartoonist, Grin and Bear It
 - Dennis Lick, offensive tackle for Chicago Bears 1976–81
 - E. J. Liddell, NBA forward, two-time Illinois Mr. Basketball
 - Don Liddle, pitcher for 1954 World Series champion New York Giants
 - Jeffrey Lieber, TV writer and producer, Lost
 - Jennifer Lien, actress, Star Trek: Voyager
 - DeAndre Liggins, pro basketball player
 - Lori Lightfoot, 56th Mayor of Chicago (born in Ohio)
 - Anita Lihme, princess of Bohemia
 - David E. Lilienthal, chairman, Atomic Energy Commission 1946–50
 - Arlene Limas, world and Olympic champion in taekwondo
 - Abbey Lincoln, singer and actress
 - Abraham Lincoln, 16th President of the United States, Illinois lawyer and legislator, writer of Gettysburg Address, issuer of Emancipation Proclamation (born in Kentucky)
 - Abraham Lincoln II, grandson of Abraham Lincoln
 - Jessie Harlan Lincoln, granddaughter of Abraham Lincoln
 - Mamie Lincoln, granddaughter of Abraham Lincoln
 - Mary Todd Lincoln, Abe Lincoln's wife (born in Kentucky, died in Illinois)
 - Robert Todd Lincoln, attorney, U.S. Ambassador to United Kingdom, Secretary of War, President of Pullman Company, Abe Lincoln's son
 - Tad Lincoln, youngest son of Abe Lincoln, died at 18
 - Thomas Lincoln, father of Abe Lincoln, lived in Illinois 1831–51 (born in Virginia)
 - Katie Lind, pro soccer player
 - Mike Lind, NFL and Notre Dame fullback
 - Edward Lindberg, athlete, relay gold medalist in 1912 Summer Olympics
 - Jim Lindeman, MLB outfielder 1986–94
 - Fannie B. Linderman, educator, entertainer, and writer
 - Charles Magnus Lindgren, shipping executive (born in Sweden)
 - John R. Lindgren, banking executive, son of Charles M. Lindgren
 - Justa Lindgren, football player for Illinois 1898–1901, coach of 1904 Big Ten champions
 - Benjamin F. Lindheimer, horse racing, owner of Washington Park Race Track and Arlington Park
 - Vachel Lindsay, poet
 - Chuck Lindstrom, catcher, tripled in only MLB at-bat
 - Freddie Lindstrom, Hall of Fame third baseman
 - Ed Linke, MLB pitcher 1933–38
 - Art Linson, producer, The Untouchables, Heat, Fight Club, Into the Wild
 - Dan Lipinski, politician (Democrat), U.S. Representative 2005-21
 - William O. Lipinski, politician (Democrat), U.S. Representative 1993–2005
 - Clara Lipman, 19th Century stage actress
 - Johnny Lira, boxer, USBA lightweight champ
 - Peter Lisagor, journalist
 - Rusty Lisch, quarterback for Notre Dame and St. Louis Cardinals
 - Jerome Edward Listecki, archbishop of Milwaukee, Wisconsin
 - Little Walter, blues musician (born in Louisiana)
 - J. J. Liu, professional poker player (born in California)
 - Robert Livingston, actor, The Three Mesquiteers
 - Shaun Livingston, NBA forward 2004-19, three-time champion and executive with Golden State Warriors
 - Danny Lloyd, actor, The Shining
 - Scott Lloyd, NBA player 1976-82
 - Vince Lloyd, baseball broadcaster
 
Lo–Lp
- Dick Locher, Pulitzer-winning cartoonist, writer-artist of Dick Tracy
 - Allan Loeb, screenwriter, Wall Street: Money Never Sleeps, The Switch
 - Marshall Loeb, magazine editor
 - Kelly Loeffler, U.S. Senator of Georgia 2020-21
 - Frank J. Loesch, chief of Chicago Crime Commission (born in New York)
 - Nils Lofgren, musician, member of Bruce Springsteen E Street Band
 - Johnny Loftus, Hall of Fame jockey, two-time Kentucky Derby winner, 1919 Triple Crown
 - David Logan, 19th Century mayor of Portland, Oregon
 - Janice Logan, actress, Opened by Mistake, Dr. Cyclops
 - John A. Logan, politician (Democrat and Republican), Civil War general, U.S. Representative, U.S. Senator
 - John Alexander Logan Jr., Medal of Honor winner, killed in combat
 - John Logan, screenwriter, Gladiator, The Aviator, Skyfall (born in California)
 - Stephen T. Logan, law partner of Abe Lincoln
 - Gary Loizzo, musician with The American Breed
 - Joseph Lombardo, organized crime figure
 - Dutch Lonborg, basketball coach, Northwestern all-time leader in victories, Hall of Fame
 - Chuck Long, quarterback and coach, Heisman Trophy runner-up, College Football Hall of Fame (born in Oklahoma)
 - Fred T. Long, baseball player, football coach
 - Herman Long, MLB infielder 1889–1904
 - Richard Long, actor, The Big Valley, Nanny and the Professor, Bourbon Street Beat, House on Haunted Hill
 - Shelley Long, actress, Second City, Northwestern, Cheers, Troop Beverly Hills, The Brady Bunch Movie (born in Indiana)
 - Frank Loomis, hurdler, gold medalist in 1920 Summer Olympics
 - Horatio G. Loomis, a founder of Chicago Board of Trade (born in Vermont)
 - John Patrick Looney, gangster from Rock Island, inspired character in Road to Perdition
 - Al Lopez, manager of White Sox 1950s, '60s (born in Florida)
 - Ramón E. López, space physicist
 - Robert Lord, Oscar-winning screenwriter
 - Robert Lorenz, film producer, American Sniper, Mystic River
 - Fred Lorenzen, auto racer, winner of 1965 Daytona 500
 - William Lorimer, banker and politician
 - Dave Losso, stand-up comedian
 - George Lott, five-time U.S. doubles champion, 1931 US Open finalist
 - Julia Louis-Dreyfus, actress, Second City, The Practical Theatre Company, Northwestern, Seinfeld (born in New York)
 - Lee Loughnane, musician with band Chicago
 - Tony Lovato, musician, member of band Mest
 - Bob Love, three-time All-Star for Chicago Bulls (born in Louisiana)
 - John Arthur Love, Governor of Colorado 1963–73
 - Elijah Lovejoy, abolitionist, editor (born in Maine)
 - Owen Lovejoy, minister, abolitionist, U.S. Representative (born in Maine)
 - Frank Orren Lowden, politician (Republican), U.S. Representative, Governor of Illinois 1917–21 (born in Minnesota)
 - Grover Lowdermilk, MLB pitcher 1909–20 (born in Indiana)
 - Fred Lowenthal, college football coach
 - Lynn Lowry, actress
 - Alexander Loyd, Mayor of Chicago 1840–41 (born in New York)
 - Jewell Loyd, basketball player, top pick of 2015 WNBA draft, two-time WNBA champion, 2020 Olympic gold medalist
 
Lq–Lz
- Scott W. Lucas, lawyer, U.S. Representative, U.S. Senator 1939-51
 - Sid Luckman, quarterbacked Chicago Bears to four NFL championships (born in New York)
 - Ludacris (Christopher Bridges), Grammy Award-winning rapper and actor, The Fast and the Furious
 - William H. Luers, ambassador to Czechoslovakia, Venezuela
 - Larry Lujack, radio personality (born in Iowa)
 - Ned Luke, actor, Grand Theft Auto V
 - Deanna Lund, actress, Land of the Giants
 - Helen Lundeberg, painter
 - Carl Lundgren, MLB pitcher 1902–09
 - Paul Lusk, basketball coach
 - Hamilton Luske, Oscar-winning animator, Mary Poppins
 - Greg Luzinski, outfielder for Chicago White Sox and 1980 World Series champion Philadelphia Phillies
 - Abe Lyman, bandleader
 - Jane Lynch, actress and comedian, Glee, The 40-Year-Old Virgin, Julie & Julia, A Mighty Wind, Hollywood Game Night
 - John Lynch, NFL defensive back 1993-2008, Super Bowl XXXVII champion, Hall of Fame, general manager of San Francisco 49ers
 - Jordan Lynch, quarterback for Northern Illinois and 2015 CFL champion Edmonton Eskimos
 - Bird Lynn, catcher for 1917 World Series champion White Sox
 - Fred Lynn, outfielder for Boston Red Sox, California Angels, 1975 American League MVP
 - Ginger Lynn, adult-film actress
 - Janet Lynn, five-time U.S. champion figure skater
 - Marjorie Lynn, singer, National Barn Dance (born in Wisconsin)
 - Ted Lyons, 21-year pitcher for Chicago White Sox, member of Hall of Fame (born in Louisiana)
 - Evan Lysacek, figure skater, 2010 Winter Olympics gold medalist and 2009 world champion, Sullivan Award winner
 
M
Maa–Mag
- Bernie Mac, actor, comedian, The Bernie Mac Show, Mr. 3000, Bad Santa, Ocean's Eleven and its sequels
 - Charles MacArthur, Oscar-winning screenwriter, Chicago journalist, playwright (born in Pennsylvania)
 - Hayes MacArthur, comedian, actor, writer, Angie Tribeca, Perfect Couples, The Game Plan
 - Franklyn MacCormack, radio personality (born in Iowa)
 - Charles B. Macdonald, won first U.S. Amateur tournament, built Chicago Golf Club (born in Canada)
 - Hazel MacDonald, film critic and war correspondent
 - Elaine "Spanky" MacFarlane, singer with Spanky and Our Gang
 - Justina Machado, actress, Six Feet Under, Missing, Three Rivers, One Day at a Time
 - Christy Mack, model, stripper, porn actress
 - Helen Mack, actress, His Girl Friday, The Son of Kong, She
 - Peter F. Mack Jr., pilot, seven-term U.S. Representative
 - Sam Mack, guard for five NBA teams
 - Pete Mackanin, manager for Cincinnati Reds, Philadelphia Phillies
 - Felix Mackiewicz, MLB outfielder 1941–47
 - Rob Mackowiak, outfielder for Pittsburgh Pirates and White Sox
 - Archibald MacLeish, poet and writer, three-time Pulitzer Prize winner
 - Fred MacMurray, actor, My Three Sons, Double Indemnity, The Caine Mutiny, The Absent-Minded Professor, The Apartment
 - Tress MacNeille, voice actress, The Simpsons, Futurama, Animaniacs (born in California)
 - Bart Macomber, halfback for Illinois 1914–15 national champions
 - Earle S. MacPherson, automotive engineer, developed MacPherson strut
 - Franklin MacVeagh, banker, U.S. Secretary of the Treasury 1909–13 (born in Pennsylvania)
 - John Macy, civil service chief for Presidents Eisenhower and Kennedy
 - Martin B. Madden, U.S. Representative 1905–28 (born in England)
 - David M. Maddox, retired U.S. Army four-star general
 - Amy Madigan, Oscar-nominated actress, Carnivàle, Field of Dreams, Uncle Buck, Pollock, Gone Baby Gone
 - Edward Rell Madigan, U.S. Representative 1973–91, U.S. Secretary of Agriculture 1991–93
 - Lisa Madigan, Attorney General of Illinois 2003-19
 - Michael Madigan, state representative 1971-2021, Speaker of House 1997-2021, state Democratic Party chairman
 - Slip Madigan, college football player, three-sport coach
 - Cleo Madison, silent-film actress
 - Sarah Danielle Madison, actress
 - Bill Madlock, MLB third baseman 1973-88, four-time batting champion
 - Michael Madsen, actor, Reservoir Dogs, Kill Bill, The Natural, Thelma & Louise, Donnie Brasco, The Hateful Eight
 - Virginia Madsen, Oscar-nominated actress, Sideways, Candyman, Dune, The Number 23, The Rainmaker, Joy
 - Mike Magac, NFL lineman 1960–66
 - Mike Magee, soccer player for Chicago Fire
 - Corey Maggette, forward for six NBA teams
 - Magic Sam, blues musician (born in Mississippi)
 - Elizabeth Magie, inventor of game that became Monopoly
 - Francis Joseph Magner, Catholic bishop
 - Sandra Magnus, astronaut, aboard final Space Shuttle
 - Christine Magnuson, swimmer, two-time Olympic medalist
 
Mah–Maq
- Ron Mahay, relief pitcher for eight MLB teams
 - Maureen Maher, host of CBS series 48 Hours Mystery (born in Michigan)
 - John Lee Mahin, screenwriter, Treasure Island, Dr. Jekyll and Mr. Hyde, Show Boat
 - Jock Mahoney, actor, Tarzan films, Yancy Derringer
 - John Mahoney, actor, Marty Crane on Frasier, Moonstruck, Barton Fink, Primal Fear, Eight Men Out (born in England)
 - Vivian Maier, photographer, Finding Vivian Maier (born in New York)
 - Gil Mains, defensive tackle for Detroit Lions 1953–61
 - J. Earl Major, judge, U.S. Representative
 - Rebecca Makkai, novelist and short-story writer
 - Karl Malden, Oscar-winning actor, On the Waterfront, A Streetcar Named Desire, Gypsy, The Cincinnati Kid, Patton, The Streets of San Francisco
 - Terrence Malick, Oscar-nominated filmmaker, Days of Heaven, The Thin Red Line, Tree of Life
 - John Malkovich, Oscar-nominated actor, Con Air, In the Line of Fire, Rounders, Secretariat, RED, Being John Malkovich
 - Sax Mallard, jazz musician
 - Dorothy Malone, Oscar-winning actress, The Big Sleep, Written on the Wind, Man of a Thousand Faces, Peyton Place
 - Frank Maloney, college football coach
 - Jasper A. Maltby, Civil War general, gunsmith (born in Ohio)
 - David Malukas, auto racer
 - David Mamet, Oscar-nominated screenwriter, Pulitzer Prize-winning playwright, director, Glengarry Glen Ross, The Verdict, Wag the Dog, Hoffa, The Untouchables
 - Gail Mancuso, TV director, Roseanne, Modern Family, Friends
 - Sammy Mandell, lightweight boxing champion 1926–30
 - Larry Manetti, actor, Magnum, P.I.
 - Harry Manfredini, film composer
 - Camryn Manheim, actress, The Practice, Ghost Whisperer, Law & Order
 - Lewis Manilow, real estate developer, co-founder of Museum of Contemporary Art, Chicago
 - Sebastian Maniscalco, stand-up comedian and actor, Green Book, About My Father
 - Carol Mann, golfer, won 38 LPGA tournaments (born in New York)
 - James Robert Mann, politician (Republican), attorney, Chicago alderman, U.S. Representative 1897–1922
 - Michael Mann, television and Oscar-nominated film director, Miami Vice, Heat, The Insider, Manhunter, Collateral, Ali
 - Joe Mantegna, actor, voice actor, Criminal Minds, The Godfather Part III, House of Games, Joan of Arcadia, The Rat Pack, The Simpsons
 - Joe Mantello, actor and Broadway director
 - Jay Manuel, make-up artist, America's Next Top Model
 - Ray Manzarek, co-founder and keyboardist for The Doors
 
Mar–Mas
- Paul Marcinkus, archbishop and president of Vatican Bank
 - Carol Marin, television and newspaper journalist
 - Edna Marion, actress
 - Shawn Marion, NBA forward 1999-2015, four-time All-Star
 - Mary Beth Marley, figure skater
 - Jerry Markbreit, professional football referee
 - Gene Markey, screenwriter, decorated naval officer, Chicago Academy of Fine Arts alumnus, husband of Hedy Lamarr and Myrna Loy
 - Morris Markin, founder of Checker Motors Company, owner of Yellow Cab (born in Russia)
 - Harry Markowitz, Nobel Prize-winning economist
 - Clayton Marks, educator, soldier, banker and historian
 - Brit Marling, writer, actress, Another Earth, Arbitrage, Babylon
 - Jess Marlow, television journalist
 - Jacques Marquette, 17th Century explorer (born in France)
 - Frank Clarence Mars, candy maker (born in Minnesota)
 - Forrest Mars Jr., billionaire Mars family scion
 - Kenneth Mars, actor, Young Frankenstein, The Producers, What's Up, Doc?, The Little Mermaid
 - Albert L. Marsh, metallurgist, co-inventor of nichrome
 - Benjamin F. Marsh, railroad czar, Civil War soldier, U.S. Representative
 - Frank Lewis Marsh, Seventh-day Adventist biologist, educator and young Earth creationist
 - Fred Marsh, MLB infielder 1949–56
 - George Marsh, decorated Civil War soldier
 - Benjamin H. Marshall, architect of Chicago hotels
 - Francis Marshall, brigadier general, World War I
 - George Marshall, film director, You Can't Cheat an Honest Man, Destry Rides Again, Houdini, How the West Was Won
 - Joan Marshall, actress
 - Jim Marshall, MLB first baseman 1958–62
 - Mike Marshall, outfielder for four MLB teams
 - Samuel S. Marshall, lawyer, 19th Century politician
 - William Marshall, singer, bandleader, husband of Ginger Rogers
 - June Martel, actress, Santa Fe Stampede, Forlorn River
 - Andra Martin, actress, The Thing That Couldn't Die, Up Periscope
 - Billy Martin, tennis player and coach
 - Cecil Martin, NFL fullback 1999–2003
 - Chuck Martin, football head coach, Miami of Ohio
 - Cuonzo Martin, basketball head coach, Cal, Tennessee, Missouri
 - James Stewart Martin, Civil War general, U.S. Representative
 - LaRue Martin, center for Loyola and Portland Trail Blazers, top pick of 1972 NBA draft
 - Lynn Morley Martin, U.S. Representative 1981–91, U.S. Secretary of Labor 1991–93
 - Marcella Martin, actress, Gone With the Wind, West of Tombstone
 - Nan Martin, actress, Goodbye, Columbus, The Other Side of the Mountain, The Drew Carey Show
 - Todd Martin, pro tennis player, U.S. Open and Australian Open finalist
 - Richard Martini, writer and director, Cannes Man
 - Carl Shipp Marvel, organic chemist
 - Dick Marx, jazz musician, ad jingle writer
 - Richard Marx, singer and songwriter
 - Russell Maryland, NFL defensive tackle, College Football Hall of Fame
 - Ron Masak, actor, Murder, She Wrote
 - Ella Masar, pro soccer player
 - Phil Masi, MLB catcher 1939–52
 - Bobby Joe Mason, basketball player for Bradley and Harlem Globetrotters
 - Noah M. Mason, politician (Republican), U.S. Representative 1937–63 (born in Wales)
 - Roswell B. Mason, mayor during Great Chicago Fire (born in New York)
 - William E. Mason, U.S. Representative, U.S. Senator (born in New York)
 - Michael Masser, songwriter, "Greatest Love of All"
 - Edgar Lee Masters, author and poet (born in Kansas)
 - Mary Elizabeth Mastrantonio, Oscar-nominated actress, Scarface, The Color of Money, The Abyss, The Perfect Storm, Limitless
 
Mat–Maz
- Mary Matalin, presidential advisor, television commentator, author
 - Carole Mathews, actress and radio personality
 - Milton W. Mathews, 19th Century publisher and politician
 - T.J. Mathews, MLB pitcher 1995–2002
 - Art Mathisen, basketball player for Illinois
 - Jake Matijevic, NASA engineer, developed Mars rovers
 - Marlee Matlin, Oscar-winning actress, Children of a Lesser God
 - Thad Matta, head basketball coach for Ohio State, Butler
 - Joel Aldrich Matteson, railroad executive, Governor of Illinois 1853–57 (born in New York)
 - Clyde Matthews, college football coach
 - Denny Matthews, baseball broadcaster (born in Florida)
 - Wid Matthews, baseball executive
 - Ken Mattingly, astronaut and admiral
 - Carl Mauck, center for four NFL teams, coach
 - John Mauer, college basketball coach
 - Bill Mauldin, Pulitzer Prize-winning cartoonist, Willie and Joe (born in New Mexico)
 - Jeff Mauro, television personality, Food Network
 - Jason Maxiell, NBA forward 2005–15
 - Dal Maxvill, MLB infielder, played in five World Series
 - Holle Thee Maxwell, singer and songwriter
 - Lucien Maxwell, hunter, owned ranch where Billy the Kid was killed
 - Philip Maxwell, 19th Century doctor, namesake of Chicago's Maxwell Street (born in Vermont)
 - William Keepers Maxwell, fiction editor of New Yorker 1936–75
 - Tiny Maxwell, football player, sportswriter, namesake of Maxwell Award
 - Donald May, actor, The Roaring 20s
 - Elaine May, actress, director, Oscar-nominated screenwriter, alumna of University of Chicago and Second City (born in Pennsylvania)
 - George S. May, businessman, golf promoter
 - John L. May, archbishop of St. Louis 1980–92
 - William L. May, politician, first mayor of Springfield, Illinois
 - Marilyn Maye, singer (born in Kansas)
 - Oscar F. Mayer, founder of Oscar Mayer meat company (born in Germany)
 - Oscar G. Mayer Sr., chairman of Oscar Mayer 1955–65
 - Oscar G. Mayer Jr., chairman of Oscar Mayer 1966–2009
 - Benjamin Mayfield, cowboy, outlaw
 - Curtis Mayfield, soul, R&B and funk singer, songwriter, Rock and Roll Hall of Fame, Grammy Legend Award
 - William Mayfield, cattleman, militia leader (born in Tennessee)
 - Jackie Mayo, outfielder for Philadelphia Phillies 1948–53
 - Margaret Mayo, playwright
 - Stanley Mazor, co-inventor of first microprocessor
 - Rob Mazurek, musician
 - Marin Mazzie, Tony Award-nominated actress
 
Mca–Mcd
- Zach McAllister, pitcher for Cleveland Indians 2011-18
 - James McAndrews, building commissioner, nine-term U.S. Representative (born in Rhode Island)
 - Brian McBride, soccer player, U.S. national team, MSL and English Premier League
 - Chi McBride, actor, Hawaii Five-0, I, Robot, The John Larroquette Show, Boston Public, Human Target
 - Steve McCall, drummer
 - Oliver McCall, boxer, WBC heavyweight champ 1994–95
 - Mercedes McCambridge, Oscar-winning actress, All the King's Men, Giant, Johnny Guitar, The Exorcist
 - Terrence McCann, freestyle wrestling gold medalist at 1960 Summer Olympics
 - Mel McCants, NBA player for Los Angeles Lakers 1989–90
 - Justin McCareins, NFL wide receiver 2001–08
 - Larry McCarren, center for Green Bay Packers 1973–84, commentator, Packers Hall of Fame
 - Alex McCarthy, MLB infielder 1910–17
 - Jenny McCarthy, model, actress, author, activist, Scream 3, Dirty Love, Witless Protection, The View
 - Johnny McCarthy, MLB first baseman 1934–48
 - Melissa McCarthy, Emmy-winning, Oscar-nominated actress, Mike & Molly, Bridesmaids, Identity Thief, Tammy
 - Peggy McCarthy, rowing bronze medalist, 1976 Olympics
 - Tim McCarthy, wounded Secret Service agent for Ronald Reagan
 - Constance McCashin, actress, Knots Landing
 - Ed McCaskey, chairman of Chicago Bears 1983–1999
 - George McCaskey, chairman of Chicago Bears
 - Michael McCaskey, chairman of Chicago Bears 1999–2011
 - Virginia Halas McCaskey, owner of Chicago Bears
 - Hazel A. McCaskrin, politician
 - Harry M. McCaskrin, politician
 - Sergio McClain, basketball player for Illinois
 - Gerald McClellan, middleweight boxing champion 1991–95
 - Kathleen McClellan, actress, 1988 Miss Illinois Teen USA
 - John Alexander McClernand, Civil War general, advisor to Presidents Lincoln and Grant, U.S. Representative
 - Robert McClory, U.S. Representative 1963–83
 - Alice Moore McComas, writer, editor, lecturer, social reformer
 - Brooks McCormick, CEO of International Harvester
 - Mike McCormack, Hall of Fame NFL player, coach and executive
 - Cyrus Hall McCormick, businessman, inventor of McCormick Reaper (born in Virginia)
 - Edith Rockefeller McCormick, socialite, patron of opera and Brookfield Zoo
 - Harold Fowler McCormick, chairman of International Harvester, husband of Edith Rockefeller
 - Katharine McCormick, biologist, suffragist, philanthropist (born in Michigan)
 - Robert R. McCormick, newspaper publisher and philanthropist
 - Ruth Hanna McCormick, suffragist, U.S. Representative 1929–31
 - Walter McCornack, first football coach for Northwestern
 - Joseph McCoy, cattle baron
 - LisaRaye McCoy, actress, All of Us, Single Ladies
 - Keith McCready, professional pool player, actor in The Color of Money
 - Johnston McCulley, author, creator of Zorro
 - John T. McCutcheon, cartoonist
 - Jim McDermott, U.S. Representative of Washington 1989-2017
 - Darren W. McDew, U.S. Air Force general
 - Glenn McDonald, member of 1976 NBA champion Boston Celtics
 - Ariel McDonald, basketball player; 2000 Israeli Basketball Premier League MVP
 - Robert A. McDonald, chairman and CEO of Procter & Gamble, U.S. Secretary of Veterans Affairs 2014-17
 - John McDonough, president and CEO of Chicago Blackhawks 2007-20
 - Frances McDormand, Oscar and Emmy-winning actress, Fargo, Blood Simple, Almost Famous, Moonrise Kingdom, Olive Kitteridge, Nomadland
 
Mce–Mcz
- Ray McElroy, NFL defensive back 1995–2001
 - Frank McErlane, organized crime figure
 - Tatyana McFadden, wheelchair athlete, Paralympian, winner of Boston and Chicago marathons (born in Russia)
 - Chappie McFarland, MLB pitcher 1902–06
 - Packey McFarland, lightweight boxer
 - T. J. McFarland, MLB relief pitcher
 - Bill McGee, MLB pitcher 1935–42
 - JaVale McGee, basketball player, three-time NBA champion, 2020 Olympics gold medalist
 - Ralph McGehee, football player for Notre Dame, officer for CIA
 - Carla McGhee, basketball player, two NCAA championships, 1996 Olympic gold medalist
 - Tyler McGill, swimmer, gold medalist at 2012 London Olympics
 - Joe McGinnity, MLB player in Hall of Fame
 - William P. McGivern, novelist, books became films The Big Heat, Odds Against Tomorrow
 - Elizabeth McGovern, Oscar-nominated actress, Ragtime, Ordinary People, Once Upon a Time in America, The Handmaid's Tale, Downton Abbey
 - Roxana McGowan, silent-film actress
 - Bob McGrath, television personality, Sesame Street
 - Lamar McGriggs, pro football player
 - Aaron McGruder, cartoonist, The Boondocks
 - Roger McGuinn, musician, The Byrds
 - Don McGuire, actor, Oscar-nominated screenwriter
 - Kathryn McGuire, silent-film actress, Sherlock Jr.
 - Jack McGurn, gangster with Chicago Outfit (born in Italy)
 - Donald McHenry, Ambassador to United Nations (born in Missouri)
 - William McHenry, 19th Century soldier and politician
 - Collin McHugh, MLB pitcher, member of 2017 World Series champion Houston Astros
 - Tim McIlrath, musician, Rise Against
 - Adam McKay, performer for Second City, screenwriter of Anchorman, director of The Big Short (born in Pennsylvania)
 - Lafe McKee, actor[17]
 - William Parker McKee, president of Shimer College[18]
 - Kevin McKenna, basketball player and coach
 - Raymond S. McKeough, U.S. Representative 1935–45[19]
 - William B. McKinley, U.S. Representative 1905–21, Senator 1921–26[20]
 - Billy McKinney, NBA and Northwestern player, mayor of Zion, Illinois
 - Denny McLain, pitcher, 31-game winner for 1968 World Series champion Detroit Tigers
 - John McLean, 19th Century U.S. Senator (born in North Carolina)
 - Frederic McLaughlin, first owner of Chicago Blackhawks
 - Claude McLin, saxophonist
 - Greg McMahon, college and NFL assistant coach
 - Jim McMahon, quarterback of Super Bowl XX champion Chicago Bears (born in New Jersey)
 - Sherrick McManis, NFL cornerback
 - James McManus, professional poker player, author
 - Marty McManus, MLB infielder 1920–34
 - Tom McManus, linebacker, Jacksonville Jaguars 1995–99
 - William Edward McManus, Roman Catholic bishop
 - Sherman McMaster, Wild West outlaw and lawman
 - Neysa McMein, illustrator and painter
 - Steve McMichael, pro football player and coach, wrestler, radio personality (born in Texas)
 - Ernie McMillan, offensive tackle for St. Louis Cardinals 1961–74
 - Bob McMillen, player and coach, Arena Football League
 - Jim McMillen, guard for 1923 Illinois national champions, Chicago Bears
 - Rolla C. McMillen, lawyer, U.S. Representative 1944–51
 - Mary Ann McMorrow, judge, Supreme Court of Illinois 1992-2006
 - Donovan McNabb, six-time Pro Bowl quarterback for Philadelphia Eagles, Washington Redskins, TV commentator
 - Jerel McNeal, all-time leading scorer for Marquette basketball
 - Barbara McNair, singer, television personality and actress, Change of Habit, They Call Me Mister Tibbs!
 - Andrew McNally, founder of Rand McNally company in 1868 (born in Northern Ireland)
 - John McNaughton, film and TV director, Wild Things, Mad Dog and Glory, Homicide: Life on the Street
 - Don McNeill, radio personality
 - Marcus McNeill, offensive tackle for San Diego Chargers 2006–11
 - James McNerney, CEO of Boeing, 3M
 - John McNulta, Civil War general, U.S. Representative (born in New York)
 - William Slavens McNutt, screenwriter, Huckleberry Finn
 - James McParland, Chicago-based Pinkerton's detective, infiltrated Molly Maguires (born in Ireland)
 - Jimmy McPartland, big-band cornet player
 - Ryan McPartlin, actor, Chuck, Living With Fran
 - Corey McPherrin, television journalist
 - Samuel McRoberts, U.S. Attorney under Andrew Jackson, U.S. Senator
 - Margaret McWade, actress, Mr. Deeds Goes to Town
 - Doug McWeeny, MLB pitcher 1921–30
 - Paulette McWilliams, singer
 
Md–Mh
- George J. Mecherle, founder of State Farm Insurance
 - David Meckler, ice hockey player
 - Joseph Medill, publisher, Mayor of Chicago 1871–73 (born in Canada)
 - Chris Medina, singer-songwriter, American Idol contestant
 - Mark Medoff, playwright, screenwriter, Children of a Lesser God
 - Patrick Meek, speed skater
 - Jayson Megna, NHL forward (born in Florida)
 - Bill Mehlhorn, golfer, 1924 Western Open champion, third in U.S. Open
 - Garry Meier, radio personality
 - Katie Meier, basketball player for Duke, coach at Miami
 - Merrill C. Meigs, pilot, newspaper executive, Meigs Field named for him
 - Leo Melamed, CEO of Chicago Mercantile Exchange
 - Gene Melchiorre, basketball player, 1951 top NBA draft pick, banned for point-shaving scandal
 - Al Melgard, organist at Chicago Stadium 1930-74
 - Ski Melillo, MLB infielder 1926–37
 - Chuck Mellor, winner of 1925 Boston Marathon
 - Rich Melman, restaurateur
 - Lester Melrose, music producer
 - Walter Melrose, music producer
 - Bill Melton, MLB third baseman, sportscaster (born in Mississippi)
 - Daniel Meltzer, Harvard law professor, Barack Obama deputy counsel
 - David O. Meltzer, professor of medicine
 - Rachel Melvin, actress, Dumb and Dumber To
 - Rashaan Melvin, NFL cornerback
 - John Willis Menard, first African-American elected to U.S. Congress, 1858
 - Pierre Menard, fur trader, Illinois' first lieutenant governor (born in Canada)
 - Carol Mendelsohn, TV executive, CSI and CSI:NY
 - Rashard Mendenhall, running back for Illinois and Super Bowl XLIII champion Pittsburgh Steelers
 - Alex Meneses, actress, model, Dr. Quinn, Medicine Woman, Everybody Loves Raymond
 - Sid Mercer, sportswriter
 - Joanna Merlin, casting director, actress
 - Charles Edward Merriam, political scientist, professor (born in Iowa)
 - Doris Merrick, actress, The Big Noise, The Counterfeiters
 - Ahmad Merritt, NFL wide receiver 2000–08
 - Aries Merritt, hurdler, 2012 London Olympics gold medalist
 - Bus Mertes, football coach, Kansas State, Drake
 - Robert Meschbach, soccer player
 - Laurie Metcalf, Emmy and Tony Award-winning, Oscar-nominated actress, Roseanne, The Conners, JFK, Internal Affairs, Toy Story, Lady Bird
 - Ralph Metcalfe, sprinter, 100-meter silver medalist at 1936 Summer Olympics; politician (Democrat), U.S. Representative
 - Linda Metheny, gymnast
 - Bert Metzger, football player
 - Dick Meyer, journalist, CBS News, BBC America and NPR
 - Joey Meyer, head basketball coach at DePaul 1984–97
 - John Meyer, pro football player and coach
 - Ray Meyer, Basketball Hall of Fame coach for DePaul from 1942–84
 - Russ Meyer, MLB pitcher 1946–59
 - Seth Meyers, comedian, actor, and television personality
 - Mezz Mezzrow, jazz musician
 
Mi–Mn
- Patrick Michaels, climatologist, senior fellow at Cato Institute
 - M. Alfred Michaelson, banker, U.S. Representative (born in Norway)
 - Chris Michalak, MLB pitcher 1998-2006
 - Laura Michalek, won 1979 Chicago Marathon at age 15
 - Robert H. Michel, politician (Republican), U.S. Representative for 38 years, House Minority Leader 1981–95
 - Lucia Mida, golfer
 - Ray Middleton, actor, Hurricane Smith, Lady for a Night, 1776
 - Ludwig Mies van der Rohe, modernist architect (born in Prussia)
 - Richard W. Mies, admiral, head of U.S. Strategic Command 1998–2001
 - Ed Mikan, pro and DePaul basketball player
 - George Mikan, Hall of Fame basketball center, DePaul and five-time NBA champion Minneapolis Lakers
 - Stan Mikita, 22-year player for Chicago Blackhawks, member of Hockey Hall of Fame (born in Canada)
 - Abner Mikva, judge, politician (Democrat), U.S. Representative, White House Counsel to Bill Clinton
 - Darius Miles, forward for four NBA teams
 - Gina Miles, singer, winner of The Voice season 23
 - Penelope Milford, Oscar-nominated actress, Coming Home
 - Adam Miller, basketball player
 - Bob Miller, pitched in MLB at 17
 - Bob Miller, broadcaster in Hockey Hall of Fame
 - Bobby Miller, MLB pitcher
 - Jack Miller, 12-year U.S. Senator of Iowa
 - Jesse Miller, musician
 - Mary Miller, U.S. Representative
 - Otis L. Miller, MLB infielder 1927–32
 - Patrick Miller, American player in Israeli Basketball Premier League
 - Red Miller, head coach of Denver Broncos 1977–80
 - Ron Miller, songwriter, "For Once in My Life"
 - Steve Miller, track coach, athletic director, Nike executive, PBA director
 - Terry Miller, NFL linebacker 1970–74
 - Ward Miller, MLB outfielder 1909–17
 - James Millhollin, character actor
 - Wally Millies, MLB catcher 1934–41
 - Robert Andrews Millikan, experimental physicist and Nobel laureate
 - Isaac Lawrence Milliken, blacksmith, alderman, Mayor of Chicago 1854–55 (born in Maine)
 - Donna Mills, actress, Knots Landing, Play Misty for Me
 - Douglas R. Mills, basketball player, coach and athletic director for University of Illinois
 - Phoebe Mills, gymnast, 1988 Olympic bronze medalist
 - Sherrill Milnes, opera singer
 - Bob Miner, co-founder of Oracle Corporation
 - Steve Miner, film and TV director, Friday the 13th Part 2, Lake Placid, Day of the Dead
 - Vincente Minnelli, Oscar-winning film director, An American in Paris, Gigi, The Band Wagon, Lust for Life, The Bad and the Beautiful, Father of the Bride, Some Came Running
 - Minnie Miñoso, Hall of Fame outfielder, batted for White Sox in 1950s–1980s (born in Cuba)
 - Martha Minow, dean of Harvard Law School
 - Bob Mionske, attorney, Olympic and professional bicycle racer
 - Chad Mirkin, professor, Northwestern
 - Pat Misch, MLB pitcher 2006–11
 - Jacquelyn Mitchard, author, The Deep End of the Ocean
 - Joan Mitchell, artist
 - John Mitchell, labor leader
 - John Francis Mitchell, president and COO of Motorola 1980–1995
 - Johnny Mitchell, NFL tight end 1992–96
 - Kel Mitchell, comedian and actor
 - Nicole Mitchell, flautist (born in New York)
 - Roscoe Mitchell, jazz saxophonist
 - Matt Mitrione, mixed martial artist
 
Mo–Mt
- Tony Moeaki, NFL tight end 2010-16
 - Joe Moeller, MLB pitcher and scout
 - Doug Moench, comic book writer, Batman
 - Alex Moffat, comedian, Saturday Night Live
 - D. W. Moffett, actor, Switched at Birth, For Your Love, Friday Night Lights
 - Nazr Mohammed, center for eight NBA teams
 - Kid Mohler, baseball player, Pacific Coast League Hall of Fame
 - Laszlo Moholy-Nagy, artist, founder of IIT Institute of Design (born in Hungary)
 - John Moisant, early 20th Century aviator
 - Bo Molenda, NFL player and coach
 - Jim Molinari, basketball head coach at Western Illinois, Bradley, Northern Illinois and Minnesota
 - David Molk, NFL center 2012-15
 - Jeff Monken, football coach, Army
 - Harriet Monroe, poet
 - Meredith Monroe, actress, Dawson's Creek, Criminal Minds
 - Zach Monroe, pitcher for 1958 World Series champion New York Yankees
 - Eric Monte, creator of TV series Good Times
 - Kahmari Montgomery, sprinter
 - Karen Montgomery, actress, producer
 - Dwight L. Moody, evangelical minister, publisher, established Moody Bible Institute (born in Massachusetts)
 - William Vaughn Moody, dramatist and poet (born in Indiana)
 - Thomas Mooney, imprisoned labor leader
 - Allen F. Moore, U.S. Representative 1921–25
 - Annabelle Moore, dancer, silent film actress
 - Ben Moore, player in Israeli Basketball Premier League
 - Charles R. Moore, actor
 - Christina Moore, actress, Hawthorne, Hyperion Bay, Hot Properties
 - Clayton Moore, actor, The Lone Ranger
 - Dayton Moore, baseball executive (born in Kansas)
 - D. J. Moore, NFL defensive back 2009–14
 - Dolores Moore, pro baseball player
 - Eleanor Moore, pro baseball player
 - Graham Moore, Oscar-winning screenwriter, The Imitation Game
 - Irving J. Moore, television director
 - Jesse Hale Moore, Civil War general, U.S. Representative
 - John Moore, NHL defenseman
 - John Moore, lieutenant governor 1842–46, Mexican–American War officer (born in England)
 - Margo Moore, actress, fashion model
 - Richard Moore, cinematographer, co-creator of Panavision
 - Stephen Moore, economic writer, policy analyst
 - Tim Moore, actor and comedian, Amos 'n' Andy
 - Emery Moorehead, tight end for Super Bowl XX champion Chicago Bears
 - Dick Moores, cartoonist
 - Pablo Morales, swimmer, 1984 and 1992 Olympic golds, Nebraska coach
 - Bugs Moran, gangster, rival of Al Capone
 - Jackie Moran, actor, The Adventures of Tom Sawyer, Buck Rogers
 - Jim Moran, automobile mogul, philanthropist
 - Lee Moran, actor, film director, screenwriter
 - Polly Moran, actress, Caught Short, Alice in Wonderland
 - Terry Moran, correspondent for ABC News
 - Tom Morello, guitarist for Rage Against the Machine
 - Anna Morgan, drama teacher (born in New York)
 - Cindy Morgan, actress, Caddyshack, Tron
 - Ed Morgan, infielder for Cleveland Indians 1928–33
 - Helen Morgan, singer, portrayed in biopic The Helen Morgan Story
 - Read Morgan, actor, The Deputy
 - Trevor Morgan, actor, The Sixth Sense, Jurassic Park III, The Patriot
 - Big Bill Morganfield, blues singer and guitarist
 - George Moriarty, MLB player, manager and umpire
 - Audrey Morris, jazz singer
 - Buckner Stith Morris, Mayor of Chicago 1838–39 (born in Kentucky)
 - Johnny Morris, receiver for Chicago Bears, sportscaster (born in California)
 - Lamorne Morris, actor, New Girl
 - Max Morris, basketball and football All-American for Northwestern
 - Allie Morrison, freestyle wrestler, 1928 Olympic gold medalist (born in Iowa)
 - David Morrison, astrophysicist
 - James L. D. Morrison, Mexican War officer, U.S. Representative 1856–57
 - Jennifer Morrison, actress, model, House, How I Met Your Mother, Star Trek, Once Upon a Time
 - Karen Morrison-Comstock, 1974 Miss USA
 - William Ralls Morrison, Civil War officer, U.S. Representative
 - Byron Morrow, actor, Executive Suite
 - Karen Morrow, singer
 - William Morrow, screenwriter
 - Lee Mortimer, journalist and author
 - Amy Morton, actress, Up in the Air, Chicago P.D.
 - Charles Morton, actor
 - Jelly Roll Morton, jazz pianist (born in Louisiana)
 - Joy Morton, founder of Morton Salt company and Morton Arboretum
 - Lorraine H. Morton, first African-American mayor of Evanston
 - John Mosca, restaurateur in Louisiana
 - Margaret Moser, music journalist
 - Porter Moser, basketball coach, Illinois State, Loyola, Oklahoma
 - Beth Moses, commercial astronaut
 - Mark Moses, actor, Desperate Housewives, Grand, Mad Men
 - Senta Moses, actress, General Hospital, Running the Halls, Home Alone
 - Peter Moskos, assistant professor at John Jay College of Criminal Justice
 - Stewart Moss, actor, writer and director
 - Burton C. Mossman, cattleman and lawman
 - Johnny Mostil, outfielder for White Sox, two-time AL stolen-base leader
 - Willard Motley, columnist and author
 - Ben Roy Mottelson, physicist, 1975 Nobel Prize
 - Markos Moulitsas, founder of liberal blog Daily Kos, columnist
 - Samuel W. Moulton, lawyer, U.S. Representative (born in Massachusetts)
 - Anson Mount, actor, Hell on Wheels, Non-Stop, Star Trek: Strange New Worlds
 - Edgar Ansel Mowrer, foreign correspondent and author
 - Paul Scott Mowrer, war correspondent and editor
 - John Moyer, lineman for arena football's Chicago Rush
 - Mr. T, actor, Rocky III, The A-Team
 
Mu–Mz
- Jerry Muckensturm, linebacker for Chicago Bears 1976–83
 - Jessie Mueller, singer and actress, Tony Award winner
 - Earl Muetterties, inorganic chemist
 - Jabir Herbert Muhammad, Nation of Islam official, manager of Muhammad Ali (born in Michigan)
 - Gavin Muir, actor
 - John Mulaney, stand-up comedian, Saturday Night Live writer, producer, host
 - Mark Mulder, pitcher for Oakland Athletics and St. Louis Cardinals
 - Clarence E. Mulford, creator of Hopalong Cassidy
 - David Mulford, U.S. Ambassador to India 2004–09
 - Martin Mull, actor, Fernwood 2 Night, Mr. Mom, Clue, Serial, Roseanne, Dads
 - Vern Mullen, NFL halfback 1923–27
 - Bill Mulliken, swimming gold medalist, 1960 Olympics
 - Bryan Mullins, basketball player and head coach for Southern Illinois
 - George Mundelein, cardinal and Archbishop of Chicago (born in New York)
 - Madman Muntz, car-stereo pioneer
 - Edgar Munzel, baseball writer
 - Ira Murchison, sprinter, 1956 Summer Olympics relay gold
 - Ben Murphy, actor, Alias Smith and Jones, Winds of War (born in Arkansas)
 - Charles Murphy, owner of Chicago Cubs 1906–13
 - David Lee Murphy, country music artist
 - Dick Murphy, mayor of San Diego 2000–05
 - John Murphy, swimmer, gold medalist at 1972 Summer Olympics
 - John Benjamin Murphy, surgeon and innovator (born in Wisconsin)
 - Kelly Murphy, volleyball player
 - Thomas Joseph Murphy, archbishop of Seattle 1990–97
 - Bill Murray, comedian and Oscar-nominated actor, Saturday Night Live, the Ghostbusters movies, Stripes, Tootsie, Caddyshack, Groundhog Day, Scrooged, Lost in Translation, St. Vincent
 - Brian Doyle-Murray, actor, voice artist, Saturday Night Live, Marvelous Misadventures of Flapjack, The Razor's Edge, Wayne's World
 - Elizabeth Murray, artist
 - Joel Murray, actor, Dharma & Greg, Love & War, Grand, Mad Men
 - John Murray, music teacher, founder of Naperville, Illinois
 - Brent Musburger, sportscaster, Northwestern alumnus, 1960s Chicago sportswriter (born in Oregon)
 - Todd Musburger, talent agent
 - John Musker, animation director, Aladdin, Hercules, The Princess and the Frog
 - George Musso, Hall of Fame lineman for Chicago Bears
 - Max Mutchnick, TV producer, creator of Will & Grace
 - Riccardo Muti, Chicago symphony conductor 2008-23 (born in Italy)
 - Mike Myers, MLB pitcher 1995–2007
 - Don Myrick, saxophonist for Earth, Wind & Fire, Phil Collins
 
N
Na–Nn
- John Naber, swimmer, winner of five Olympic medals
 - Bill Nack, author and journalist
 - Abdel Nader, forward, Northern Illinois and NBA (born in Egypt)
 - Steven R. Nagel, astronaut
 - Jack Nagle, basketball coach for Marquette 1953–58
 - Ajay Naidu, actor, Office Space, LateLine
 - Suzy Nakamura, actress, The 40-Year-Old Virgin, Dr. Ken
 - Duke Nalon, auto racer in Motorsports Hall of Fame of America
 - Bryan Namoff, pro soccer player (born in Nevada)
 - Albinus Nance, Governor of Nebraska 1879–1883
 - Ray Nance, trumpeter
 - Joseph Naper, shipbuilder, first village president of Naperville
 - Robert Nardelli, CEO, Chrysler, Home Depot (born in Pennsylvania)
 - Charles W. Nash, automobile entrepreneur, created Nash Motors
 - Heather Nauert, anchor for Fox News Channel
 - Tom Neal, actor, Detour, Crime, Inc.
 - Long John Nebel, radio personality
 - Oscar Neebe, convicted Haymarket affair anarchist (born in New York)
 - Carrie Neely, four-time U.S. Open tennis doubles champion
 - Cal Neeman, MLB catcher 1957–63
 - John G. Neihardt, author and historian
 - A.L. Neiman, co-founder of Neiman Marcus
 - Bernie Neis, MLB player 1920–27
 - Baby Face Nelson, bank robber and murderer in 1930s
 - Battling Nelson, boxer, lightweight champion 1905–06 (born in Denmark)
 - John Nelson, swimmer, 1964 and 1968 Olympic medalist
 - Karl Nelson, lineman for Super Bowl XXI champion New York Giants
 - Michael J. Nelson, comedian and writer, Mystery Science Theater 3000
 - Wayne Nelson, musician from classic rock's Little River Band
 - Eliot Ness, treasury agent, chief investigator of Prohibition Bureau, subject of film and TV series The Untouchables
 - Dawn Clark Netsch, state senator, comptroller, gubernatorial candidate
 - Lois Nettleton, 1948 Miss Illinois, Emmy-winning actress, The Twilight Zone, Come Fly with Me, Period of Adjustment
 - Jerry Neudecker, baseball umpire
 - Harry Neumann, cinematographer
 - P. Scott Neville Jr., judge, Supreme Court of Illinois
 - Allan Nevins, historian and 1933 Pulitzer Prize-winning biographer
 - Arthur S. Nevins, U.S. Army general, friend of Dwight Eisenhower
 - Walter C. Newberry, Civil War officer, Chicago postmaster, U.S. Representative (born in New York)
 - New Colony Six, rock band from Chicago
 - Francis K. Newcomer, general, Panama Canal Zone governor 1948–52
 - Bob Newhart, Emmy and Grammy-winning comedian, actor, The Bob Newhart Show, Newhart, Catch-22, In & Out, Elf
 - Joe Newton, cross country coach, 28 state championships
 - Kim Ng, MLB executive (born in Indiana)
 - Alberta Nichols, songwriter
 - Marisol Nichols, actress, Riverdale, Resurrection Blvd., 24, Blind Justice
 - Mike Nichols, Oscar and Tony-winning film and stage director, alumnus of University of Chicago and Second City (born in Russia)
 - Nichelle Nichols, actress, Nyota Uhura on Star Trek
 - Danell Nicholson, heavyweight boxer
 - Seth Barnes Nicholson, astronomer
 - Carl Nicks, NBA guard 1980–83, played for 1979 NCAA runner-up Indiana State
 - John George Nicolay, secretary to Abe Lincoln (born in Germany)
 - Arthur Nielsen, founder of Nielsen Company, television ratings
 - Rick Nielsen, musician, Cheap Trick
 - Ben Niemann, NFL linebacker, Super Bowl LIV champion Kansas City Chiefs (born in Iowa)
 - Audrey Niffenegger, author, The Time Traveler's Wife
 - Alexa Nikolas, actress, Zoey 101, Hidden Hills
 - Rob Ninkovich, NFL linebacker 2006-16, two-time Super Bowl champion with New England Patriots
 - Ray Nitschke, Hall of Fame linebacker for Green Bay Packers, five-time NFL champion
 - Frank Nitti, gangster, associate of Al Capone (born in Italy)
 - Jack Nitzsche, Oscar-winning songwriter, "Up Where We Belong"
 - Agnes Nixon, creator of All My Children
 - Ogonna Nnamani, volleyball player, two-time Olympian
 
No–Nz
- Natalia Nogulich, actress, Star Trek: The Next Generation
 - Christopher Nolan, director, Batman Begins, The Dark Knight, Oppenheimer (born in England)
 - Jonathan Nolan, screenwriter, The Dark Knight Rises, Interstellar, Westworld (born in England)
 - George Nolfi, screenwriter, The Bourne Ultimatum, Ocean's Twelve
 - Ken Nordine, voice-over artist (born in Iowa)
 - Nelson Norgren, four-sport athlete, 34-year University of Chicago coach
 - Ken Norman, player for three NBA teams
 - Bruce Norris, owner of NHL's Detroit Red Wings 1952–82
 - James D. Norris, chairman of Chicago Blackhawks, member of Hockey Hall of Fame
 - James E. Norris, miller, part-owner of Chicago Stadium and NHL teams (born in Canada)
 - Frank Norris, novelist
 - Lou North, MLB pitcher 1913–24
 - Cliff Norton, actor
 - Ken Norton, heavyweight boxer and actor, Mandingo
 - Ken Norton Jr., NFL linebacker and coach
 - Red Norvo, xylophone and vibraphone musician
 - Kim Novak, Golden Globe-winning actress, Vertigo, Picnic, Pal Joey, Bell, Book and Candle, Kiss Me, Stupid
 - Larry Novak, musical director at Mister Kelly's
 - Robert Novak, syndicated columnist, TV personality, author, conservative political commentator
 - Steve Novak, NBA forward 2006-17
 - Jay Novello, actor
 - Brent Novoselsky, tight end for Minnesota Vikings 1988–94
 - Christopher Nowinski, author, former WWE professional wrestler
 - Ted Nugent, rock musician (born in Michigan)
 - Kendrick Nunn, NBA guard
 - Mike Nussbaum, actor, Men in Black, Things Change
 - Russell Nype, Broadway actor and Tony Award winner
 - David Nyvall, theologian, first president of North Park University (born in Sweden)
 
O
Oa–Ok
- Barack Obama, 44th President of the United States; former US Senator from Illinois (2004–2008) (born in Hawaii)
 - Michelle Obama, attorney, author, First Lady of the United States 2009-17, wife of Barack Obama
 - Dean O'Banion, organized crime figure
 - Ken Oberkfell, MLB infielder 1977–92, played for 1982 World Series champion St. Louis Cardinals
 - Jim Oberweis, dairy owner, politician
 - Arch Oboler, playwright, radio personality, film director
 - Ed O'Bradovich, defensive end for 1963 NFL champion Chicago Bears
 - Hugh O'Brian, actor, The Life and Legend of Wyatt Earp, Ten Little Indians, Come Fly With Me, The Shootist
 - Chris O'Brien, pro football pioneer, owner of Chicago Cardinals
 - George M. O'Brien, U.S. Representative 1973–86
 - Mary K. O'Brien, judge
 - Thomas J. O'Brien, 24-year U.S. Representative
 - Jack O'Callahan, hockey player for Chicago Blackhawks and in 1980 "Miracle on Ice" game
 - Bob Ociepka, basketball coach
 - Mike O'Connell, NHL player and executive
 - Tommy O'Connell, quarterback, Cleveland Browns, 1957 NFL title game
 - Colleen O'Connor, ice dancer, three-time U.S. champion, Olympic bronze
 - Donald O'Connor, dancer, singer, actor, Singin' in the Rain, There's No Business Like Show Business, Francis
 - Kevin J. O'Connor, actor, Color of Night, The Mummy, There Will Be Blood
 - Leslie O'Connor, baseball executive
 - Tim O'Connor, actor, Peyton Place, Buck Rogers in the 25th Century
 - Tommy O'Connor, gangster (born in Ireland)
 - Anita O'Day, singer
 - Hank O'Day, Baseball Hall of Fame umpire
 - Rasmea Odeh, convicted of immigration fraud, imprisoned for terrorist bombing
 - Bill Odenkirk, comedy writer, actor, producer, Mr. Show, The Simpsons
 - Bob Odenkirk, actor, comedian, writer, director, Better Call Saul, Breaking Bad, Nebraska, Mr. Show, Fargo
 - Chris O'Donnell, actor, NCIS: Los Angeles, Scent of a Woman, Batman Forever, Batman & Robin
 - Jake Odorizzi, MLB pitcher
 - Matt O'Dwyer, NFL offensive lineman 1995–2004
 - Joe Oeschger, MLB pitcher 1915–24
 - Bob O'Farrell, catcher for three MLB teams, 1926 MVP and World Series champion, manager
 - Nick Offerman, actor, comedian, Parks and Recreation, The Lego Movie, We're the Millers, Fargo
 - William Butler Ogden, politician (Democrat), businessman, first Mayor of Chicago (born in New York)
 - Joseph Ogle, Revolutionary War soldier, established state's first Methodist church (born in Maryland)
 - Richard James Oglesby, politician (Republican), Civil War officer, U.S. Senator, three-time Governor of Illinois (born in Kentucky)
 - Richard B. Ogilvie, lawyer, Cook County Sheriff 1962-66, Governor of Illinois 1969–73 (born in Missouri)
 - Gail O'Grady, actress, American Dreams, NYPD Blue, Hellcats
 - David Ogrin, pro golfer
 - Tom O'Halleran, U.S. Representative in Arizona
 - Barratt O'Hara, lieutenant governor, U.S. Representative 1949–69
 - Janice O'Hara, pro baseball player
 - Edward J. O'Hare, lawyer, associate of Al Capone, father of war hero Butch O'Hare (for whom O'Hare Airport was named)
 - Michael O'Hare, actor, Babylon 5
 - Don Ohl, five-time All-Star for three NBA teams
 - Don Ohlmeyer, Emmy and Peabody Award-winning television producer, Monday Night Football, Saturday Night Live
 - Jahlil Okafor, basketball player for Duke and Philadelphia 76ers, third pick of 2015 NBA draft
 - Georgia O'Keeffe, artist, Art Institute of Chicago student (born in Wisconsin)
 
Ol–Oz
- Douglas R. Oberhelman, CEO of Caterpillar Inc.
 - Porsha Olayiwola, Boston poet laureate
 - Ed Olczyk, player for six NHL teams, coach, TV commentator
 - Arne Oldberg, composer, Northwestern professor
 - Claes Oldenburg, sculptor (born in Sweden)
 - Brian Oldfield, shot putter
 - Jawann Oldham, center for eight NBA teams
 - Catherine O'Leary, said to be indirectly responsible for Great Chicago Fire
 - Charley O'Leary, oldest MLB player (58) ever to bat
 - Matt O'Leary, actor
 - John M. Olin, owner of 1974 Kentucky Derby winner Cannonade
 - Ken Olin, actor, director, producer, Thirtysomething, Brothers & Sisters
 - Gene Oliver, catcher for five MLB teams
 - Guy Oliver, silent-film actor
 - King Oliver, jazz musician (born in Louisiana)
 - Martha Capps Oliver, poet, hymnwriter
 - Gertrude Olmstead, silent-film actress
 - James Olson, actor, The Andromeda Strain, Rachel, Rachel, Ragtime
 - Francis O'Neill, Chicago chief of police 1901–05 (born in Ireland)
 - Kyle Onstott, author, Mandingo
 - Jerry Orbach, film, TV and Tony-winning stage actor, Law & Order, Prince of the City, Dirty Dancing, Beauty and the Beast
 - Dick Orkin, radio personality
 - Suze Orman, author, financial advisor, television commentator
 - Red Ormsby, Major League Baseball umpire 1923–41
 - Carey Orr, cartoonist
 - David Orr, alderman, Cook County clerk, briefly Mayor of Chicago
 - Johnny Orr, basketball coach, Michigan and Iowa State
 - Warren H. Orr, judge (born in Missouri)
 - Zak Orth, actor, Revolution
 - Kid Ory, musician and bandleader (born in Louisiana)
 - Harold Osborn, gold medalist in decathlon and high jump at 1924 Summer Olympics
 - Dan Osinski, MLB pitcher 1962–70
 - Wally Osterkorn, pro basketball player
 - Fritz Ostermueller, MLB pitcher 1934–48
 - Johnny Ostrowski, MLB player for Cubs and White Sox
 - Jim O'Toole, MLB pitcher 1958–67
 - Dave Otto, MLB pitcher 1987-94, sportscaster
 - Diana Oughton, student activist, member of The Weathermen
 - Antoine Ouilmette, early settler, Wilmette namesake (born in Canada)
 - Harold Ousley, jazz musician
 - David K. Overstreet, judge
 - Michael Ovitz, co-founder of Creative Artists Agency, president of Walt Disney Company 1995–97
 - Ruth Bryan Owen, first female in Florida elected to U.S. Congress; ambassador to Denmark and Iceland
 - Brick Owens, MLB umpire 1908–37 (born in Wisconsin)
 - Mel Owens, NFL linebacker 1981-89 (born in Michigan)
 - Joseph W. Ozbourn, decorated World War II soldier
 - Marite Ozers, 1963 Miss USA (born in Latvia)
 - Ray Ozzie, executive with Microsoft, Hewlett-Packard
 
P
Pa–Pd
- Cliff Padgett, motorboat builder, hydroplane racer
 - Walter Paepcke, philanthropist, founder of Aspen Institute
 - Geraldine Page, Oscar-winning actress, The Trip to Bountiful, Hondo, Sweet Bird of Youth (born in Missouri)
 - Harlan Page, two-sport star for University of Chicago, head coach of Butler basketball, Indiana football
 - Kimberly Page, professional wrestling personality
 - Ruth Page, ballerina, Chicago patron of the arts (born in Indiana)
 - Jean Paige, silent-film actress
 - Eleazar A. Paine, lawyer, controversial Civil War officer (born in Ohio)
 - Norman C. Paine, football coach, Baylor, Arkansas and Iowa State
 - Curtis Painter, NFL quarterback 2009–14
 - Ho-Sung Pak, actor, martial artist, action choreographer
 - Max Palevsky, philanthropist, computer technology pioneer
 - William S. Paley, broadcasting pioneer, chief executive of CBS
 - Donn Pall, MLB pitcher 1988–98
 - Ashley Palmer, actress, singer, Paranormal Activity
 - Bee Palmer, singer, "Please Don't Talk About Me When I'm Gone"
 - Bertha Palmer, philanthropist (born in Kentucky)
 - Betsy Palmer, actress and TV personality, Mister Roberts, The Tin Star, I've Got a Secret, Friday the 13th (born in Indiana)
 - John M. Palmer, politician (Democrat, Republican, Free Soil), Civil War general, U.S. Senator 1891–97, Governor of Illinois 1869–73 (born in Kentucky)
 - John McAuley Palmer, World War II general
 - Keke Palmer, actress, singer, Madea's Family Reunion, Joyful Noise, Hustlers, Nope
 - Peter Palmer, singer, athlete, actor, Li'l Abner (born in Wisconsin)
 - Phoebe Palmer, evangelist and author (born in New York)
 - Potter Palmer, land developer, Palmer House founder (born in New York)
 - Shirley Palmer, actress
 - Danielle Panabaker, actress, Shark, Empire Falls, Friday the 13th, The Flash (born in Georgia)
 - Kay Panabaker, actress, Summerland, Phil of the Future (born in Texas)
 - Norman Panama, screenwriter, director, White Christmas, Road to Utopia, Mr. Blandings Builds His Dream House
 - Ken Panfil, NFL lineman 1956–62
 - James Pankow, musician, a founding member of rock band Chicago (born in Missouri)
 - John Pankow, actor, To Live and Die in L.A., A Stranger Among Us, Episodes (born in Missouri)
 - Chuck Panozzo, bass player for rock band Styx
 - John Panozzo, drummer for rock band Styx
 - Al Papai, MLB pitcher 1948–55
 - Billy Papke, middleweight boxing champion, Hall of Fame
 - Erik Pappas, MLB catcher
 - Milt Pappas, MLB pitcher 1957-73, no-hitter for Chicago Cubs, managed Chicago Storm (born in Michigan)
 - Walter Parazaider, musician with band Chicago
 - Jimmy Pardo, comedian, actor
 - Sara Paretsky, crime novelist (born in Iowa)
 - Jannero Pargo, guard for six NBA teams
 - Tiny Parham, pianist and bandleader (born in Canada)
 - Jane Park, LPGA golfer
 - Anthony Parker, guard for four NBA teams, 2004 Israeli Basketball Premier League MVP, executive with Orlando Magic
 - Candace Parker, two-time NCAA champion, two-time Olympic gold medalist, two-time WNBA champion and MVP
 - Eric Parker, wide receiver for San Diego Chargers 2002–07
 - Francis W. Parker, education reformer (born in New Hampshire)
 - Jabari Parker, basketball forward, four-time state champion with Simeon, second pick of 2014 NBA draft
 - Salty Parker, MLB player, coach, manager
 - Sonny Parker, guard for Golden State Warriors 1976–82
 - Wes Parker, first baseman for Los Angeles Dodgers 1964–72
 - Larry Parks, Oscar-nominated actor, The Jolson Story, Down to Earth, Jolson Sings Again, The Swordsman
 - Ben Parr, journalist, author, venture capitalist
 - Vernon Parrington, historian, 1928 Pulitzer Prize
 - Terell Parks, player in Israeli Basketball Premier League
 - Albert Parsons, editor, anarchist executed after Haymarket affair (born in Alabama)
 - Claude V. Parsons, educator, U.S. Representative 1930–41
 - Louella Parsons, syndicated newspaper columnist
 - Lucy Parsons, anarchist and labor organizer (born in Texas)
 - Cecil A. Partee, president of state senate (born in Arkansas)
 - Ed Paschke, artist
 - Tony Pashos, NFL offensive tackle 2003–13
 - Geeta Patel, director and screenwriter
 - Ravi Patel, actor, Grandfathered
 - Don Patinkin, Israeli-American economist, President of Hebrew University of Jerusalem
 - Mandy Patinkin, actor and singer, The Princess Bride, Dick Tracy, Ragtime, Yentl, Chicago Hope, Homeland
 - Sheldon Patinkin, theater director for Columbia College, Second City
 - Danica Patrick, auto racer, best finish of any woman in Daytona 500, Indianapolis 500 (born in Wisconsin)
 - David Patrick, Olympic hurdler
 - Deval Patrick, governor of Massachusetts 2007–15
 - Laurdine Patrick, saxophonist
 - Leonard Patrick, organized crime figure (born in England)
 - Stan Patrick, pro basketball player
 - Alexandra Patsavas, TV/film music supervisor, Grey's Anatomy, Supernatural, The Hunger Games: Catching Fire
 - Lauren Patten, singer and actress, Tony Award winner
 - Alicia Patterson, editor and publisher, founder of Newsday
 - Cissy Patterson, editor and publisher, countess
 - Don Patterson, producer, animator, director, The Smurfs, Dumbo, Pinocchio, Fantasia
 - Joseph Medill Patterson, editor, publisher, New York Daily News founder
 - Pat Patterson, MLB player, New York Giants 1921
 - Marty Pattin, pitcher for five MLB teams
 - Spencer Patton, MLB relief pitcher
 - Art Paul, graphic artist for Playboy 1953–83; designer of bunny logo
 - Josh Paul, catcher for four MLB teams
 - Gene Paulette, MLB infielder 1914–20
 - Henry Paulson, financier, 2006–09 U.S. Secretary of the Treasury (born in Florida)
 - Pawnee Bill, Wild West showman with Buffalo Bill
 - John Paxson, three-time NBA champion, executive for Chicago Bulls (born in Ohio)
 - Melanie Paxson, actress
 - Tom Paxton, folk musician and singer-songwriter, 2009 Grammy Lifetime Achievement Award
 - Ethel L. Payne, journalist, activist
 - John B. Payne, Secretary of Interior 1920–21 (born in West Virginia)
 - Sally Payne, actress
 - William Morton Payne, educator, writer (born in Massachusetts)
 - Christian Payton, actor, The Temptations
 - Sean Payton, head coach of Denver Broncos and Super Bowl XLIV champion New Orleans Saints (born in California)
 - Jarrett Payton, pro football player, radio personality
 - Walter Payton, Hall of Fame running back for Super Bowl XX champion Chicago Bears (born in Mississippi)
 
Pe–Pg
- Walter C. Peacock, jeweler, Lincoln Park Gun Club founder
 - Barry Pearson, NFL wide receiver 1972–76
 - Drew Pearson, syndicated newspaper columnist
 - Paul Martin Pearson, professor, governor of Virgin Islands
 - Preston Pearson, running back for three NFL teams
 - Todd Peat, NFL offensive lineman 1987–93
 - Donald C. Peattie, author and botanist
 - Elia W. Peattie, journalist and naturalist (born in Michigan)
 - John Mason Peck, Baptist minister and author (born in Connecticut)
 - Ferdinand Peck, philanthropist, financier of Auditorium Building, Chicago
 - George Peek, economist
 - Westbrook Pegler, journalist, 1941 Pulitzer Prize (born in Minnesota)
 - Chris Pelekoudas, MLB umpire
 - Rob Pelinka, general manager of Los Angeles Lakers, player for three Final Four basketball teams
 - Clara Peller, commercial actress, "Where's the beef?"
 - Michael Peña, actor, World Trade Center, Crash, Shooter, End of Watch, American Hustle, The Martian
 - D. A. Pennebaker, documentary filmmaker, Dont Look Back, The War Room, Unlocking the Cage
 - Jack Perconte, infielder for four MLB teams
 - Chuck Percy, president of Bell & Howell Corporation, U.S. Senator (Republican) of Illinois for 20 years (born in Florida)
 - George Periolat, silent-film actor
 - Dewayne Perkins, comedian and screenwriter
 - Marlin Perkins, host of television's Wild Kingdom, 18-year director of Lincoln Park Zoo (born in Missouri)
 - Walter Perkins, drummer
 - Edythe Perlick, pro baseball player
 - Bill Perry, cartoonist
 - Felton Perry, actor, Magnum Force, RoboCop
 - Jeff Perry, actor, Nash Bridges, Grey's Anatomy, Scandal
 - Pat Perry, MLB pitcher 1985-90
 - Zoe Perry, actress, Young Sheldon
 - Rudy Perz, advertising executive, creator of Pillsbury Doughboy
 - Jim Peterik, singer-songwriter with bands The Ides of March and Survivor, co-wrote "Eye of the Tiger"
 - Elizabeth Peters, mystery novelist
 - Joan Peters, journalist and author
 - Ted Petersen, offensive lineman for two-time Super Bowl champion Pittsburgh Steelers
 - William Petersen, actor, Gil Grissom on CSI, Manhunter, To Live and Die in L.A., The Rat Pack
 - Dan Peterson, pro basketball coach
 - Drew Peterson, police officer, convicted murderer
 - Fritz Peterson, pitcher for New York Yankees and Cleveland Indians
 - Pehr August Peterson, Rockford, Illinois industrialist and philanthropist
 - Peter George Peterson, CEO of Lehman Bros., Bell & Howell, 1972–73 U.S. Secretary of Commerce (born in Nebraska)
 - Bernice Petkere, songwriter
 - Robert Petkoff, stage actor (born in California)
 - Harry Mark Petrakis, author (born in Missouri)
 - Lloyd Pettit, hockey sportscaster
 - George Petty, pinup artist (born in Louisiana)
 - Dave Peyton, songwriter and musician
 - Jeff Pfeffer, MLB pitcher 1911–24
 - Wally Pfister, Oscar-winning cinematographer
 - Father Michael Pfleger, controversial Roman Catholic priest
 - Lee Pfund, pitcher for Brooklyn Dodgers
 - Randy Pfund, head coach for Los Angeles Lakers 1992–94, general manager for Miami Heat
 
Ph–Pn
- Liz Phair, singer and songwriter (born in Connecticut)
 - Roger Phegley, guard for five NBA teams
 - Art Phelan, MLB player for Cincinnati Reds and Chicago Cubs
 - Mary Philbin, silent-film actress, Phantom of the Opera
 - Andy Phillip, Hall of Fame basketball player for Illinois
 - Busy Philipps, actress, Dawson's Creek, Freaks and Geeks, ER
 - Emo Philips, entertainer and comedian
 - Irna Phillips, creator of Guiding Light and As the World Turns
 - John Calhoun Phillips, Governor of Arizona 1929–31
 - Julianne Phillips, model, actress, first wife of Bruce Springsteen
 - Kyra Phillips, television journalist
 - Wally Phillips, radio personality (born in Ohio)
 - William Phipps, actor, Cinderella (born in Indiana)
 - Brian Piccolo, running back for Chicago Bears, subject of Brian's Song (born in Massachusetts)
 - Bob Pickens, Olympic wrestler and Bears offensive lineman
 - Ollie Pickering, first batter in MLB American League history
 - William Pickering, 19th Century governor of Washington (born in England)
 - Pat Pieper, public-address announcer at Wrigley Field for 59 years
 - Alec Pierce, NFL wide receiver
 - Billy Pierce, pitcher, scout, broadcaster for Chicago White Sox, seven-time All-Star (born in Michigan)
 - George Pierce, MLB player 1912–17
 - Walter M. Pierce, 17th Governor of Oregon
 - Jimmy Piersall, baseball player and Chicago sportscaster, subject of Fear Strikes Out (born in Connecticut)
 - Geoff Pierson, actor, Unhappily Ever After, 24, Dexter
 - Pete Pihos, decorated soldier, six-time Pro Bowl player for NFL's Philadelphia Eagles 1947–55 (born in Florida)
 - Janet Pilgrim, model, three-time Playboy centerfold
 - Andy Pilney, football coach, Tulane 1954–61 (born in Kansas)
 - Steve Pink, writer, director, Accepted, Hot Tub Time Machine
 - Allan Pinkerton, detective, founder of Pinkerton's agency
 - Tonya Pinkins, Tony Award-winning actress, Jelly's Last Jam, Fading Gigolo, All My Children
 - Maria Pinto, fashion designer
 - Wally Pipp, first baseman for Detroit Tigers and 1923 World Series champion New York Yankees
 - Scottie Pippen, Hall of Fame forward for Chicago Bulls six-time champions (born in Arkansas)
 - Louis Piquett, lawyer of John Dillinger
 - Pauline Pirok, pro baseball player
 - Skip Pitlock, MLB pitcher 1970–75
 - Arthur Pitney, inventor of postage meter, co-founder of Pitney Bowes
 - Jeremy Piven, Emmy-winning actor, Entourage, Mr. Selfridge, Very Bad Things, Old School
 - Plain White T's, rock band from Chicago
 - Polly Platt, film producer, screenwriter
 - James E. Plew, aviation pioneer
 - Pete Ploszek, actor, Teen Wolf, the Teenage Mutant Ninja Turtles films
 - Ed Plumb, composer for Disney films, Fantasia, Bambi
 
Po–Pz
- John Podesta, White House Chief of Staff under Bill Clinton
 - Amy Poehler, comedian, actress, Second City, Saturday Night Live, Parks and Recreation (born in Massachusetts)
 - Angelo Poffo, professional wrestler
 - Tasha Pointer, basketball coach, UIC
 - D. A. Points, professional golfer
 - Matthew Polenzani, opera singer
 - Ben Pollack, big-band era bandleader
 - Fritz Pollard, first African-American head coach in NFL and Pro Football Hall of Famer
 - Dan Ponce, radio-TV journalist, singer with Straight No Chaser
 - Phil Ponce, Chicago television personality
 - Irving Kane Pond, architect (born in Michigan)
 - Cappie Pondexter, pro basketball player, 2007 MVP of WNBA Finals (born in California)
 - Ernest Poole, Pulitzer Prize-winning novelist
 - William Frederick Poole, first Chicago Public Library librarian, designed Newberry Library (born in Massachusetts)
 - Carmelita Pope, actress
 - Nathaniel Pope, politician and advocate of statehood (born in Kentucky)
 - John Porter, U.S. Representative 1980–2001
 - H.V. Porter, coach, coined term "March Madness"
 - Kevin Porter, guard for three NBA teams, four-time league assist leader
 - Glenn Poshard, U.S. Representative, Southern Illinois University president
 - Michael Posner, attorney, human rights advocate, Assistant Secretary of State under Barack Obama
 - C. W. Post, breakfast cereal mogul
 - Marjorie Merriweather Post, founder of General Foods
 - Philip S. Post, Civil War general, U.S. Representative (born in New York)
 - Lou Pote, MLB pitcher 1999–2004
 - Nels Potter, pitcher for six MLB teams
 - Leah Poulos-Mueller, speed skater, 1976 and 1980 Olympic medalist
 - Jordyn Poulter, volleyball gold medalist, 2020 Summer Olympics
 - Edward B. Powell, film composer
 - Jack Powell, MLB pitcher, won 245 games
 - John Wesley Powell, explorer, Civil War officer, Illinois Wesleyan professor (born in New York)
 - Maud Powell, violinist
 - Paul Powell, controversial politician
 - Roger Powell, Illinois basketball player, Valparaiso head coach
 - Jenny Powers, actress and 2000 Miss Illinois
 - John A. "Shorty" Powers, NASA official, voice of Mercury Control (born in Ohio)
 - Richard Powers, author, 2019 Pulitzer Prize
 - John Powless, basketball head coach for Wisconsin 1968-76
 - A. George Pradel, mayor of Naperville 1995–2015
 - Deborah Pratt, actress, writer
 - Toni Preckwinkle, teacher, president of Cook County Board
 - Tom Preissing, NHL defenseman
 - Mike Prendergast, MLB pitcher 1914–19
 - Patrick Prendergast, assassin of Chicago mayor, 1893 (born in Ireland)
 - Gary Pressy, organist at Wrigley Field 1987-2019
 - Keith Preston, writer
 - Louis Price, singer with Temptations, Drifters
 - Melvin Price, 33-year U.S. Representative
 - Julian Priester, trombonist
 - George W. Prince, eight-term U.S. Representative
 - Tom Prince, MLB catcher 1987–2003
 - Joe Principe, musician, member of band Rise Against
 - John Prine, singer-songwriter, 2020 Grammy Lifetime Achievement Award
 - Bret Prinz, MLB pitcher 2001–07
 - Mike Prior, defensive back for Super Bowl XXXI champion Green Bay Packers
 - A.N. Pritzker, lawyer and philanthropist (born in Russia)
 - Donald Pritzker, co-founder and president of Hyatt hotels
 - Jay Pritzker, co-founder, Hyatt Hotel chain
 - J. B. Pritzker, principal owner of Hyatt, philanthropist, 43rd Governor of Illinois
 - Penny Pritzker, U.S. Secretary of Commerce 2013-17
 - Robert Pritzker, president of Marmon Group
 - Cory Provus, baseball broadcaster
 - William Proxmire, 42-year U.S. Senator of Wisconsin
 - Richard Pryor, Emmy and Grammy Award-winning comedian and actor, The Mack, Silver Streak, Stir Crazy, The Toy, Superman III
 - Roman Pucinski, politician (Democrat), U.S. Representative 1959–73
 - Kirby Puckett, Hall of Fame center fielder for two-time World Series champion Minnesota Twins
 - Tom Pukstys, six-time U.S. javelin champion
 - George M. Pullman, industrialist, designer of Pullman sleeping car (born in New York)
 - Edward Mills Purcell, winner of Nobel Prize in Physics
 - David Purcey, MLB pitcher 2008–13
 - Todd Purdum, national editor and political correspondent for Vanity Fair
 - Ken Purdy, automotive writer
 - Tim Purpura, baseball executive
 - C. C. Pyle, sports promoter
 - Mike Pyle, center for Chicago Bears 1961–69 (born in Iowa)
 
Q
- Mike Quade, coach and manager for Chicago Cubs
 - John Qualen, actor, Casablanca, The Grapes of Wrath, The Searchers (born in Canada)
 - William Quarter, first Bishop of Chicago (born in Ireland)
 - John Francis Queeny, founder of Monsanto
 - Joel Quenneville, coach of three-time NHL champion Chicago Blackhawks (born in Canada)
 - Jeff Query, wide receiver for Green Bay Packers and Cincinnati Bengals
 - Smiley Quick, pro golfer
 - Allie Quigley, basketball player for DePaul and 2021 WNBA champion Chicago Sky
 - Mike Quigley, politician (Democrat), U.S. Representative
 - Elaine Quijano, television journalist
 - Frank Quilici, player, coach and manager for Minnesota Twins
 - Peter Quillin, middleweight boxer
 - Jack Quinlan, sportscaster
 - Maeve Quinlan, tennis player and actress, The Bold and the Beautiful, South of Nowhere
 - Michael R. Quinlan, chairman of Loyola and McDonald's
 - Aidan Quinn, actor, Legends of the Fall, Benny and Joon, Michael Collins, Avalon, Mary Shelley's Frankenstein, Elementary
 - Declan Quinn, cinematographer, Leaving Las Vegas, Vanity Fair, Hamilton
 - Jeff Quinn, football coach
 - Louis Quinn, actor, 77 Sunset Strip
 - Pat Quinn, politician (Democrat), attorney, state treasurer, Governor of Illinois 2009–14
 - Adolfo "Shabba Doo" Quiñones, actor, dancer, choreographer
 
R
Ra–Rd
- Charles Radbourn, Hall of Fame baseball pitcher (born in New York)
 - Ted Radcliffe, pro baseball player 1928-46 (born in Alabama)
 - Doug Rader, MLB infielder 1967-77, manager of Texas Rangers, Chicago White Sox, California Angels
 - Phil Radford, environmental leader, Greenpeace executive director
 - Bill Radovich, football player and actor
 - Sondra Radvanovsky, opera soprano
 - Zoe Rae, silent-film actress
 - Robert O. Ragland, film score composer
 - Tom Railsback, politician (Republican), eight-term U.S. Representative
 - Henry Thomas Rainey, politician (Democrat), U.S. Representative 1903–34, Speaker of the House under FDR
 - John W. Rainey, U.S. Representative 1918–23
 - Mamie Rallins, hurdler, coach, two-time Olympian
 - Buck Ram, songwriter, "Only You", "The Great Pretender"
 - Sendhil Ramamurthy, actor, Heroes, Beauty & the Beast, Covert Affairs
 - Harold Ramis, actor, director, writer SCTV, Ghostbusters, Caddyshack, Stripes, Groundhog Day, National Lampoon's Vacation
 - Charles H. Ramsey, police commissioner of Philadelphia 2008-16, police chief of Washington, D.C. 1998-2007
 - Edwin Ramsey, U.S. Army officer, guerrilla leader during World War II Japanese occupation of the Philippines
 - Lorene Ramsey, softball, basketball Hall of Famer (born in Missouri)
 - Ray Ramsey, defensive back for Chicago Cardinals
 - Bill Rancic, television personality, The Apprentice, Giuliana and Bill
 - William Rand, founder of Skokie-based Rand McNally (born in Massachusetts)
 - Clarence B. Randall, chairman of Inland Steel, presidential advisor (born in New York)
 - Martha Randall, swimmer, bronze medalist in 1964 Summer Olympics
 - Rebel Randall, actress, radio personality
 - Tony Randazzo, MLB umpire
 - Wayne Randazzo, MLB broadcaster for Los Angeles Angels
 - Betsy Randle, actress, Boy Meets World
 - Brian Randle, NBA coach and former Israeli Basketball Premier League player
 - Chasson Randle, pro basketball player
 - Antwaan Randle El, NFL wide receiver 2002-10, played for Super Bowl XL champion Pittsburgh Steelers
 - Kerri Randles, actress
 - Isabel Randolph, actress
 - Thomas E. G. Ransom, Civil War general, Ransom, Illinois named for him (born in Vermont)
 - Kwame Raoul, 42nd Illinois Attorney General
 - Frederic Raphael, Oscar-winning screenwriter, Darling, Two for the Road
 - Adam Rapp, novelist, playwright, screenwriter, musician, film director
 - Anthony Rapp, actor, singer, A Beautiful Mind, Rent, Dazed and Confused, Road Trip
 - David Rasche, actor, Succession, United 93, Sledge Hammer!
 - Wayne Rasmussen, defensive back for Detroit Lions 1964–72
 - John Ratcliffe, Republican Congressman from Texas 2015-20
 - George Ratkovicz, pro basketball player
 - Heather Rattray, actress, As the World Turns, Guiding Light
 - Green Berry Raum, brigadier general, chief of Internal Revenue Service 1876–83
 - Bruce Rauner, politician (Republican), Governor of Illinois 2015-19
 - John Aaron Rawlins, Civil War officer, U.S. Secretary of War
 - Lou Rawls, soul, jazz and blues singer and actor, winner of three Grammy Awards
 - Charles Ray, actor, producer, director
 - Hugh Ray, football official, Pro Football Hall of Fame
 - James Earl Ray, carried out April 1968 assassination of Martin Luther King Jr.
 - Joie Ray, three-time Olympian, runner in Track Hall of Fame
 - Lyman Beecher Ray, lieutenant governor 1889–93 (born in Vermont)
 - Gene Rayburn, television personality, Match Game
 - Benjamin Wright Raymond, third Mayor of Chicago (born in New York)
 - Bugs Raymond, MLB pitcher 1904–11
 - Robin Raymond, actress, There's No Business Like Show Business
 - Ray Rayner, Chicago television personality (born in New York)
 
Re–Rh
- Jack Reagan, father of President Ronald Reagan
 - Nancy Reagan, actress, 1981–89 First Lady of the United States (born in New York)
 - Neil Reagan, radio-TV executive, older brother of Ronald Reagan
 - Nelle Wilson Reagan, mother of Ronald Reagan
 - Ronald Reagan, actor, politician (Republican), Governor of California and 40th President of the United States (born in Tampico, Illinois)
 - Billy Reay, won 516 games as Chicago Blackhawks coach (born in Canada)
 - Eugene Record, singer, The Chi-Lites
 - William Reddick, businessman, philanthropist, politician
 - Jheri Redding, hair care entrepreneur
 - Quinn Redeker, actor, screenwriter, The Young and the Restless, Days of Our Lives, Dan Raven, The Deer Hunter
 - Courtney Reed, actress
 - Dizzy Reed, musician, Guns N' Roses
 - James F. Reed, organizer of Donner Party (born in Ireland)
 - Jeff Reed, MLB catcher 1984–2000
 - Jimmy Reed, guitarist in Blues Hall of Fame (born in Mississippi)
 - John Shedd Reed, president of Atchison, Topeka and Santa Fe Railway
 - Kennedy J. Reed, theoretical atomic physicist
 - Robert Reed, actor, Mike Brady on The Brady Bunch
 - Rondi Reed, stage actress, singer and performer
 - Tommy Rees, quarterback for Notre Dame 2010–13
 - George Reeves, actor, Superman (born in Iowa)
 - Tim Regan, pro soccer player
 - Henry Regnery, publisher, founder of Regnery Publishing
 - Wally Rehg, MLB player 1912–19
 - Kathy Reichs, crime writer, forensic anthropologist, academic
 - Charlotte Thompson Reid, singer, politician (Republican), U.S. Representative 1963–71
 - Frank R. Reid, attorney in court-martial of General Billy Mitchell, U.S. Representative 1923–35
 - Joe Reiff, basketball All-American for Northwestern
 - John Reilly, actor, Passions, Sunset Beach, Iron Man
 - John C. Reilly, actor, Talladega Nights, Step Brothers, Chicago, Gangs of New York, The Perfect Storm, Wreck-It Ralph
 - Ed Reimers, television announcer
 - Johan Reinhard, explorer
 - Bill Reinhardt, musician and bandleader
 - Haley Reinhart, singer, American Idol
 - Jerry Reinsdorf, owner of Chicago White Sox and Chicago Bulls (born in New York)
 - Todd Reirden, NHL player and coach
 - Bryan Rekar, pitcher for three MLB teams
 - Pat Renella, actor, Bullitt
 - Marcus Reno, Civil War officer, served with Gen. Custer in Battle of the Little Bighorn
 - Nancy Reno, beach volleyball player
 - Pug Rentner, halfback, College Football Hall of Fame player for Northwestern
 - REO Speedwagon, rock band from Champaign
 - Ken Retzer, MLB catcher 1961–64
 - Paul Reuschel, pitcher for Chicago Cubs 1975–79
 - Rick Reuschel, pitcher for five Major League teams, three-time All-Star
 - Ryan Tseko, Real Estate Executive and Pilot
 - Katherine Reutter, speed skater, 2011 world champion, medalist in 2010 Vancouver Olympics
 - Nellie Revell, journalist, publicist
 - Frank Reynolds, Chicago and ABC newscaster (born in Indiana)
 - John Reynolds, judge, U.S. Representative, Governor of Illinois 1830–34 (born in Pennsylvania)
 - Marcellas Reynolds, actor, fashion stylist, entertainment reporter, TV host
 - Virginia Richmond Reynolds, artist
 - Wellington J. Reynolds, artist
 - La Julia Rhea, opera singer
 - John Rheinecker, pitcher for Texas Rangers 2006–07
 - Shonda Rhimes, television producer, creator, Scandal, Grey's Anatomy
 - William C. Rhoden, sports journalist
 - Betty Jane Rhodes, singer, actress, Sweater Girl, The Fleet's In
 - Jennifer Rhodes, actress, Charmed, Heathers
 
Ri–Rn
- Paul Ricca, mobster with Chicago Outfit
 - John Blake Rice, actor, producer, Mayor of Chicago 1865–69 (born in Maryland)
 - Craig Rice, mystery novelist and screenwriter
 - Dan and Ada Rice, philanthropists, owners of 1965 Kentucky Derby winner Lucky Debonair
 - Fred Rice Jr., officer, superintendent, Chicago Police Department
 - Simeon Rice, defensive lineman for Illinois and Super Bowl XXXVII champion Tampa Bay Buccaneers
 - Wallace Rice, poet, writer, designer of Flag of Chicago (born in Canada)
 - Bob Richards, pole vaulter, gold medalist 1952 Helsinki Olympics and 1956 Melbourne Olympics
 - Carol Richards, singer, radio and television performer
 - Denise Richards, actress, The World Is Not Enough, Denise Richards: It's Complicated
 - Cathy Richardson, singer, Jefferson Starship
 - Lee Richardson, actor, Prizzi's Honor, Prince of the City
 - Quentin Richardson, player for five NBA teams
 - Salli Richardson, actress, Eureka, Gargoyles, Family Law
 - Sy Richardson, actor, Pushing Daisies
 - William Alexander Richardson, governor of Nebraska territory, U.S. Senator of Illinois (born in Kentucky)
 - Lionel Richie, multiple Grammy Award-winning singer in Rock and Roll Hall of Fame (born in Alabama)
 - Julius B. Richmond, U.S. Surgeon General 1977–81
 - Steve Richmond, defenseman for four NHL teams
 - Andy Richter, actor, comedian, Late Night with Conan O'Brien, Madagascar films & cartoons
 - Joyce Ricketts, pro baseball player
 - Laura Ricketts, lawyer, co-owner of Chicago Cubs (born in Nebraska)
 - Tom Ricketts, banker, owner and chairman of Cubs (born in Nebraska)
 - Todd Ricketts, businessman, co-owner of Cubs (born in Nebraska)
 - Hyman G. Rickover, admiral, attended Marshall High School in Chicago (born in Poland)
 - Lucille Ricksen, silent film actress
 - John Ridgely, actor, The Big Sleep, Destination Tokyo
 - John Riegger, golfer
 - Marty Riessen, tennis player, US Open, French Open, Wimbledon doubles and mixed doubles champion
 - Dorothy Comiskey Rigney, owner of Chicago White Sox 1956–58
 - Johnny Rigney, White Sox pitcher and general manager
 - Boots Riley, rapper, producer
 - Ida Morey Riley, founder of Columbia College Chicago
 - Jack Riley, Northwestern player in College Football Hall of Fame, silver medalist 1932 Olympic wrestling
 - Patrick William Riordan, archbishop of San Francisco 1884–1914 (born in Canada)
 - Minnie Riperton, singer, "Lovin' You", mother of Maya Rudolph
 - Wally Ris, swimmer, two-time NCAA champion, two 1948 Olympic golds
 - Rise Against, rock band from Chicago
 - Bill Risley, pitcher for three MLB teams
 - Laura J. Rittenhouse, activist, writer, poet, clubwoman
 - Doc Rivers, NBA point guard 1983-96, head coach of four teams
 - Mike Rizzo, general manager of Washington Nationals
 - Rick Rizzs, baseball broadcaster
 
Ro–Rt
- Tanner Roark, MLB pitcher 2013-21
 - Jason Robards, Oscar-winning actor, A Thousand Clowns, All the President's Men, Julia, Once Upon a Time in the West, Parenthood, Philadelphia
 - Jason Robards Sr., actor (born in Michigan)
 - Kevin Roberson, MLB outfielder 1993–96
 - Gale Robbins, singer, model and actress, Calamity Jane, The Barkleys of Broadway, Three Little Words
 - Leona Roberts, actress, Gone With the Wind
 - Robin Roberts, Hall of Fame starting pitcher primarily for Philadelphia Phillies, won 286 games
 - Sue Roberts, golfer
 - Nan C. Robertson, journalist, 1983 Pulitzer Prize
 - Angela Robinson, director, screenwriter, producer, True Blood, The L Word, Hung
 - Arthur B. Robinson, biochemist, politician
 - Betty Robinson, sprinter, gold medalist at 1928 and 1936 Olympics
 - Craig Robinson, actor, comedian, The Office, Last Comic Standing, Hot Tub Time Machine, This Is the End
 - Craig Robinson, basketball coach, brother of Michelle Obama
 - Flynn Robinson, guard for four NBA teams
 - Frank M. Robinson, author
 - John McCracken Robinson, lawyer, U.S. Senator of Illinois 1830–41 (born in Kentucky)
 - Kelsey Robinson, indoor volleyball player
 - Marian Shields Robinson, mother-in-law of President Barack Obama
 - Will Robinson, basketball coach for Illinois State, first African-American head coach at Division I school (born in North Carolina)
 - Bill Robinzine, DePaul and pro basketball player
 - Lelia P. Roby, philanthropist; founder, Ladies of the Grand Army of the Republic
 - Mason Rocca, Princeton and pro basketball player
 - James Roche, CEO and chairman of General Motors 1965–71
 - John A. Roche, president of elevated railway, Mayor of Chicago 1887–89 (born in New York)
 - Elizabeth Rochford, judge, Supreme Court of Illinois
 - Sharon Percy Rockefeller, first lady of West Virginia 1977-85 (born in California)
 - Knute Rockne, College Football Hall of Fame head coach for Notre Dame Fighting Irish (born in Norway)
 - George Lincoln Rockwell, founder of American Nazi Party
 - Robert Rockwell, actor, Our Miss Brooks, The Man from Blackhawk, Lassie, The Red Menace
 - Leo Rodak, boxer
 - Steve Rodby, musician
 - William A. Rodenberg, 10-term U.S. Representative
 - Mark Rodenhauser, NFL center 1987–99
 - Jimmy Rodgers, head coach of Minnesota Timberwolves, Boston Celtics
 - Dorothy Howell Rodham, mother of Hillary Clinton
 - Hugh Rodham, lawyer, brother of Hillary Clinton
 - Freddy Rodríguez, actor, Six Feet Under, Ugly Betty, Planet Terror
 - Francisco Rodriguez, boxer (born in Mexico)
 - Gina Rodriguez, actress, Jane the Virgin, The Bold and the Beautiful
 - Richard Roeper, columnist, film critic, co-host of At the Movies
 - Billy Rogell, MLB infielder 1925–40
 - Annette Rogers, sprinter, relay gold medalist, 1932 and 1936 Olympics
 - Carl Rogers, prominent psychologist
 - Desiree Rogers, CEO of Johnson Publishing (born in Louisiana)
 - Jimmy Rogers, blues musician (born in Mississippi)
 - John W. Rogers Jr., founder of Ariel Capital, head of Barack Obama inauguration committee
 - Michael S. Rogers, admiral, director of National Security Agency
 - Patience D. Roggensack, chief justice, Wisconsin Supreme Court 2015-21
 - Len Rohde, lineman for San Francisco 49ers 1960–74
 - Mark Romanek, Grammy-winning music video and film director, One Hour Photo, Never Let Me Go
 - Christina Romer, chair of Council of Economic Advisers under Barack Obama
 - Miles Park Romney, builder, Mormon leader, great-grandfather of Mitt Romney
 - Tony Romo, quarterback, Eastern Illinois and Dallas Cowboys (born in California)
 - Michael Rooker, actor, Cliffhanger, Days of Thunder, Guardians of the Galaxy (born in Alabama)
 - John E. Rooney, CEO of U.S. Cellular 2000-10
 - Sean Rooney, volleyball player, NCAA champion at Pepperdine, gold medalist at 2008 Beijing Olympics
 - John Root, architect
 - Adam Rosales, MLB infielder 2008-18
 - Derrick Rose, guard for New York Knicks, top pick of 2008 NBA draft, 2008–09 NBA Rookie of the Year
 - Fred Rose, songwriter, Country Music Hall of Fame (born in Indiana)
 - Helen Rose, Oscar-winning costume designer
 - Roger Rose, actor, voice actor, former VH1 VJ, Monsters and Mysteries in America, The Tick, Quack Pack, Happy Feet
 - Timothy M. Rose, actor, puppeteer, Return of the Jedi, The Dark Crystal
 - Wesley Rose, music producer
 - Johnny Roselli, organized crime figure (born in Italy)
 - Jacky Rosen, U.S. Senator from Nevada
 - Clarke Rosenberg, American-Israeli basketball player
 - Milt Rosenberg, professor, radio host
 - Tom Rosenberg, film producer, Million Dollar Baby, The Hurricane, Runaway Bride, Underworld series
 - Frank Rosenthal, organized crime figure
 - Julius Rosenwald, philanthropist, president of Sears, Roebuck & Company, founder of Museum of Science and Industry
 - Lessing J. Rosenwald, president of Sears
 - Peter Roskam, politician (Republican), U.S. Representative 2007-19
 - Arthur Ross, Oscar-nominated screenwriter, Brubaker, The Great Race
 - Barney Ross, boxing world champion (born in New York)
 - Charlotte Ross, actress, NYPD Blue, Beggars and Choosers
 - Leonard Fulton Ross, Civil War general
 - Lewis W. Ross, lawyer, Mexican–American War officer, U.S. Representative (born in New York)
 - Ossian M. Ross, farmer, War of 1812 officer, founder of Lewistown and Havana (born in New York)
 - Ricco Ross, actor, Westbeach
 - Dan Rostenkowski, politician (Democrat), U.S. Representative 1959–95, chairman of House Ways and Means Committee
 - Marv Rotblatt, pitcher for Chicago White Sox 1949–52
 - Matt Roth, NFL defensive end 2005–11
 - Veronica Roth, author of Divergent series (born in New York)
 - Claude Rothgeb, football coach for Colorado State, Rice
 - Larry Rothschild, MLB manager and pitching coach
 - John L. Rotz, Hall of Fame jockey
 - Tom Rouen, punter for six NFL teams
 - Pants Rowland, manager of Chicago White Sox 1915-18 (born in Wisconsin)
 - Pleasant Rowland, founder of American Girl
 - Cynthia Rowley, fashion designer
 - Rosey Rowswell, baseball broadcaster
 - Bill Roy, U.S. Representative in Kansas 1971–75
 - Willy Roy, player and coach, Soccer Hall of Fame (born in Germany)
 - Stan Royer, infielder for St. Louis Cardinals 1961–64
 - Mike Royko, Pulitzer Prize-winning newspaper columnist
 - Andrew Rozdilsky Jr., ballpark mascot Andy the Clown
 
Ru–Rz
- Aaron Ruben, television producer and director, The Andy Griffith Show
 - Arthur Rubloff, real estate developer (born in Minnesota)
 - Jack Ruby, killer of Lee Harvey Oswald
 - J. Craig Ruby, basketball coach, Illinois 1922–36 (born in Iowa)
 - Dave Rudabaugh, Wild West outlaw
 - Ken Rudolph, catcher for four MLB teams
 - Kirk Rueter, pitcher for San Francisco Giants 1996–2005
 - Rudy Ruettiger, motivational speaker, Notre Dame football player, Rudy
 - Red Ruffing, Hall of Fame pitcher, six-time World Series champion with New York Yankees
 - Sarah Ruhl, playwright
 - Irene Ruhnke, pro baseball player
 - Joe Ruklick, Northwestern and NBA player
 - Julian Sidney Rumsey, shipping mogul, Mayor of Chicago 1861–62 (born in New York)
 - Donald Rumsfeld, politician (Republican), Secretary of Defense, White House Chief of Staff, U.S. Representative
 - Bobby Rush, politician (Democrat), U.S. Representative 1993-2023
 - Otis Rush, blues musician (born in Mississippi)
 - William A. Rusher, lawyer, columnist, publisher of National Review 1957-88
 - Marion Rushing, four-sport athlete for Southern Illinois, NFL linebacker
 - Cazzie Russell, member of College Basketball Hall of Fame, player for 1970 NBA champion New York Knicks
 - Chuck Russell, director, The Mask, Eraser
 - Gail Russell, actress, The Uninvited, Angel and the Badman, Wake of the Red Witch
 - Lewis Russell, actor, The Lost Weekend
 - Lillian Russell, early 20th Century singer and actress (born in Iowa)
 - Mary Doria Russell, novelist
 - Pee Wee Russell, jazz clarinetist
 - Marty Russo, U.S. Representative 1975–93
 - William Russo, jazz musician and composer
 - Edward B. Rust Jr., CEO of State Farm insurance
 - Joe Rutgens, defensive tackle for Washington Redskins 1961–69
 - Ann Rutledge, friend of Abraham Lincoln (born in Kentucky)
 - Dan Ryan Jr., businessman, president of Cook County Board of Commissioners
 - George Ryan, politician (Republican), Governor of Illinois 1999–2003, imprisoned 2007
 - Howard C. Ryan, judge, Supreme Court of Illinois 1970-90
 - Jack Ryan, banker, teacher, Senate candidate vs. Barack Obama
 - Jeri Ryan, actress, Star Trek: Voyager, Boston Public, 1989 Miss Illinois
 - Jim Ryan, Illinois attorney general 1995-2003
 - Rex Ryan, head coach for NFL's New York Jets, Buffalo Bills
 - Rob Ryan, defensive coordinator for two-time Super Bowl champion Kansas City Chiefs
 - Robert Ryan, actor, The Wild Bunch, The Dirty Dozen, The Set-Up, Crossfire, Bad Day at Black Rock, The Longest Day
 - Shawn Ryan, television producer and writer, The Shield, The Unit, Angel
 - Gary Rydstrom, film sound designer, seven-time Academy Award winner
 - Frank Rydzewski, pro and Notre Dame lineman
 - Michael Rye, radio and voice actor
 - Jules Rykovich, co-MVP of 1947 Rose Bowl for Illinois (born in Croatia)
 - Bob Ryland, tennis player and coach
 - Herbert Ryman, animator, helped design Disneyland
 - Lou Rymkus, NFL tackle, coach for Houston Oilers
 - Miro Rys, professional soccer player (born in Czechoslovakia)
 - Marc Rzepczynski, MLB relief pitcher 2009-18
 
S
Sa–Sb
- Lou Saban, head coach of NFL's Buffalo Bills, Denver Broncos and New England Patriots
 - Adolph J. Sabath, politician (Democrat), U.S. Representative 1907–52 (born in Czechoslovakia)
 - Bret Saberhagen, pitcher for Kansas City Royals, 1985 Cy Young Award winner and World Series MVP
 - Lenny Sachs, head coach of Loyola basketball 1923–42
 - Jonathan Sadowski, actor, Live Free or Die Hard, Young & Hungry
 - Craig Sager, sportscaster
 - Bernard Sahlins, founder of Second City comedy club
 - Susan Saint James, Emmy-winning actress, McMillan & Wife, Kate & Allie, Love at First Bite (born in California)
 - Pat Sajak, television personality, host of Wheel of Fortune
 - Sol Saks, screenwriter, creator of Bewitched (botn in New York)
 - Sheri Salata, president of Oprah Winfrey Network (born in Georgia)
 - Chic Sale, actor
 - Virginia Sale, actress
 - Edward S. Salomon, Civil War general, Chicago alderman, Governor of Washington 1870–72 (born in Denmark)
 - Jerome Sally, NFL tackle 1982–88
 - Waldo Salt, Oscar-winning screenwriter, Midnight Cowboy, Serpico
 - Carmen Salvino, bowler, charter member PBA Hall of Fame
 - Jeff Salzenstein, tennis player
 - Tony Sam, comedian
 - Bill Sampen, MLB pitcher 1990–94
 - Don Samuelson, Governor of Idaho 1967–71
 - Ulises Armand Sanabria, television pioneer
 - Kiele Sanchez, actress, Married to the Kellys, Related, Lost
 - Ryne Sandberg, Hall of Fame infielder for Chicago Cubs, manager of Philadelphia Phillies 2013–15 (born in Washington)
 - Carl Sandburg, iconic Pulitzer Prize-winning poet and journalist
 - Hugh Sanders, actor
 - Scott Sanderson, MLB pitcher 1978–96 (born in Michigan)
 - Tommy Sands, singer, actor, first husband of Nancy Sinatra
 - Jenny Sanford, banker, first lady of South Carolina 2003–10
 - George E. Sangmeister, U.S. Representative 1989-95, Will County district attorney
 - Evelyn Sanguinetti, lieutenant governor 2015-19 (born in Florida)
 - Olayinka Sanni, pro basketball player
 - David Santee, figure skater, two-time Olympian
 - Rick Santelli, editor for CNBC Business News network
 - Ron Santo, Hall of Fame third baseman for Cubs and White Sox, radio sportscaster (born in Washington)
 - Horatio Sanz, comedian, Saturday Night Live
 - Abe Saperstein, owner-coach, Harlem Globetrotters (born in England)
 - Lewis Hastings Sarett, chemist and inventor
 - Peter Sarsgaard, actor, An Education, Shattered Glass, Kinsey, Orphan, Blue Jasmine, The Batman
 - Louis Satterfield, musician with Earth, Wind & Fire
 - Doris E. Saunders, librarian and professor
 - Red Saunders, drummer (born in Tennessee)
 - Warner Saunders, Chicago television newscaster
 - Dan Savage, writer, creator of Savage Love
 - Fred Savage, actor, director, The Wonder Years, The Princess Bride, Austin Powers in Goldmember
 - Randy Savage, professional wrestler
 - Ted Savage, outfielder for eight MLB teams
 - Matt Savoie, Olympic figure skater
 - Eugene Sawyer, Mayor of Chicago 1987–89 (born in Alabama)
 - Ken Saydak, blues musician
 - Gale Sayers, Hall of Fame running back for Chicago Bears, athletic director at Southern Illinois in 1970s (born in Kansas)
 - Morgan Saylor, actress, Homeland, Blow the Man Down, Novitiate
 - George D. Sax, innovative banker
 
Sc–Sg
- Joseph Scalise, organized crime figure
 - J. Young Scammon, early Chicago settler, banker (born in Maine)
 - Richard Schaal, actor, first husband of Valerie Harper
 - Wendy Schaal, actress, American Dad!, It's a Living, Fantasy Island
 - George Schaefer, Emmy and Tony Award-winning director (born in Connecticut)
 - Germany Schaefer, MLB infielder 1901–18
 - Johnny Schaive, infielder for Washington Senators 1958–63
 - Jan Schakowsky, politician (Democrat), U.S. Representative since 1999
 - Ray Schalk, Hall of Fame catcher for Chicago White Sox
 - Andrew H. Schapiro, ambassador to Czech Republic 2014-17
 - Dan Schatzeder, pitcher for nine MLB teams
 - Molly Schaus, two-time Olympic hockey silver medalist (born in New Jersey)
 - Paul Scheuring, writer-director, Prison Break
 - Sharm Scheuerman, basketball player and head coach, Iowa
 - Jon Scheyer, basketball player and coach, Duke
 - Claire Schillace, pro baseball player
 - Bobby Schilling, U.S. Representative 2011-13
 - Phyllis Schlafly, conservative activist, author
 - Fred Schmidt, 1964 Olympic swimming gold medalist
 - Harv Schmidt, basketball player and coach at Illinois
 - Karl Patterson Schmidt, herpetologist, zoology curator at Chicago Natural History Museum
 - Lanny D. Schmidt, chemist, inventor, author, professor
 - John Michael Schmitz, pro football center
 - Aaron Schock, U.S. Representative, resigned from office 2015 (born in Minnesota)
 - Red Schoendienst, Hall of Fame second baseman for St. Louis Cardinals and Milwaukee Braves
 - Russ Schoene, pro basketball player
 - Dana Schoenfield, swimmer, 1972 Olympic silver medalist
 - Admiral Schofield, small forward for Washington Wizards (born in England)
 - Dick Schofield, MLB infielder for California Angels and Toronto Blue Jays
 - Ducky Schofield, MLB infielder 1953-71, member of 1960 World Series champion Pittsburgh Pirates
 - Michael Schofield, NFL lineman for Super Bowl 50 champion Denver Broncos
 - O'Brien Schofield, NFL linebacker for Super Bowl XLVIII champion Seattle Seahawks (born in South Carolina)
 - John Schommer, basketball Hall of Famer, University of Chicago
 - Jessy Schram, actress, Falling Skies, Chicago Med
 - Avery Schreiber, actor and comedian
 - Dorothy Schroeder, pro baseball player
 - Leonard W. Schuetz, U.S. Representative 1931–44 (born in Germany)
 - Fred Schulte, MLB outfielder 1927–37
 - Bill Schulz, panelist, producer, Fox's Red Eye w/ Greg Gutfeld
 - Don Schulze, MLB pitcher 1983–89
 - Joe Schultz, MLB player and manager
 - William Schutz, psychologist
 - Fred Schmidt, swimmer, gold and bronze medalist in 1964 Summer Olympics, Navy SEAL
 - Tony Schumacher, drag racer, seven-time NHRA champ
 - Joseph Schwantner, composer
 - Jim Schwantz, NFL linebacker 1992–98
 - Ed Schwartz, radio personality
 - Frederick Schwatka, U.S. Army lieutenant, noted explorer of northern Canada and Alaska
 - Emma Clara Schweer, oldest elected politician
 - Gloria Schweigerdt, professional baseball player
 - Rusty Schwimmer, actress, Twister, The Perfect Storm
 - Ignaz Schwinn, founder of bicycle company (born in Germany)
 - John T. Scopes, teacher, defendant in Scopes trial (born in Kentucky)
 - Thomas N. Scortia, novel adapted as The Towering Inferno
 - Bud Scott, jazz musician (born in Louisiana)
 - Mark Scott, actor, host of TV's Home Run Derby
 - Rick Scott, politician (Republican), Governor of Florida 2011-19, U.S. Senator
 - Stefanie Scott, actress, singer, A.N.T. Farm, Wreck-It Ralph
 - Stuart Scott, ESPN sportscaster
 - Walter Dill Scott, psychologist, president of Northwestern 1920–39
 - Gil Scott-Heron, jazz musician, Grammy Lifetime Achievement Award
 - Nancy Scranton, golfer
 - Edward Willis Scripps, newspaper publisher, founder of E.W. Scripps Company
 - Ellen Browning Scripps, journalist and philanthropist (born in England)
 - James E. Scripps, newspaper publisher (born in England)
 - Al Sears, saxophonist
 - Richard Warren Sears, businessman, co-founder of Sears, Roebuck and Company (born in Minnesota)
 - Amy Sedaris, actress and comedian, Strangers with Candy, At Home with Amy Sedaris, BoJack Horseman
 - E.C. Segar, creator of Popeye
 - Phil Seghi, general manager of Cleveland Indians 1973-85
 - Harry Gordon Selfridge, department store pioneer, founder of Selfridges (born in Wisconsin)
 - Rose Buckingham Selfridge, Chicago heiress
 - Kevin Seitzer, All-Star third baseman, Atlanta Braves hitting coach
 - William Nicholas Selig, motion picture pioneer
 - David Seltzer, director and screenwriter, Punchline, Shining Through, Bird on a Wire, The Omen
 - James Semple, U.S. Senator 1843–47 (born in Kentucky)
 - Tony Semple, NFL lineman 1994–2002
 - Bill Senn, NFL running back 1926–34
 - Mary Servoss, actress, In This Our Life
 - Ike Sewell, pioneer in Chicago-style pizza (born in Texas)
 - Mary Foot Seymour, law reporter, businesswoman, school founder, journalist
 
Sh
- Shabbona, 19th Century Native American leader
 - Shadows of Knight, rock band from Mt. Prospect
 - Dirk Shafer, actor and Playgirl model
 - Tom Shales, Pulitzer Prize-winning TV critic
 - John Shalikashvili, U.S. Army general, Chairman Joint Chiefs of Staff 1993-97 (born in Poland)
 - Ashton C. Shallenberger, Governor of Nebraska 1909–11, six-term U.S. Representative
 - Janet Shamlian, news correspondent for CBS and NBC
 - Mike Shanahan, head coach of NFL's Los Angeles Raiders, Denver Broncos, Washington Redskins
 - Garry Shandling, comedian and actor, The Larry Sanders Show
 - Howie Shanks, MLB outfielder 1912–25
 - Michael Shannon, actor, Boardwalk Empire, Take Shelter, Revolutionary Road, Man of Steel (born in Kentucky)
 - Mark Shapiro, executive with Endeavor talent agency, Six Flags, ESPN
 - Samuel H. Shapiro, lieutenant governor and 1968–69 Governor of Illinois
 - Shannon Sharpe, NFL tight end 1990–2003, three-time Super Bowl champion, Pro Football Hall of Fame, TV analyst
 - Sterling Sharpe, wide receiver, College Football Hall of Fame, Green Bay Packers 1988–94, TV analyst
 - Frank Shaughnessy, college football player and coach, pro baseball player and executive
 - Bernard Shaw, television journalist for CNN
 - Guy L. Shaw, U.S. Representative 1921–25
 - Howard Van Doren Shaw, architect
 - Stan Shaw, actor, The Boys in Company C, The Great Santini, Daylight, Snake Eyes, Harlem Nights
 - William Shawn, editor of The New Yorker from 1952 to 1987
 - Larry Shay, songwriter, "When You're Smiling"
 - John T. Shayne, milliner
 - Aaron Shea, NFL tight end 2000–06
 - John G. Shedd, president of Marshall Field & Company, philanthropist, founder of Shedd Aquarium (born in New Hampshire)
 - Vincent Sheean, war correspondent and author
 - Arthur Sheekman, screenwriter, Duck Soup, Some Came Running
 - Earl Sheely, 1920s first baseman for White Sox
 - Fulton J. Sheen, Roman Catholic Archbishop and television personality
 - Bernard J. Sheil, Roman Catholic Archbishop, founder of CYO
 - Edward Sheldon, playwright
 - Sidney Sheldon, author, Oscar-winning screenwriter, producer, I Dream of Jeannie, Hart to Hart, Annie Get Your Gun, The Other Side of Midnight
 - Derek Shelton, manager of Pittsburgh Pirates
 - Sam Shepard, actor, director, Pulitzer Prize-winning playwright, Fool for Love, The Right Stuff, The Pelican Brief, Baby Boom, The Notebook
 - Jean Shepherd, radio personality, writer and narrator of A Christmas Story
 - Sherri Shepherd, comedian, actress, co-host of The View
 - Trent Sherfield, NFL wide receiver
 - Jack Sheridan, MLB umpire 1890–1914
 - Philip Sheridan, Civil War general, led Great Chicago Fire reconstruction, ran Washington Park Race Track (born in New York)
 - Allan Sherman, comedy writer, song parodist
 - Alson Sherman, fire chief, Mayor of Chicago 1844–45 (born in Vermont)
 - Francis Cornwall Sherman, three-term Mayor of Chicago (born in Connecticut)
 - Francis Trowbridge Sherman, Civil War general (born in Connecticut)
 - Gene Sherman, Pulitzer Prize-winning journalist
 - Lawrence Yates Sherman, lieutenant governor, U.S. Senator 1913-21 (born in Ohio)
 - Brian Sherwin, art critic, curator, writer
 - Brad Sherwood, comedian, Whose Line Is It Anyway?
 - James Shields, Irish-born senator of Illinois, Minnesota and Missouri
 - Ren Shields, songwriter, "In the Good Old Summer Time"
 - Matthew Shiltz, quarterback in CFL
 - John Shimkus, politician (Republican), U.S. Representative 1997-2021
 - Katherine Shindle, actress and 1998 Miss America
 - Kiernan Shipka, actress, Sally Draper on Mad Men
 - George E. Shipley, U.S. Representative 1959–79
 - William L. Shirer, war correspondent, historian
 - Bernie Shively, All-American guard for Illinois, 1938-67 athletic director at Kentucky
 - Twila Shively, pro baseball player
 - William Shockley, Nobel Prize-winning physicist, co-inventor of the transistor
 - Vaughn Shoemaker, Pulitzer Prize-winning cartoonist
 - Lee Sholem, film director, The Redhead from Wyoming, Tarzan and the Slave Girl, Superman and the Mole Men
 - Bobby Short, cabaret singer, pianist and recording artist
 - Ed Short, executive with Chicago White Sox 1950–70
 - Luke Short, novelist
 - Rick Short, MLB player and scout
 - Gwynne Shotwell, president of SpaceX
 - Brian Shouse, MLB pitcher 1993–2009
 - Bobby Shriver, activist, writer and California politician
 - Maria Shriver, television journalist, author, 2003–11 first lady of California
 - David Shulkin, U.S. Secretary of Veterans Affairs
 - Richard B. Shull, actor, The Fortune, Unfaithfully Yours
 - George P. Shultz, U.S. Secretary of Labor 1969–70, Treasury 1972–74, Secretary of State 1982–89, Chicago professor (born in New York)
 - Iman Shumpert, NBA guard 2011-21
 - John Shurna, Northwestern basketball all-time leading scorer
 
Si–Sk
- Billy Sianis, founder of Billy Goat Tavern (born in Greece)
 - Drew Sidora, actress, That's So Raven
 - Thomas Siebel, technology executive, philanthropist
 - Don Siegel, film director, Dirty Harry, Charley Varrick, The Shootist, Invasion of the Body Snatchers, Coogan's Bluff
 - Jeremy Siegel, professor of finance at Wharton School of the University of Pennsylvania
 - Casey Siemaszko, actor, Breaking In, Of Mice and Men, NYPD Blue, Back to the Future parts 1 and 2
 - Nina Siemaszko, actress, The West Wing, The American President, License to Drive, Sinatra, Mystery Woman
 - Eric Sievers, tight end for San Diego Chargers 1981–90
 - Jack Sikma, Hall of Fame center for 1979 NBA champion Seattle SuperSonics
 - Paul Sills, original director of The Second City
 - Joe Silver, actor, You Light Up My Life, Deathtrap
 - Nate Silver, quarterback of first Notre Dame undefeated team, 1903
 - Shel Silverstein, cartoonist, screenwriter, author of children's books
 - Ken Silvestri, MLB catcher and coach
 - Bobby Simmons, guard for five NBA teams
 - Jade Simmons, concert pianist, 2000 Miss America runner-up
 - Liesel Pritzker Simmons, actress, heiress
 - Marty Simmons, basketball coach, Evansville University
 - Tony Simmons, NFL wide receiver 1998–2002
 - Bryan W. Simon, film and stage director
 - Paul Simon, politician (Democrat), U.S. Senator 1985–97, presidential candidate (born in Oregon)
 - Roger Simon, journalist, columnist for Politico
 - Scott Simon, program host for National Public Radio
 - Sheila Simon, law professor, 2011-15 lieutenant governor
 - S. Sylvan Simon, film director and producer, I Love Trouble, The Fuller Brush Man, Born Yesterday
 - Carole Simpson, radio and TV journalist
 - Diane Simpson-Bundy, two-time Olympian in rhythmic gymnastics
 - Edna Oakes Simpson, U.S. Representative 1959–61, widow of Sid Simpson
 - Sid Simpson, transportation executive, U.S. Representative 1943–58
 - Will Simpson, Olympic gold medalist in equestrian
 - Mike Singletary, Hall of Fame linebacker for Chicago Bears (born in Texas)
 - James Singleton, pro basketball player
 - Gary Sinise, Golden Globe and Emmy Award-winning actor, director, musician, CSI: NY, Forrest Gump, Apollo 13
 - Charlie Siringo, Chicago-based Pinkerton's detective (born in Texas)
 - Bob Sirott, radio and TV personality
 - Joseph J. Sisco, CIA officer and diplomat
 - Gene Siskel, film critic for Chicago Tribune, co-host of Siskel & Ebert
 - Sister Jean, chaplain and basketball personality at Loyola
 - George Skakel, industrialist, father of Ethel Kennedy
 - William V. Skall, Oscar-winning cinematographer
 - Bob Skelton, swimmer, 1924 Olympic gold medalist
 - Roe Skidmore, 1-for-1 for Cubs in lone MLB at-bat
 - Jeffrey Skilling, former president of Enron, convicted of multiple federal felony charges
 - Tom Skilling, meteorologist for WGN News
 - Cornelia Otis Skinner, actress and author
 - Frank Skinner, Oscar-nominated composer
 - Jane Skinner, TV journalist, wife of NFL Commissioner Roger Goodell
 - Samuel K. Skinner, U.S. Secretary of Transportation and White House Chief of Staff for President George H. W. Bush
 - Lou Skizas, MLB outfielder 1956–59
 - Peter Skoronski, offensive lineman for Northwestern, 11th pick of 2023 NFL Draft
 - Tony Skoronski, jockey
 - Bill "Moose" Skowron, MLB first baseman, five World Series championships with New York Yankees
 - Victor Skrebneski, photographer
 
Sl–Sn
- Jack Slade, gunfighter, Pony Express rider
 - Duke Slater, NFL tackle and College Football Hall of Famer
 - John Slater, physicist
 - James M. Slattery, U.S. Senate appointee
 - Chris Slayton, NFL defensive end
 - Martha Sleeper, actress, Spitfire, The Bells of St. Mary's
 - Grace Slick, lead singer of Jefferson Airplane, Jefferson Starship, composer of "White Rabbit"
 - Blake Sloan, NHL winger 1999–2004
 - Jerry Sloan, NBA All-Star player and coach for Chicago Bulls, coach of Utah Jazz, member of Hall of Fame
 - Gabriel Slonina, pro soccer goalkeeper
 - Jeff Sluman, pro golfer (born in New York)
 - Albion W. Small, sociologist and university professor (born in Maine)
 - Len Small, state treasurer and 1921–29 Governor of Illinois
 - Mike Small, pro golfer and coach
 - The Smashing Pumpkins, rock band from Chicago
 - Anne Smedinghoff, diplomat killed in Afghanistan
 - Ralph C. Smedley, founder of Toastmasters International
 - Jack Smiley, basketball player for Illinois
 - Adrian Smith, architect of Chicago's Trump Tower and Dubai's Burj Khalifa (world's tallest building)
 - Al Smith, basketball player in ABA 1971–75
 - Al Smith, MLB pitcher 1934–45
 - Art Smith, actor, In a Lonely Place, Ride the Pink Horse, Body and Soul
 - Frank L. Smith, U.S. Representative 1919–21
 - Giles Alexander Smith, Civil War general, politician (born in New York)
 - H. Allen Smith, journalist and humorist, Rhubarb
 - Hal Smith, MLB catcher 1955-64, played for 1960 World Series champion Pittsburgh Pirates
 - Hamilton O. Smith, microbiologist, 1978 Nobel Prize (born in New York)
 - Harry Smith, television news journalist
 - Henry Justin Smith, editor of Chicago Daily News
 - Jack Smith, MLB outfielder 1915–29
 - Jim Smith, wide receiver, won two Super Bowls with Pittsburgh Steelers
 - John C. Smith, Civil War general, politician (born in Pennsylvania)
 - John E. Smith, Civil War general, jeweler (born in Switzerland)
 - Joseph Smith, founder of Latter Day Saint movement (born in Vermont)
 - Kellita Smith, actress and model, The Bernie Mac Show
 - Lenzelle Smith Jr., player in Israel Basketball Premier League
 - Lonnie Smith, MLB outfielder, three-time World Series champion
 - Lovie Smith, head coach of Chicago Bears 2004-12, Illinois 2016-20 (born in Texas)
 - Lyall Smith, sports editor and executive
 - Patti Smith, singer, songwriter and poet, Rock and Roll Hall of Fame
 - Pinetop Smith, jazz pianist (born in Alabama)
 - Ralph Tyler Smith, completed U.S. Senate term of Everett Dirksen
 - Ron Smith, defensive back for five NFL teams
 - Sally Smith, mayor of Juneau, Alaska 2000–03
 - Sandra Smith, reporter for Fox Business Network
 - Sidney Smith, cartoonist
 - Tangela Smith, WNBA player 1998-2012, 2007 and 2009 champion
 - Theophilus W. Smith, law partner of Aaron Burr, impeached Illinois Supreme Court justice (born in New York)
 - Wendell Smith, sportswriter (born in Michigan)
 - Olivia Smoliga, swimmer, NCAA champion and Olympic gold medalist
 - Jake Smolinski, outfielder for Oakland A's
 - Henry Snapp, U.S. Representative 1871–73 (born in New York)
 - Howard M. Snapp, U.S. Representative 1903–11 (born in New York)
 - Phoebe Snetsinger, bird watcher
 - Brian Snitker, manager for Atlanta Braves, won 2021 World Series
 - Carrie Snodgress, Oscar-nominated actress, Diary of a Mad Housewife, The Fury, Murphy's Law, Pale Rider
 - Esther Snyder, co-founder of In-N-Out Burger
 - Franklyn Bliss Snyder, president of Northwestern University 1939-49
 - Jimmy Snyder, auto racer, runner-up in 1939 Indianapolis 500
 - Martin Snyder, gangster, husband of Ruth Etting
 - Ted Snyder, songwriter, "Who's Sorry Now?"
 
So–Ss
- Carol Sobieski, screenwriter, Annie, Fried Green Tomatoes, Casey's Shadow, Sarah, Plain and Tall
 - Ron Sobie, basketball player for DePaul, New York Knicks
 - Susan Solomon, chemist, MIT professor, Nobel Prize winner
 - Joey Soloway, TV and film writer, director
 - Georg Solti, conductor of Chicago Symphony Orchestra 1969–91 (born in Hungary)
 - Rafael Sorkin, physicist
 - Sammy Sosa, outfielder for White Sox and Cubs from 1989 to 2004 (born in Dominican Republic)
 - David Soul, actor, Starsky and Hutch, Here Come the Brides, The Yellow Rose; singer, "Don't Give Up on Us"
 - Olan Soule, actor
 - Soulja Boy, rapper
 - Eddie South, jazz violinist (born in Missouri)
 - Pete Souza, official White House photographer for Presidents Reagan and Obama (born in Massachusetts)
 - Judy Sowinski, skater in Roller Derby
 - Brock Spack, football coach, Illinois State
 - Vince Spadea, tennis player
 - Horatio Spafford, lawyer, hymn composer (born in New York)
 - Sarah Spain, sports journalist (born in Ohio)
 - Albert Spalding, athlete, co-founder of Spalding sporting goods
 - John Spalding, Roman Catholic Bishop and co-founder of The Catholic University of America
 - William A.J. Sparks, U.S. Representative 1875–83 (born in Indiana)
 - Graham Spanier, president of Penn State University 1995-2011 (born in South Africa)
 - Muggsy Spanier, jazz musician
 - Otis Spann, pianist in Blues Hall of Fame (born in Mississippi)
 - Garret Sparks, pro hockey goaltender
 - Jeff Speakman, martial artist, actor, The Perfect Weapon
 - Richard Speck, mass murderer
 - Dave Spector, Japan television personality
 - Jonathan Spector, soccer player for Birmingham City F.C.
 - Mac Speedie, wide receiver for Cleveland Browns 1946–52, head coach for Denver Broncos 1964–66
 - Donald Spero, physicist, Olympic rower
 - Lawrence Sperry, aviation pioneer
 - August Spies, convicted anarchist of Haymarket affair (born in Germany)
 - Ed Spiezio, infielder for St. Louis Cardinals and San Diego Padres
 - Scott Spiezio, infielder for four Major League teams; 2002, 2006 World Series champion
 - Anthony Spilotro, mobster and enforcer for Chicago Outfit
 - Alfred Henry Spink, founder of The Sporting News (born in Canada)
 - Scipio Spinks, MLB pitcher 1969–73
 - Jim Spivey, middle-distance runner, three-time Olympian
 - Paul Splittorff, pitcher for Kansas City Royals 1970–84 (born in Indiana)
 - Erik Spoelstra, head coach for two-time NBA champion Miami Heat
 - Viola Spolin, drama and improv teacher
 - George Kirke Spoor, film industry pioneer
 - Jerry Springer, Chicago-based TV personality (born in England)
 - William L. Springer, U.S. Representative 1951–73
 - William M. Springer, U.S. Representative 1875–95 (born in Indiana)
 - Ed Sprinkle, Hall of Fame end for Chicago Bears (born in Texas)
 - June Squibb, Oscar-nominated actress, Nebraska, About Schmidt
 
Sta–Std
- Dewayne Staats, sportscaster (born in Missouri)
 - Brian Stack, comedy writer
 - Eddie Stack, MLB pitcher 1910–14
 - Jim Stack, NBA executive, two-time Northwestern MVP
 - Marv Staehle, infielder for Chicago White Sox 1964–67
 - Jimmy Stafford, lead guitarist for Train
 - Michelle Stafford, actress, The Young and the Restless
 - Amos Alonzo Stagg, College Hall of Fame football coach and athlete, creator of the lateral pass and helmet
 - Amos Alonzo Stagg Jr., college football player and coach
 - Paul Stagg, college football player and coach
 - Jake Stahl, MLB player and manager, 1912 World Series
 - Larry Stahl, outfielder for four MLB teams
 - Michael Stahl-David, actor, The Black Donnellys, Cloverfield
 - A.E. Staley, food mogul, founder of football's Decatur Staleys (who became Chicago Bears)
 - Harry Staley, MLB pitcher 1888–95
 - Kevin Stallings, basketball coach, Illinois State, Vanderbilt
 - Dino Stamatopoulos, comedy writer, actor, producer
 - Lee Stange, pitcher for four MLB teams
 - Don Stanhouse, pitcher for four MLB teams
 - Pete Stanicek, MLB player
 - Steve Stanicek, MLB player
 - Aileen Stanley, early 20th Century singer
 - Dolph Stanley, basketball coach
 - Florence Stanley, actress, Fiddler on the Roof, Fish
 - Louise Stanley, actress, Sky Bandits, Yukon Flight
 - Walter Stanley, NFL wide receiver
 - The Staple Singers, gospel group, Grammy Lifetime Achievement Award
 - Mavis Staples, gospel singer, 2017 Blues Hall of Fame inductee
 - Tim Stapleton, NHL center 2008–12
 - Ellen Gates Starr, social reformer and co-founder of Hull House
 - Helen Ekin Starrett, president, Illinois Woman's Press Association
 - Vincent Starrett, early 20th Century journalist
 - Todd Stashwick, actor, The Riches
 - Harry Statham, college basketball coach
 - Jigger Statz, MLB outfielder 1919–28
 
Ste–Stn
- Jack Steadman, president, general manager of NFL's Kansas City Chiefs 1960-89
 - Steamboat Willie, Dixieland jazz musician
 - Myrtle Stedman, singer and actress
 - Claude Steele, provost at Columbia, University of California
 - Dan Steele, two-time Olympian in bobsled, NCAA champion hurdler
 - Shelby Steele, columnist, documentary filmmaker, author of White Guilt
 - Miriam Steever, pro tennis player
 - Walter Steffen, All-American quarterback, University of Chicago
 - Cindy Stein, women's basketball coach, Missouri and Southern Illinois
 - James R. Stein, TV writer and producer, America 2-Night, Fernwood 2 Night, Son of the Beach
 - Jill Stein, physician, activist, Green Party politician
 - Eric Steinbach, NFL offensive lineman 2003–12
 - Jack Steinberger, physicist, Nobel Prize winner
 - Ruth Ann Steinhagen, shot ballplayer Eddie Waitkus, inspired The Natural
 - John Henry Stelle, lieutenant governor 1937–40, briefly Governor of Illinois
 - Rick Stelmaszek, catcher and bullpen coach for Minnesota Twins
 - Marilee Stepan, swimmer, 1952 Olympic bronze medalist
 - Donald Stephens, 13-term mayor of Rosemont, Illinois
 - Michael Stephens, pro soccer player
 - Benjamin Stephenson, militia commander, politician, writer of state constitution (born in Pennsylvania)
 - John Allen Sterling, U.S. Representative 1903–18
 - Thomas Sterling, Springfield attorney, U.S. Senator of South Dakota 1913–25 (born in Ohio)
 - Lee Stern, six-decade member of Chicago Board of Trade, founder-president of Chicago Sting pro soccer
 - Dutch Sternaman, football player, co-owner of Decatur Staleys (who became Chicago Bears)
 - Joey Sternaman, 1920s pro football quarterback
 - Dodie Stevens, singer, "Pink Shoe Laces"
 - Fisher Stevens, actor, producer, director, Early Edition, Short Circuit, Stand Up Guys, Succession
 - John Paul Stevens, attorney, Supreme Court Justice 1975–2010, third-longest tenure in court's history
 - Adlai Stevenson I, Illinois congressman, U.S. postmaster general, 23rd Vice President of the United States 1893–97 (born in Kentucky)
 - Adlai Stevenson II, attorney, politician (Democrat) Governor of Illinois, Ambassador to the United Nations, presidential candidate in 1952 and 1956 (born in California)
 - Adlai Stevenson III, politician (Democrat), congressman and U.S. Senator from Illinois 1970–81
 - Lewis Stevenson, Illinois secretary of state 1914–17, father of Adlai Stevenson II
 - McLean Stevenson, actor, M*A*S*H, Hello, Larry
 - William Stevenson, Olympic gold medalist, college president, ambassador
 - Helen J. Stewart, pioneer, postmaster of Las Vegas
 - James B. Stewart, journalist, 1988 Pulitzer Prize
 - Levi Stewart, Mormon pioneer, associate of Brigham Young
 - Lynn D. Stewart, lineman for Illinois in 1964 Rose Bowl, co-founder of Hooters restaurants
 - David Ogden Stiers, actor, orchestral conductor; M*A*S*H, The Dead Zone, Doc Hollywood, Better Off Dead
 - Isaiah Stillman, militia commander, Black Hawk War (born in Massachusetts)
 - Darryl Stingley, NFL receiver, left quadriplegic by injury
 - Howard St. John, actor, Born Yesterday, Li'l Abner, One, Two, Three
 
Sto–Stz
- Barbara Stock, actress, Spenser: For Hire
 - Frederick Stock, 37-year director of Chicago Symphony Orchestra (born in Germany)
 - Milt Stock, MLB third baseman 1913–26
 - James Stockdale, one of U.S. Navy's most highly decorated officers, 1992 vice-presidential candidate
 - Dejan Stojanović, poet, writer, essayist (born in Serbia)
 - Johnny Stompanato, gangster, killed by daughter of Lana Turner
 - Cynthia Stone, actress, wife of Jack Lemmon
 - Dean Stone, pitcher for six MLB teams
 - Melville E. Stone, publisher, founder of Chicago Daily News, manager of Associated Press
 - Steve Stone, pitcher and broadcaster, Cubs and White Sox (born in Ohio)
 - W. Clement Stone, philanthropist, self-help author
 - Steve Stonebreaker, NFL linebacker 1962–68
 - Bill Stoneman, MLB pitcher 1967-74, general manager of Los Angeles Angels 1999-2007
 - Wilbur F. Storey, journalist (born in Vermont)
 - Hannah Storm, ESPN sportscaster
 - Lauren Storm, actress, Flight 29 Down
 - John Stossel, consumer reporter, investigative journalist, author
 - Jean Stothert, mayor of Omaha, Nebraska
 - Eric Stout, MLB pitcher
 - Shirley Stovroff, pro baseball player
 - Otto Stowe, NFL wide receiver 1971–74
 - Michael Stoyanov, actor, TV comedy writer, Blossom
 - Win Stracke, folk musician
 - Hank Stram, Pro Football Hall of Fame coach of Kansas City Chiefs
 - William Stratton, politician (Republican), Governor of Illinois 1953–61
 - Michael W. Straus, editor, director of U.S. reclamation under Harry Truman
 - The Brothers Strause, directing duo, special effects artists
 - Kevin Streelman, pro golfer
 - Tai Streets, Michigan football and basketball player, San Francisco 49ers wide receiver
 - Steve Stricker, pro golfer, University of Illinois player (born in Wisconsin)
 - Lee Strobel, Christian apologetic author
 - John Stroger, president of Cook County Commissioners 1994–2006
 - Cal Strong, Olympic water polo medalist
 - Cecily Strong, comedian, Saturday Night Live
 - Robert H. Strotz, economist, Northwestern University president 1970-84
 - Max Strus, basketball player for DePaul and Miami Heat
 - Barbara Stuart, television actress
 - John Stuart, CEO of Quaker Oats 1922-53
 - John T. Stuart, law partner of Abe Lincoln, U.S. Representative (born in Kentucky)
 - R. Douglas Stuart, U.S. ambassador to Canada
 - R. Douglas Stuart Jr., executive of Quaker Oats, ambassador to Norway
 - Andy Studebaker, NFL linebacker 2008-15
 - Quint Studer, healthcare entrepreneur
 - Mary Lou Studnicka, player in All-American Girls Baseball League
 - James J. Stukel, university president
 - Patrick Stump, lead singer of band Fall Out Boy
 - John Sturges, Oscar-nominated film director, The Magnificent Seven, Gunfight at the O.K. Corral, The Great Escape
 - Preston Sturges, director and Oscar-winning screenwriter, The Lady Eve, Sullivan's Travels, The Miracle of Morgan's Creek
 
Su–Sz
- Todd Sucherman, drummer for Styx
 - Bill Sudakis, infielder for six Major League teams
 - Margaret Ashmore Sudduth, educator, editor, social reformer
 - Harry Sukman, Oscar-winning composer
 - Billy Sullivan Jr., MLB catcher 1931–47
 - Gerry Sullivan, offensive lineman for Cleveland Browns 1974–81
 - Joe Sullivan, MLB pitcher 1935–41
 - Louis Sullivan, architect (born in Massachusetts)
 - McKey Sullivan, fashion model, winner of America’s Next Top Model Cycle 11
 - Mike Sullivan, NFL lineman and coach
 - Hope Summers, actress, The Andy Griffith Show
 - Jessie Sumner, U.S. Representative 1939-47
 - Billy Sunday, ballplayer and evangelist (born in Iowa)
 - Helen Thompson Sunday, evangelist
 - Jim Sundberg, MLB catcher 1974–89, six Gold Glove Awards
 - Eliza R. Sunderland, writer, educator, lecturer, women's rights advocate
 - Don Sundquist, Governor of Tennessee 1995–2003
 - Daniel Sunjata, actor, Rescue Me, Law & Order: Special Victims Unit, The Devil Wears Prada
 - Tom Sunkel, MLB pitcher 1937–44
 - Evar Swanson, MLB outfielder 1929–34
 - Gloria Swanson, Oscar-nominated, Golden Globe-winning actress, Sunset Boulevard, The Trespasser, Airport 1975
 - Gladys Swarthout, opera singer (born in Missouri)
 - Aaron Swartz, computer programmer, writer
 - Ed Sweeney, MLB catcher 1908–1919
 - Blanche Sweet, actress, Anna Christie
 - Lynn Sweet, Washington bureau chief, Chicago Sun-Times
 - Nancy Swider-Peltz, speed skater, four-time Olympian
 - George Bell Swift, two-term Mayor of Chicago (born in Ohio)
 - Gustavus Franklin Swift, meat-packing entrepreneur, founder of Swift & Co. (born in Massachusetts)
 - Emerson Swinford, musician
 - Bob Swisher, running back for Chicago Bears 1938–41
 - Ann Swisshelm, 2014 Olympian in curling
 - Carl Switzer, actor, "Alfalfa" in Our Gang comedies
 - Ken Swofford, actor, Ellery Queen, Murder, She Wrote
 - Keith Szarabajka, actor, The Dark Knight, We Were Soldiers
 - Stan Szukala, pro basketball player
 
T
Ta–Tg
- Lorado Taft, sculptor
 - Joe Tait, sportscaster for Cleveland Cavaliers
 - Carlos Talbott, U.S. Air Force general
 - Maria Tallchief, ballerina, Chicago Lyric Opera director (born in Oklahoma)
 - Jill Talley, actress, Little Miss Sunshine, The Boondocks, Mr. Show
 - Shel Talmy, 1960s record producer, songwriter, arranger
 - Tampa Red, musician in Blues Hall of Fame (born in Georgia)
 - Daniel M. Tani, astronaut (born in Pennsylvania)
 - Bazy Tankersley, horse breeder and publisher
 - Antwon Tanner, actor, One Tree Hill
 - John Riley Tanner, Governor of Illinois 1897–1901 (born in Indiana)
 - Joseph R. Tanner, astronaut
 - Alex Tanney, NFL quarterback and coach
 - Dorothea Tanning, artist
 - Lawrence Tanter, public address announcer, Los Angeles Lakers
 - El Tappe, catcher and coach for Chicago Cubs
 - Bill Tate, MVP of 1952 Rose Bowl, head coach at Wake Forest
 - Larenz Tate, actor, Dead Presidents, Menace II Society, Why Do Fools Fall in Love, Ray, The Postman
 - Mark Tatge, journalist
 - Mike Tauchman, MLB outfielder
 - Norman Taurog, director of Martin and Lewis, Elvis Presley films
 - Bert Leston Taylor, librettist and columnist (born in Massachusetts)
 - Billy Taylor, basketball coach, Lehigh and Ball State
 - Eddie Taylor, guitarist in Blues Hall of Fame (born in Mississippi)
 - Edmund Dick Taylor, coal miner, politician, "Father of the Greenback" (born in Virginia)
 - George A. Taylor, World War II general, led Omaha Beach landing
 - Hawk Taylor, catcher for four MLB teams
 - Joan Taylor, actress, 20 Million Miles to Earth, War Paint, The Rifleman
 - Josh Taylor, actor, Days of Our Lives
 - June Taylor, choreographer, The Jackie Gleason Show
 - Koko Taylor, singer (born in Tennessee)
 - Lili Taylor, actress, Six Feet Under, I Shot Andy Warhol, Mystic Pizza, Ransom, The Conjuring
 - Robert Lewis Taylor, author, 1959 Pulitzer Prize
 - Samuel A. Taylor, screenwriter, Sabrina, Vertigo
 - Margaret Taylor-Burroughs, artist, museum founder, parks commissioner (born in Louisiana)
 - Edwin Way Teale, naturalist and Pulitzer Prize-winning writer
 - Gus Tebell, football coach, NC State, Virginia
 - Barbara Ann Teer, founder of National Black Theatre
 - Len Teeuws, lineman for NFL's Rams and Cardinals
 - Rick Telander, sportswriter for Sports Illustrated and Chicago Sun-Times
 - Lance Ten Broeck, pro golfer
 - Andy Tennant, actor, writer, film director, Hitch, Sweet Home Alabama, The Bounty Hunter
 - Bradie Tennell, figure skater, 2018 Winter Olympics medalist
 - Judy Tenuta, comedian
 - Studs Terkel, historian, journalist, Pulitzer Prize-winning author and actor, Eight Men Out
 - Ernie Terrell, heavyweight contender, Chicago boxing promoter (born in Mississippi)
 - Felisha Terrell, actress, Days of Our Lives
 - Jean Terrell, singer with The Supremes
 - Frank Teschemacher, jazz musician (born in Missouri)
 - Tim Tetrick, harness racing driver, won 2012 Hambletonian Stakes
 
Th–Tn
- John Thain, CEO of Merrill Lynch, New York Stock Exchange
 - Tom Thayer, offensive lineman and radio commentator for Chicago Bears
 - Mary Jane Theis, Chief Justice, Supreme Court of Illinois
 - Lynne Thigpen, actress, Where in the World Is Carmen Sandiego?, All My Children, The Paper, The District
 - Roy Thinnes, actor, The Invaders, Airport 1975, The Hindenburg, Falcon Crest
 - Napoleon B. Thistlewood, Cairo politician (born in Delaware)
 - Josh Thole, MLB catcher 2009-16
 - Bill Thomas, costume designer, 10 Oscar nominations
 - Deon Thomas, American-Israeli basketball player
 - Frank Thomas, Hall of Fame first baseman, DH for Chicago White Sox (born in Georgia)
 - Frazier Thomas, Chicago television personality (born in Indiana)
 - Isiah Thomas, Hall of Fame basketball player, coach, executive; NCAA champion Indiana, NBA champion Detroit Pistons
 - Jesse B. Thomas, one of state's first U.S. Senators (born in Virginia)
 - Lee Thomas, MLB player and executive
 - Pierre Thomas, running back for Super Bowl XLIV champion New Orleans Saints
 - Pinch Thomas, MLB catcher 1912–21
 - Robert R. Thomas, justice on Supreme Court of Illinois 2000-20, kicker for Notre Dame and Chicago Bears (born in New York)
 - Theodore Thomas, violinist, conductor and founder of the Chicago Symphony Orchestra (born in Germany)
 - Jim Thome, Hall of Fame first baseman, DH 1991–2012, five-time All-Star
 - Don Thompson, president of McDonald's 2012–15
 - Fountain L. Thompson, U.S. Senator of North Dakota
 - James R. Thompson, politician (Republican), U.S. Attorney and four-term Governor of Illinois
 - Jeri Kehn Thompson, political commentator, wife of Sen. Fred Thompson (born in Nebraska)
 - Junior Thompson, MLB pitcher 1939–47
 - Marshall Thompson, actor, Dial 1119, Crashout, My Six Convicts, To Hell and Back, It!, First Man into Space
 - Patricia Thompson, television and documentary producer
 - William Hale Thompson, politician (Republican), two-term Mayor of Chicago (born in Massachusetts)
 - James Thomson, developmental biologist
 - Brad Thor, thriller novelist
 - Skip Thoren, basketball center for Illinois 1962–65
 - Don Thorp, defensive lineman, 1983 Big Ten MVP
 - Noble Threewitt, horse racing trainer
 - Richard Threlkeld, television journalist (born in Iowa)
 - Paul Tibbets, pilot of Enola Gay, U.S. Air Force general
 - Eunice Tietjens, foreign correspondent
 - Pamela Tiffin, actress, One, Two, Three, The Pleasure Seekers, Harper (born in Oklahoma)
 - Charles Tillman, cornerback for Chicago Bears, Carolina Panthers
 - Dorothy Tillman, Chicago alderman 1985-2007 (born in Alabama)
 - Burr Tillstrom, puppeteer, creator of Kukla, Fran and Ollie
 - Tom Timmermann, MLB pitcher 1969–74
 - Joe Tinker, Hall of Fame shortstop for Chicago Cubs (born in Kansas)
 
To–Tq
- John Tobias, creator of Mortal Kombat video game
 - James Tobin, economist, 1981 Nobel Prize
 - Albert Tocco, organized crime figure
 - Beverly Todd, actress, Lean on Me, The Bucket List
 - Jonathan Toews, three-time Stanley Cup champion with Chicago Blackhawks (born in Canada)
 - JP Tokoto, player for Hapoel Tel Aviv of Israeli Basketball Premier League
 - Gregg Toland, Oscar-winning cinematographer, Citizen Kane, Wuthering Heights
 - Scott Tolzien, NFL quarterback 2011-17, assistant coach
 - David Tom, actor, The Young and the Restless, All My Children
 - Lauren Tom, actress and voice artist, King of the Hill, The Joy Luck Club, Futurama, W.I.T.C.H.
 - Nicholle Tom, actress, The Nanny, The Minor Accomplishments of Jackie Woodman, Her Only Child
 - Clyde Tombaugh, astronomer, discoverer of dwarf planet Pluto
 - Mike Tomczak, quarterback for four NFL teams
 - Darlene Tompkins, actress, Beyond the Time Barrier, Blue Hawaii
 - Mario Tonelli, football player, survivor of Bataan Death March
 - Judy Baar Topinka, politician (Republican), comptroller, state treasurer
 - Mel Tormé, singer, composer, actor, Grammy Lifetime Achievement Award, co-wrote "The Christmas Song"
 - Jorge Torres, NCAA cross-country champion
 - Johnny Torrio, organized crime figure (born in Italy)
 - Audrey Totter, actress, The Postman Always Rings Twice, The Set-Up, High Wall, Tension, Lady in the Lake
 - Cy Touff, trumpeter
 - Roger Touhy, organized crime figure
 - Tom Towles, actor
 - Andre Townsend, starter in two Super Bowls for Denver Broncos
 - Robert Townsend, actor and director, The Parent 'Hood, The Five Heartbeats, Hollywood Shuffle
 - Taylor Townsend, tennis player
 - Giorgio Tozzi, opera singer
 
Tr–Tz
- Al Trace, songwriter and bandleader
 - George Trafton, Hall of Fame center for Chicago Bears
 - Jane Trahey, advertising executive
 - Mary Ellen Trainor, actress, Roswell, Parker Lewis Can't Lose, the Lethal Weapon films
 - Rick Tramonto, restaurateur
 - June Travis, actress, Circus Girl, The Case of the Black Cat
 - Sam Travis, MLB infielder
 - Sam Treiman, theoretical physicist
 - Les Tremayne, radio personality (born in England)
 - Ken Trickey, college basketball coach (born in Missouri)
 - Roswell Tripp, football player for Yale
 - Dick Triptow, pro basketball player and coach
 - Lennie Tristano, jazz pianist
 - Walter Trohan, journalist
 - Harry Trotsek, Hall of Fame thoroughbred trainer
 - Bill Trotter, MLB pitcher 1937–44
 - Charlie Trotter, restaurateur
 - Bobbi Trout, aviatrix
 - Jim True-Frost, actor, The Wire
 - Walter E. Truemper, pilot, World War II Medal of Honor recipient
 - Frankie Trumbauer, jazz saxophonist
 - Lyman Trumbull, politician (Democrat, Republican), Illinois Supreme Court Justice, U.S. Senator, author of Thirteenth Amendment (born in Connecticut)
 - Bob Trumpy, tight end for Cincinnati Bengals, sportscaster
 - Morgan Tuck, four-time NCAA basketball champion for UConn
 - Alando Tucker, pro basketball player, 2007 Big Ten Player of the Year
 - Dennis Tufano, singer for The Buckinghams
 - Robin Tunney, actress, The Mentalist, Prison Break, The Craft, Hollywoodland, Vertical Limit
 - William Tuohy, Pulitzer-winning foreign correspondent
 - Barbara Turf, CEO of Crate & Barrel
 - Bob Turley, Cy Young-winning pitcher, primarily with New York Yankees
 - Bulldog Turner, Hall of Fame player for Chicago Bears (born in Texas)
 - Evan Turner, NBA guard 2010-20, second pick of 2010 NBA draft, 2010 Big Ten Player of the Year
 - Ike and Tina Turner, musical duo, began in East St. Louis
 - Jonathan Baldwin Turner, scholar, botanist, advocate of land grant universities (born in Massachusetts)
 - Keena Turner, linebacker for San Francisco 49ers, four-time Super Bowl champion
 - Michael Turner, NFL running back 2004–12
 - Stansfield Turner, admiral and CIA director
 - Scott Turow, author and lawyer, Presumed Innocent
 - Bill Tuttle, MLB outfielder 1952–63
 - Jeff Tweedy, musician with Wilco
 - Twista, rapper
 - R. Emmett Tyrrell Jr., founder, editor of The American Spectator
 
U
- Peter Ueberroth, president of U.S. Olympic Committee, commissioner of Major League Baseball
 - Ted Uhlaender, outfielder for Minnesota Twins and Cleveland Indians
 - Tyler Ulis, basketball player for Phoenix Suns (born in Michigan)
 - Chuck Ulrich, lineman for Illinois 1952 Rose Bowl championship team and NFL's Chicago Cardinals
 - Jim Umbricht, pitcher for Houston Colt .45s
 - Colton Underwood, football player, The Bachelor star (born in Indiana)
 - Lauren Underwood, U.S. Representative (born in Ohio)
 - Oliver A. Unger, movie producer, distributor and exhibitor
 - Kay Unger, fashion designer
 - Tim Unroe, MLB first baseman 1995–2000
 - Paul Unruh, 1950 All-America basketball player for Bradley
 - Al Unser, MLB catcher 1942–45
 - Del Unser, outfielder for six MLB teams
 - Phil Upchurch, jazz and R&B guitarist and bassist
 - Dawn Upshaw, Grammy-winning soprano
 - Calla Urbanski, pairs skater, two-time U.S. champion
 - Kraig Urbik, offensive lineman for Buffalo Bills
 - Urge Overkill, alt rock band from Chicago
 - Brian Urlacher, 13-year Chicago Bears linebacker, Pro Football Hall of Fame (born in Washington)
 - Frank Urson, silent-film director, Chicago
 - Garrick Utley, television journalist
 
V
- Richard B. Vail, World War I officer, U.S. Representative
 - Jerry Vainisi, general manager of Chicago Bears 1983–86
 - Jim Valek, football player, coach for Illinois
 - Darnell Valentine, NBA guard 1981–91
 - Elmer Valentine, founder of Whisky a Go Go and The Roxy Theatre
 - Vincent Valentine, defensive tackle for New England Patriots
 - Virginia Valli, silent movie actress
 - Egbert Van Alstyne, songwriter, "In the Shade of the Old Apple Tree"
 - John S. Van Bergen, architect
 - Al Van Camp, MLB first baseman, outfielder 1928–32
 - Danitra Vance, actress, Saturday Night Live cast member
 - Gene Vance, basketball player, athletic director for Illinois
 - Art Van Damme, accordionist (born in Michigan)
 - Christian Vande Velde, professional cyclist
 - James Oliver Van de Velde, second Bishop of Chicago (born in Belgium)
 - Shaun Vandiver, basketball player and coach
 - Carl Clinton Van Doren, author, 1939 Pulitzer Prize for biography
 - Mark Van Doren, professor, 1940 Pulitzer Prize for poetry
 - Wendelin Van Draanen, author of Sammy Keyes children's novels
 - Dick Van Dyke, actor, The Dick Van Dyke Show, Diagnosis: Murder, Bye Bye Birdie, Mary Poppins (born in Missouri)
 - Jerry Van Dyke, actor, comedian, Coach, The Courtship of Eddie's Father, My Mother the Car
 - Brian Van Holt, actor, Cougar Town, John from Cincinnati
 - Phillip Edward Van Lear, actor, Prison Break
 - Norm Van Lier, player and broadcaster for Chicago Bulls (born in Ohio)
 - Homer Van Meter, bank robber (born in Indiana)
 - Sander Vanocur, television news journalist
 - John M. Van Osdel, architect (born in Maryland)
 - Melvin Van Peebles, director, screenwriter, actor, composer
 - Jim Van Pelt, two-time Grey Cup champion CFL quarterback
 - Todd Van Poppel, MLB pitcher 1991–2004
 - Samuel Van Sant, Governor of Minnesota 1901–05
 - Virginia Van Upp, writer, producer, Cover Girl, Gilda
 - Virginia Van Wie, golfer, three-time U.S. Women's Amateur champion
 - Fred VanVleet, point guard, 2019 NBA champion with Toronto Raptors
 - Bruce Vaughan, golfer, winner of British Senior Open
 - Chico Vaughn, Southern Illinois and pro basketball player
 - Clarence Vaughn, NFL defensive back 1987–92
 - Govoner Vaughn, basketball player
 - Hippo Vaughn, pitcher for Cubs 1913–21 (born in Texas)
 - Vince Vaughn, actor, The Lost World: Jurassic Park, Wedding Crashers, Fred Claus, Psycho, The Break-Up
 - Eddie Vedder, lead vocalist for Pearl Jam
 - Bill Veeck, owner of Chicago White Sox, Cleveland Indians, St. Louis Browns, member of Hall of Fame
 - William Veeck Sr., sportswriter, president of Chicago Cubs
 - Nadine Velazquez, actress and model, My Name Is Earl, Flight
 - Rachel Veltri, actress and model
 - Robin Ventura, third baseman, manager for Chicago White Sox (born in California)
 - Rick Venturi, head football coach for Northwestern, defensive coordinator for four NFL teams
 - Mark Venturini, actor
 - Emil Verban, three-time All-Star infielder, played for 1944 World Series champion St. Louis Cardinals
 - Jim Verraros, singer, Season 1 of American Idol
 - Dick Versace, basketball coach, Bradley and Indiana Pacers (born in North Carolina)
 - Izabela Vidovic, actress, singer, The Fosters, About a Boy
 - Vince Vieluf, actor, Love, Inc., Rat Race
 - Marjorie Vincent, news broadcaster and 1991 Miss America
 - Jory Vinikour, harpsichordist and conductor
 - Steve Vinovich, actor
 - Craig Virgin, distance runner, three-time Olympian, won nine Big Ten track titles and NCAA cross country
 - John Vivyan, actor, Mr. Lucky
 - Alex Vlasic, NHL defenseman
 - Virgil W. Vogel, film and TV director
 - Rich Vogler, auto racer, five Indianapolis 500s
 - Deborah Voigt, opera singer
 - Mark Voigt, NASCAR driver
 - Bob Voigts, Northwestern football player and coach
 - Harry Volkman, 45-year Chicago television weather forecaster
 - Pete Vonachen, Minor League Baseball executive
 - Kevin Von Erich, professional wrestler
 - Rufus B. von KleinSmid, president, University of Southern California 1921-47, raised in Von KleinSmid Mansion
 - Edward Vrdolyak, politician, Chicago alderman 1971–87, convicted of fraud
 - George Vukovich, MLB outfielder 1980–85
 - Charles W. Vursell, sheriff of Marion County, Illinois, U.S. Representative 1943–59
 
W
Waa–Wam
- The Wachowskis, filmmakers, the Matrix trilogy
 - Charles H. Wacker, city planner, director of Chicago World's Fair
 - Dwyane Wade, Hall of Fame basketball player, three-time NBA champion with Miami Heat
 - Robert Wadlow, tallest man in U.S.
 - E. S. Wadsworth, merchant, railroad president (born in Connecticut)
 - Arthur L. Wagner, U.S. Army general
 - Audrey Wagner, pro baseball player
 - Gary Wagner, pitcher for Philadelphia Phillies 1965–69
 - Mike Wagner, defensive back for Pittsburgh Steelers, won four Super Bowls
 - Susan Wagner, financial executive, co-founder of BlackRock
 - Ken Wahl, actor, Wiseguy, The Wanderers, Fort Apache, the Bronx
 - Becky Wahlstrom, actress, Joan of Arcadia
 - Jerry Wainwright, basketball coach of DePaul 2005–10
 - Frank Wainright, tight end for four NFL teams
 - Lena Waithe, actress, writer, producer, The Chi, Master of None, Ready Player One
 - Dick Wakefield, MLB outfielder 1941–52
 - Tim Walberg, U.S. Representative of Michigan
 - Eliot Wald, TV and film comedy writer
 - Frank Waldman, screenwriter, The Party, Return of the Pink Panther
 - Randy Waldman, musician
 - Tom Waldman, screenwriter, High Time, Inspector Clouseau
 - Jim Walewander, MLB infielder 1987–93
 - Charles Rudolph Walgreen, founder of Walgreens
 - Albertina Walker, gospel singer
 - Antoine Walker, forward for five NBA teams
 - Bill Walker, MLB pitcher 1927–36
 - Chet Walker, forward for Bradley and Chicago Bulls (born in Michigan)
 - Clint Walker, actor, Cheyenne, The Dirty Dozen, Yellowstone Kelly
 - Dan Walker, Governor of Illinois 1973–77 (born in D.C.)
 - Darrell Walker, player for five NBA teams
 - Derrick Walker, tight end for three NFL teams
 - George W. Walker, auto designer, original Ford Thunderbird
 - June Walker, actress
 - Mysterious Walker, three-sport athlete, coach for University of Chicago (born in Nebraska)
 - Nella Walker, actress
 - Amy Wallace, author (born in California)
 - Chris Wallace, television journalist, Fox News Channel and CNN
 - David Foster Wallace, author (born in New York)
 - Henry Cantwell Wallace, U.S. Secretary of Agriculture 1921–24
 - Irving Wallace, author and screenwriter
 - Jean Wallace, actress, Jigsaw, The Big Combo
 - Martin R. M. Wallace, Union general in Civil War (born in Ohio)
 - Mike Wallace, Chicago radio-TV personality and CBS News journalist (born in Massachusetts)
 - Stan Wallace, defensive back for Chicago Bears 1954–59
 - W.H.L. Wallace, Union general in Civil War (born in Ohio)
 - Stephen Wallem, actor, Nurse Jackie
 - Hal Wallis, film producer, Casablanca, The Maltese Falcon, Gunfight at the O.K. Corral, Blue Hawaii, True Grit
 - Joe Wallis, MLB outfielder 1975–79
 - Laurie Walquist, quarterback for Chicago Bears 1924–31
 - Ed Walsh, pitcher and manager for Chicago White Sox, member of Hall of Fame (born in Pennsylvania)
 - Frank Walsh, pro golfer, 1932 PGA Championship runner-up
 - Matt Walsh, actor, Upright Citizens Brigade, Veep
 - Minnie Gow Walsworth, poet
 - Kevin Walter, NFL wide receiver 2003–13
 - Melora Walters, actress, Cold Mountain, Boogie Nights, Magnolia
 - Lloyd Walton, guard for Milwaukee Bucks 1976–80
 
Wan–Waz
- Sam Wanamaker, director and actor, The Spy Who Came in from the Cold, Superman IV, Guilty by Suspicion
 - Carl Wanderer, World War I hero, convicted murderer
 - Rudolf Wanderone, billiards' "Minnesota Fats" (born in New York)
 - Betty Wanless, baseball player
 - Aaron Montgomery Ward, retail businessman, creator of mail order catalog (born in New Jersey)
 - Arch Ward, journalist, creator of baseball All-Star Game and boxing's Golden Gloves
 - Wilbur Ware, jazz bassist
 - Marsha Warfield, actress, Night Court
 - Cy Warmoth, MLB player 1916–23
 - Henry C. Warmoth, Civil War officer, governor of Louisiana
 - Mark Warner, politician (Democrat), governor and U.S. senator of Virginia (born in Indiana)
 - Vespasian Warner, Civil War soldier, U.S. Representative
 - Elihu B. Washburne, U.S. Secretary of State under Ulysses S. Grant (born in Maine)
 - Hempstead Washburne, Mayor of Chicago 1891–93
 - Dinah Washington, singer, 1993 inductee in Rock and Roll Hall of Fame (born in Alabama)
 - Harold Washington, first African-American Mayor of Chicago
 - Mark Washington, NFL defensive back 1970–79
 - Stan Wasiak, managed 4,844 minor-league baseball games
 - Ted Wass, actor, Soap, Blossom, Oh, God! You Devil, Sheena, Curse of the Pink Panther
 - Muddy Waters, blues musician and songwriter, Grammy Lifetime Achievement Award (born in Mississippi)
 - Maurine Dallas Watkins, Chicago reporter who wrote stage play Chicago (born in Kentucky)
 - Jody Watley, singer, songwriter, record producer
 - Betty Jane Watson, singer and actress
 - Bobby Watson, actor
 - Deek Watson, original member of singing group The Ink Spots
 - James Watson, molecular biologist, geneticist, zoologist, co-discoverer of structure of DNA, winner of Nobel Prize
 - Minor Watson, actor, Boys Town, The Jackie Robinson Story
 - William Watson, actor, Lawman, Chato's Land
 - Chris Watt, guard, Notre Dame and NFL
 - May Theilgaard Watts, naturalist and writer
 - Bobby Wawak, auto racer
 - Ruby Wax, comedian, TV personality, Absolutely Fabulous, Girls on Top
 - Carol Wayne, actress, television personality, Heartbreakers
 - Nina Wayne, actress, Luv
 
Wb–Wg
- Frank Wead, aviator and Oscar-nominated screenwriter
 - Betty, Jean and Joanne Weaver, sisters in All-American Girls Professional Baseball League
 - Buck Weaver, third baseman for 1917 World Series champion White Sox and 1919 "Black Sox" (born in Pennsylvania)
 - Jason Weaver, actor, Smart Guy, Thea
 - Bill Webb, coach, executive with White Sox
 - Richard Webb, actor, Out of the Past, Distant Drums
 - Wellington Webb, mayor of Denver, Colorado 1991–2003
 - Jon Weber, jazz musician, NPR host
 - Pete Weber, hockey broadcaster
 - Mary Webster, actress
 - Stokely Webster, impressionist painter
 - Tracy Webster, basketball coach
 - Reinhold Weege, comedy writer, creator of TV series Night Court
 - Charles Weeghman, businessman, built Wrigley Field, owned Chicago Cubs (born in Indiana)
 - D. A. Weibring, professional golfer
 - Bill Weick, Greco-Roman wrestler and coach, member of the first U.S. Greco-Roman wrestling World Championships team in 1961
 - Tim Weigel, Chicago television broadcaster
 - Joseph "Yellow Kid" Weil, notorious con artist
 - Bob Weiland, pitcher for five MLB teams
 - Jane Weiller, golfer
 - Alvin M. Weinberg, nuclear physicist
 - Lawrence Weingarten, Oscar-winning film producer
 - Robbie Weinhardt, pitcher for Detroit Tigers
 - Phil Weintraub, MLB player, had 11-RBI game in 1944
 - Hymie Weiss, mobster, rival of Al Capone (born in Poland)
 - Lois Weisberg, created Chicago Blues Festival and Taste of Chicago
 - Burton Weisbrod, economist who pioneered theory of option value
 - Mark Weisbrot, economist, columnist
 - Mark Weiser, chief scientist at Xerox PARC
 - Bob Weiskopf, TV writer, I Love Lucy
 - Michael T. Weiss, actor, The Pretender, The Legend of Tarzan
 - Robbie Weiss, 1988 NCAA tennis champion
 - Johnny Weissmuller, athlete and actor, five-time Olympic swim gold medalist, star of Tarzan films (born in Hungary)
 - Raquel Welch, actress, One Million Years B.C., Fantastic Voyage, Bandolero!, The Last of Sheila, Myra Breckinridge
 - Jerry Weller, U.S. Representative 1995–2009
 - Orson Welles, actor and director, Citizen Kane, The Third Man, Touch of Evil (born in Wisconsin)
 - Judson Welliver, presidential speechwriter
 - Jon Wellner, actor, Henry Andrews on CSI: Crime Scene Investigation
 - Junior Wells, blues musician (born in Tennessee)
 - Randy Wells, pitcher for Chicago Cubs 2008–12
 - Marty Wendell, football player for Notre Dame
 - Joe Wendryhoski, NFL guard 1964–68
 - George Wendt, actor, Norm Peterson on television series Cheers
 - John Wentworth, politician (Democrat), U.S. Congressman, Mayor of Chicago and newspaper editor (born in New Hampshire)
 - Pete Wentz, bass player of Fall Out Boy
 - Dennis Werth, player for New York Yankees 1979–81
 - Jayson Werth, MLB outfielder 2002-17
 - Paul Wertico, drummer with Pat Metheny Group
 - Dallas West, billiards player
 - Kanye West, multiple Grammy Award-winning rap musician, songwriter, producer, fashion designer, actor; husband of reality TV star Kim Kardashian
 - Mary Allen West, journalist, editor, educator, social reformer
 - Matthew West, Christian musician
 - Roy Owen West, U.S. Secretary of the Interior 1928–29
 - Helen Westerman, baseball player
 - Thomas D. Westfall, mayor of El Paso, Texas 1978–82
 - Edward Weston, photographer
 - Haskell Wexler, Oscar-winning cinematographer, producer, director
 - Jerrold Wexler, financier
 
Wh
- Warren L. Wheaton, philanthropist, namesake of Wheaton, Illinois (born in Connecticut)
 - Cora Stuart Wheeler, poet, writer, journalist, lecturer
 - Loren E. Wheeler, mayor of Springfield, U.S. Representative
 - John Whistler, first commandant of Fort Dearborn (born in Ireland)
 - Betty White, Emmy-winning actress and comedian, The Golden Girls, The Mary Tyler Moore Show, The Proposal, Hot in Cleveland
 - Deacon White, baseball Hall of Famer (born in New York)
 - Frank White, eighth Governor of North Dakota, 1921–28 U.S. Secretary of Treasury
 - Isaac White, 19th Century militia officer (born in Virginia)
 - Jesse White, politician, Illinois Secretary of State
 - John H. White, Pulitzer Prize-winning photographer
 - Maurice White, musician, founder of Earth, Wind & Fire
 - Michole Briana White, actress
 - Nettie L. White, stenographer, suffragist
 - Stephanie White, basketball player and coach
 - Verdine White, musician, original member of Earth, Wind & Fire
 - Wendy White, opera singer
 - Willye White, track-and-field athlete, five-time Olympian
 - Jerome Whitehead, center-forward for Marquette, six NBA teams
 - John C. Whitehead, banker, civil servant, chairman of Lower Manhattan Development Corporation
 - Steven Whitehurst, author, poet, educator
 - Larry Whiteside, sportswriter, 2008 Spink Award winner
 - Samuel Whiteside, soldier and 19th Century member of U.S. General Assembly (born in North Carolina)
 - Richard A. Whiting, composer, "On the Good Ship Lollipop", "Hooray for Hollywood"
 
Wi
- Al Wickland, MLB outfielder 1913–19
 - Richard Widmark, Oscar-nominated actor, Judgment at Nuremberg, The Alamo, Kiss of Death, Night and the City, How the West Was Won, Murder on the Orient Express
 - Scott Wike, U.S. Representative, assistant treasury secretary to Grover Cleveland (born in Pennsylvania)
 - Michael Wilbon, sports columnist, co-host of ESPN's Pardon the Interruption
 - Wilco, rock band from Chicago
 - Linda Wild, tennis player
 - Lee and Lyn Wilde, actresses, Twice Blessed, Campus Honeymoon
 - Thornton Wilder, playwright, University of Chicago professor (born in Wisconsin)
 - Tim Wilkerson, drag racer
 - David B. Wilkins, Harvard law professor
 - Jeff Wilkins, center for Utah Jazz 1980–86
 - J. Ernest Wilkins Jr., nuclear scientist, University of Chicago student at 13
 - Steve Wilkos, television personality, The Jerry Springer Show, The Steve Wilkos Show
 - Bob Will, outfielder for Cubs 1957–63
 - George Will, conservative Pulitzer Prize-winning columnist, journalist, ABC news analyst, author
 - Alice Willard, journalist, editor
 - Frances E. Willard, suffragist, head of temperance union, Northwestern dean of women (born in New York)
 - Frank Willard, cartoonist, creator of Moon Mullins
 - Louise Collier Willcox, writer, editor, anthologist, translator
 - Lois Wille, Pulitzer Prize-winning journalist
 - Walt Willey, actor, All My Children
 - Aaron Williams, forward for 10 NBA teams
 - Billy Williams, 15-year outfielder for Cubs, member of Hall of Fame (born in Alabama)
 - Brandon Williams, NFL tight end
 - Cynda Williams, actress, Mo' Better Blues, One False Move
 - Dick Anthony Williams, actor, Homefront, The Mack, Dog Day Afternoon
 - Frank Williams, NBA and Illinois guard, 2001 Big Ten Player of the Year
 - Jason Williams, linebacker for five NFL teams
 - Jesse Williams, actor, Grey's Anatomy, Lee Daniels' The Butler
 - Joe Williams, jazz and blues singer, Count Basie Orchestra (born in Georgia)
 - Joe Williams, Olympic wrestler, three-time NCAA champion
 - Juice Williams, quarterback for Illinois
 - Kenny Williams, outfielder, executive for Chicago White Sox (born in California)
 - Kyle Williams, wide receiver for Denver Broncos
 - Mayo Williams, football player and music producer
 - Michelle Williams, R&B singer-songwriter, member of Destiny's Child, actress
 - Robin Williams, comedian and Oscar-winning actor, Good Will Hunting, Good Morning, Vietnam, Mrs. Doubtfire, Dead Poets Society, Mork & Mindy, Aladdin
 - Rip Williams, MLB player 1911–18
 - Ron Williams, CEO and chairman of Aetna Inc. 2006–11
 - Tex Williams, western swing musician
 - William E. Williams, three-term U.S. Representative
 - Richard S. Williamson, diplomat in George W. Bush administration
 - Sonny Boy Williamson, blues harmonica musician (born in Tennessee)
 - Dave Willock, actor, What Ever Happened to Baby Jane?
 - Dave Wills, baseball broadcaster for Tampa Bay Rays
 - Art Wilson, MLB catcher 1908–21
 - Ben Wilson, murdered high school basketball star
 - Bobby Wilson, NFL tackle 1991–94
 - Dan Wilson, MLB catcher 1992–2005, Seattle Mariners Hall of Fame
 - Dooley Wilson, singer, "Sam" in Casablanca (born in Texas)
 - Gahan Wilson, cartoonist
 - George Wilson, NFL player and coach
 - George Wilson, NBA center, played in two NCAA title games (born in Mississippi)
 - Gretchen Wilson, country music singer
 - Hack Wilson, Hall of Fame outfielder for Cubs, record-breaking 191-RBI season (born in Pennsylvania)
 - James H. Wilson, Civil War general
 - Kenneth L. Wilson, president of United States Olympic Committee 1953–65, Big Ten commissioner 1945–61
 - Martez Wilson, linebacker for three NFL teams
 - Parke Wilson, MLB catcher of 19th Century
 - Pete Wilson, politician, mayor of San Diego 1971–83, U.S. Senator 1983–91, Governor of California 1991–99
 - Richard G. Wilson, soldier, Medal of Honor winner
 - Thomas E. Wilson, founder of Wilson Sporting Goods (born in Canada)
 - Whip Wilson, actor in western films
 - William Warfield Wilson, four-term U.S. Representative
 - Frank Wilton, football coach, Miami University 1932–41
 - Hal Wiltse, MLB pitcher 1926–31
 - Verne Winchell, founder of Winchell's Donuts
 - Dorothy Wind, baseball player
 - William G. Windrich, Medal of Honor recipient from Korean War
 - Henry Haven Windsor, editor, founder of Popular Mechanics
 - Oprah Winfrey, iconic television host, actress, producer and media magnate (born in Mississippi)
 - Tommy Wingels, NHL wing 2010-18
 - Clare Winger, science-fiction writer
 - Dan Winkler, MLB relief pitcher
 - Roy Winsor, soap opera creator, Search for Tomorrow
 - Florence Hull Winterburn, writer, editor
 - Frank Winters, basketball coach
 - Nobby Wirkowski, CFL quarterback
 - Arthur Wirtz, owned Chicago Stadium, Chicago Blackhawks, Chicago Bulls, Detroit Red Wings
 - Bill Wirtz, 41-year president of Chicago Blackhawks
 - Rocky Wirtz, owner of Chicago Blackhawks
 - W. Willard Wirtz, U.S. Secretary of Labor under John F. Kennedy and Lyndon B. Johnson
 - Lindsay Wisdom-Hylton, WNBA player 2009–12
 - Al, Alvin and Whitey Wistert, members of College Football Hall of Fame
 - John Wittenborn, NFL kicker 1958–68
 - Tom Wittum, NFL punter 1973–77
 - Samuel Witwer, actor, Davis Bloome on Smallville
 
Wj–Wz
- Rick Wohlhuter, runner, 1976 Olympic bronze medalist in 800 meters
 - Gary K. Wolf, author of novel adapted into Who Framed Roger Rabbit
 - Hillary Wolf, actress, judo player, Home Alone, Home Alone 2
 - Raymond Wolf, football coach for North Carolina, Florida and Tulane
 - Ross Wolf, MLB pitcher 2008–13
 - Garrett Wolfe, running back for Northern Illinois and Chicago Bears
 - Ian Wolfe, actor, Bedlam, Julius Caesar
 - Roger Wolff, MLB pitcher 1941–46
 - Violet Bidwill Wolfner, owner of NFL's Chicago and St. Louis Cardinals 1947–62
 - Benson Wood, Civil War officer, U.S. Representative (born in Pennsylvania)
 - Corinne Wood, first female lieutenant governor of Illinois
 - Elizabeth Wood, director of Chicago Housing Authority 1937–54 (born in Japan)
 - James N. Wood, director of Art Institute of Chicago 1979–2004
 - John Wood, Governor of Illinois 1860–61, founder of Quincy, Illinois (born in New York)
 - Kerry Wood, 10-year pitcher for Cubs (born in Texas)
 - Mike Woodard, MLB infielder 1985–88
 - Cliff Woodbury, auto racer, third in 1926 Indy 500
 - Jim Woods, MLB infielder 1957–61
 - Ray Woods, first basketball All-American for Illinois 1915–17
 - Abe Woodson, NFL cornerback 1958–66 (born in Mississippi)
 - Bob Woodward, journalist for Washington Post, instrumental in Watergate scandal, co-author of All the President's Men
 - Neil Woodward, Naval officer, NASA astronaut
 - James Hutchinson Woodworth, U.S. Representative, Mayor of Chicago 1848–50 (born in New York)
 - John Maynard Woodworth, first U.S. Surgeon General (born in New York)
 - Collett E. Woolman, co-founder of Delta Air Lines
 - Ralph Works, MLB pitcher 1909–13
 - Stephen T. Worland, economist
 - Robert Wrenn, tennis player, one of Teddy Roosevelt's Rough Riders
 - Amy Wright, actress, The Accidental Tourist, The Scarlet Letter
 - Eric C. Wright, defensive back, four-time Super Bowl champion with San Francisco 49ers
 - Eugene Wright, bassist with Dave Brubeck Quartet
 - Frank Lloyd Wright, iconic architect, designer, writer and educator (born in Wisconsin)
 - Jeremiah Wright, retired pastor of Trinity United Church of Christ (born in Pennsylvania)
 - Joseph C. Wright, Oscar-winning art director
 - Julian Wright, pro basketball player
 - Margie Wright, softball Hall of Famer
 - Michael Wright, pro basketball player
 - Randy Wright, quarterback for Green Bay Packers 1984–88
 - Warren Wright Sr., owner of horse racing's Calumet Farm (born in Ohio)
 - P.K. Wrigley, chewing gum mogul, Chicago Cubs owner 1932–77
 - William Wrigley Jr., founder of Wrigley Company, majority owner of Cubs 1918–32 (born in Pennsylvania)
 - William Wrigley III, CEO of Wrigley Co., sold Cubs to Tribune Company
 - Jim Wulff, defensive back, 1956 Rose Bowl champion Michigan State
 - Vic Wunderle, archer, 2000 Olympic silver medalist
 - Alex Wurman, film and TV composer
 - Addie L. Wyatt, civil rights activist (born in Mississippi)
 - John Wyatt, pitcher for five MLB teams
 - Brooke Wyckoff, player for three WNBA teams
 - Victoria Wyndham, actress, Another World
 - Renaldo Wynn, player for four NFL teams
 - Marvell Wynne, MLB outfielder 1983–90
 - Johnny Wyrostek, MLB outfielder 1942–54
 
Y
- Rick Yager, cartoonist
 - Kevin Yagher, special effects technician
 - Luke Yaklich, basketball coach, Illinois-Chicago
 - Estelle Yancey, blues singer
 - Jimmy Yancey, jazz musician
 - Ron Yary, Hall of Fame offensive tackle, primarily with Minnesota Vikings, 1969 NFL champion
 - Richard Yates Sr., politician (Republican), U.S. Representative, U.S. Senator, Governor of Illinois 1861–65 (born in Kentucky)
 - Richard Yates Jr., politician (Republican), attorney, U.S. Representative, Governor of Illinois 1901–05
 - Sidney R. Yates, politician (Democrat), 49-year U.S. Representative
 - Leland B. Yeager, economist, expert on monetary policy and international trade
 - Molly Yeh, cookbook author, Food Network personality
 - Charles Yerkes, financier, mass-transit developer (born in Pennsylvania)
 - Mary Agnes Yerkes, painter
 - Philip Yordan, Oscar-winning screenwriter, Detective Story, Johnny Guitar, The Harder They Fall
 - Dick York, actor, Bewitched, Inherit the Wind (born in Indiana)
 - John J. York, actor, General Hospital, Werewolf
 - Bruce A. Young, actor, The Sentinel, Blink, The Color of Money
 - Bryant Young, Hall of Fame defensive lineman for Super Bowl XXIX champion San Francisco 49ers
 - Buddy Young, NFL running back and College Football Hall of Famer
 - Chic Young, creator of comic strip Blondie
 - Clara Kimball Young, actress
 - Donald Young, professional tennis player
 - Ella Flagg Young, superintendent of Chicago schools 1909–1915 (born in New York)
 - Ernie Young, outfielder for five MLB teams, minor-league manager, 2000 Olympic gold medalist
 - Frank A. Young, sportswriter for Chicago Defender
 - James Young, musician with Styx
 - John Young, jazz pianist
 - Larry Young, MLB umpire
 - Richard M. Young, judge, U.S. Senator 1837–43
 - Robert Young, actor, Father Knows Best, Marcus Welby, M.D., Crossfire, Northwest Passage, Western Union
 - Roger Young, writer, director, Lassiter, The Squeeze
 - Victor Young, Oscar-winning composer, arranger, violinist, conductor; wrote "When I Fall in Love", "Around the World"
 - Zora Young, blues singer (born in Mississippi)
 - Robin Yount, Hall of Fame player for Milwaukee Brewers
 - Linda Yu, television newscaster (born in China)
 - Jay Yuenger, musician with White Zombie
 - Rich Yunkus, basketball player
 - Timi Yuro, singer, "Hurt"
 - Kateryna Yushchenko, former First Lady of Ukraine
 
Z
- Florian ZaBach, musician and television personality
 - Courtney Zablocki, luge, fourth place at 2006 Turin Olympics
 - Jacob Zachar, actor, Greek
 - James Zagel, judge, novelist
 - Paula Zahn, journalist, TV personality, On the Case with Paula Zahn (born in Nebraska)
 - Timothy Zahn, science-fiction author
 - Naureen Zaim, model, actress, artist
 - Robin Zander, musician with Cheap Trick (born in Wisconsin)
 - Billy Zane, producer, director and actor, Titanic, The Phantom, Dead Calm, Only You, Sniper, Tombstone
 - Charles S. Zane, judge, associate of Abe Lincoln (born in New Jersey)
 - Lisa Zane, actress, L.A. Law, Biker Mice from Mars, Roar
 - John Zaremba, actor, I Led Three Lives, The Time Tunnel, Ben Casey
 - Agnes Zawadzki, figure skater, 2010 U.S. junior champion
 - Jed Zayner, professional soccer player
 - Tom Zbikowski, defensive back for Notre Dame and Baltimore Ravens
 - Larry Zbyszko, pro wrestler
 - Robert Z'Dar, actor, producer
 - Joe Zdeb, outfielder for Kansas City Royals 1977–79
 - Kara Zediker, actress
 - Stephen A. Zeff, accounting historian
 - John D. Zeglis, president of AT&T
 - Bill Zehme, magazine writer and author
 - Alfred Zeisler, film director
 - Fannie Bloomfield Zeisler, pianist (born in Austria)
 - Zeke Zekley, cartoonist
 - Pam Zekman, Pulitzer Prize-winning investigative journalist
 - Sarah Zelenka, world champion rower, fourth at 2012 Olympics
 - Sam Zell, real estate entrepreneur, Tribune Company chairman
 - Bob Zeman, pro football player and coach
 - Robert Zemeckis, film director, Forrest Gump, Cast Away, Who Framed Roger Rabbit, the Back to the Future films
 - Colleen Zenk, actress, As the World Turns
 - Warren Zevon, rock musician, singer-songwriter, "Werewolves of London"
 - Jeff Zgonina, defensive lineman for seven NFL teams
 - Howard Zieff, film and TV commercial director, The Main Event, Private Benjamin, My Girl
 - Florenz Ziegfeld, Broadway impresario, creator of Ziegfeld Follies
 - Alma Ziegler, pro baseball player
 - Brad Ziegler, MLB pitcher 2008-18 (born in Kansas)
 - Zach Ziemek, Olympic decathlete
 - Benny Zientara, MLB infielder 1941–48
 - Lester Ziffren, screenwriter
 - Mike Zimmer, head coach of Minnesota Vikings 2014-22
 - Frederick Hinde Zimmerman, banker and land owner
 - Jacob Zimmerman, editor, politician (born in Pennsylvania)
 - Mary Zimmerman, Tony Award-winning director (born in Nebraska)
 - Mary Beth Zimmerman, golfer, four-time Women's U.S. Amateur champion
 - Bob Zimny, lineman for 1947 NFL champion Chicago Cardinals
 - Bud Zipfel, first baseman for Washington Senators
 - Patricia Zipprodt, costume designer
 - Adrian Zmed, actor, TV personality, T. J. Hooker, Grease 2
 - Ben Zobrist, MLB second baseman 2006-19, two-time World Series champion
 - Robert Zoellick, president of World Bank 2007–12
 - Rick Zombo, hockey player for Detroit Red Wings, St. Louis Blues
 - Billy Zoom, guitarist for band X
 - Chris Zorich, lineman for Notre Dame and Chicago Bears
 - Louis Zorich, actor, musician, Mad About You, Brooklyn Bridge
 - Anthony E. Zuiker, creator of CSI
 - Jim Zulevic, actor, comedian, radio host, TV writer
 - Robert Zuppke, football coach for University of Illinois 1913–41, College Football Hall of Fame (born in Germany)
 - Jack Zuta, organized crime figure (born in Russia)
 - Edward Zwick, film director, Glory, The Last Samurai, Legends of the Fall, Love & Other Drugs, Defiance
 - Tony Zych, MLB pitcher 2015-17
 
0-9

Montana-of-300
Montana of 300, rapper
See also
References
- ↑ Willard 1893: 2, 3
 - ↑ Fox, Margalit (2018). "Margaret Abbott: The first American woman to win an Olympic championship". The New York Times. Retrieved December 31, 2019.
 - ↑ "Abbott-Sengstacke Family Papers". Chicago Public Library. Biographical Note. Retrieved December 31, 2019.
 - ↑ Abel, Jessica (June 25, 2006). "Last Comic Standing". Why I Write. The Examiner (Interview). Vol. CXLII, no. 11. Interviewed by Jeffrey M. Anderson. San Francisco, California. p. 23 – via Newspapers.com.
 - ↑ Staff (July 5, 1977). "Gertrude Abercrombie, 68, leading Chicago artist, dies". Metropolitan. Chicago Tribune (Obituary). Vol. 131, no. 186 (Final ed.). p. 9. Retrieved January 1, 2019.
 - ↑ Kennedy, Randy (September 15, 2004). "Max Abramovitz, 96, Dies, Architect of Avery Fisher Hall". The New York Times. Retrieved January 1, 2020.
 - ↑ "Ben L. Abruzzo (American Balloonist)". Encyclopaedia Britannica. 2019. Retrieved January 1, 2020.
 - ↑ Pascual, Psyche (May 28, 1992). "Tony Accardo; Reputed Chicago Mob Boss". Los Angeles Times. Retrieved January 1, 2020.
 - ↑ Leszczak 2015, p. 1.
 - ↑ Ron Acks. pro-football-reference.com _____ Smith, Isaac (April 25, 2019). "'He's an icon.' Friends and family remember former Carbondale football coach Frank Bleyer". The Southern Illinoisan. Carbondale, Illinois: Lee Enterprises. Retrieved January 1, 2020. _____ "Ron Acks College Stats". College Football. Sports Reference LLC. Retrieved January 1, 2020.
 - ↑ Sužiedélis 2011, pp. 38–9.
 - ↑ "Berle Adams dies at 92; co-founder of Mercury Records and an MCA executive". Obituaries. Los Angeles Times. August 29, 2009. Retrieved January 3, 2020.
 - ↑ "Franklin P. Adams, Columnist, Radio Panelist, Dies at 78". The Philadelphia Inquirer. Vol. 262, no. 84 (City ed.). Triangle Publications. Associated Press. March 24, 1960. p. 32 – via Newspapers.com.
 - ↑ Weiser-Alexander, Kathy (August 2017). "John Hicks Adams – California Sheriff and U.S. Deputy Marshal". Legends of America. Retrieved January 3, 2020.
 - ↑ "Katrina Adams". ITA Women's Hall of Fame. College of William and Mary. Retrieved January 3, 2020.
 - ↑
 - ↑ Katchmer 2009, p. 252.
 - ↑ Bateman, Selby and Hostetter 1913: 893
 - ↑ United States Congress. "Raymond S. McKeough (id: M000510)". Biographical Directory of the United States Congress.
 - ↑ United States Congress. "William B. McKinley (id: M000521)". Biographical Directory of the United States Congress.
 
Sources
- Bateman N, Selby P, Hostetter CL (1913). Bateman N, Selby P, Hostetter CL (eds.). Historical Encyclopedia of Illinois. Vol. 2 – via Google Books.
 - Katchmer, George A. (2009). A Biographical Dictionary of Silent Film Western Actors and Actresses. McFarland. ISBN 9781476609058. OCLC 909773565. 
...born in Morrison, Illinois, on January 23, 1872....
 - Leszczak, Bob (2015). Encyclopedia of Pop Music Aliases, 1950-2000. London: Rowman & Littlefield. ISBN 978-1-4422-4007-0 – via Google Books (preview).
 - Sužiedélis, Saulius (2011). Historical Dictionary of Lithuania (2nd ed.). Lanham, Maryland: Scarecrow Press (Rowman & Littlefield). ISBN 978-0-8108-4914-3 – via Google Books (preview).
 - Willard FE, Rice Livermore MA, eds. (1893). A Woman of the Century. Moulton – via Internet Archive (free eBook).
 
    This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.









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